What is a Cunningham panel?

The Cunningham Panel™ is a blood test which measures the levels of circulating autoantibodies associated with certain neurologic and psychiatric symptoms. Elevated levels indicate that symptoms may be due to an infection-driven autoimmune problem, rather than a neuropsychiatric disorder. Physician Ordering.
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Is the Cunningham panel worth it?

The Cunningham Panel demonstrated an overall accuracy of 86% to 90%, a sensitivity of 88% and a specificity of 83% to 92% when comparing clinical symptoms to test results.
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How much does Cunningham panel cost?

The Cunningham Panel™ Testing Costs

The cost of the Cunningham Panel™ of Tests is $925. This amount is the responsibility of the patient/responsible party.
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How long does the Cunningham panel take?

HOW DO I RECEIVE CUNNINGHAM PANEL™ RESULTS? Patient results are uploaded to our secure Prescriber Portal and you will be notified by e-mail when results are available. Please allow approximately 3-4 weeks for completion of testing for all five test in the panel.
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How do I order Cunningham panels?

Cunningham Panel™ Process
  1. Have your clinician prescribe the panel by placing an order on our secure prescriber portal, ordering on a script pad, or completing a paper requisition (available upon provider request from Moleculera Labs).
  2. Be sure to provide your clinician with a valid email address so we may contact you.
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Cunningham Panel: What the test measures



Who does the Cunningham panel?

The Cunningham Panel™ is unique and based on over two decades of research. It is offered exclusively through Moleculera Labs, Inc. and has been utilized by clinicians worldwide.
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Where can I buy Cunningham panels?

Locating a lab to draw blood for The Cunningham Panel™
  • Your family doctor's office or clinic.
  • A small local clinical laboratory (Perform an internet search for “clinical laboratories” in your city or county)
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What are the symptoms of pans?

What Are the Symptoms of PANDAS and PANS?
  • tics or jerky movements.
  • anxiety, depression, or mood swings.
  • acting aggressive or "hyper"
  • using baby talk, acting clingy, or having new bedtime fears.
  • sudden trouble with handwriting or other fine motor skills.
  • new trouble with memory, reading, or math.
  • new bedwetting, not sleeping.
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What are the symptoms of PANDAS?

PANDAS Symptoms Checklist
  • Sudden onset of OCD-like symptoms.
  • Irritability or aggression.
  • Depression or extreme moodiness.
  • Poor motor coordination.
  • Tics or unusual movements.
  • Sensitivity to light, sound or touch.
  • Visual hallucinations.
  • Sleep disturbances or fatigue.
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Can PANDAS be treated?

Treatment with Antibiotics

The best treatment for acute episodes of PANDAS is to treat the strep infection causing the symptoms, if it is still present, with antibiotics. A throat culture should be done to document the presence of strep bacteria in the throat.
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Is pans an autoimmune disease?

PANS and PANDAS are infection-induced autoimmune conditions that disrupt a patient's normal neurologic functioning, resulting in a sudden onset of Obsessive Compulsive Disorder (OCD) and/or motor tics.
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Does PANDAS syndrome go away?

Although it may take time, most children who have PANDAS recover completely with treatment. Symptoms tend to slowly get better over several months once the strep infection clears, but there may be ups and downs. PANDAS is likely to come back if your child gets strep again.
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What is the cause of PANDAS disease?

PANDAS is caused by the body's immune reaction to strep, not the infection itself (Swedo & Grant, 2005). When an infection happens, the body's immune system makes a variety of proteins to help fight the bacteria. Some of these proteins are called antibodies and can be clinically measured.
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Does pans ever go away?

PANS/PANDAS is an “episodic illness”, meaning symptoms can go away for a while after an infection is treated, but they can come back again, in what is called a flare-up or relapse of the disorder.
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Can PANDAS cause autism?

As a mother of two children that have been diagnosed with PANDAS, the symptoms are real, the treatment is real and no, they don't have autism. Severe motor tics, OCD, behavioural and sensory issues will appear almost overnight and disappear with treatment of penicillin and anti inflammatories.
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How is PANDAS disease diagnosed?

While there is no definitive test for PANDAS at this time, your provider can use several tests, including strep cultures, allergy tests, immunological tests, brain scans and the Cunningham panel (a test that determines the likelihood that the patient's disorder is autoimmune in nature) among others to give you a PANDAS ...
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Can adults develop PANDAS?

Doctors consider PANDAS to be a childhood disorder that appears between the ages of 3 and 12 years. While it is possible that an adult or teenager might develop PANDAS, research has not explored this issue in depth.
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Can PANDAS be mild?

PANS/PANDAS TREATMENT GUIDELINES: MILD CASE

Mild: Symptoms are significant and cause disruptions at home and/or school. They occupy a few hours a day. The PANDAS Physicians Network (PPN) flowcharts for diagnosis and treatment will help clinicians evaluate their patients and determine the best course of treatment.
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Can PANDAS be cured with antibiotics?

If symptoms of PANS or PANDAS persist despite treatment, or if no infection can be found, then the patient should be referred to our service for comprehensive evaluation. Antibiotics can dramatically improve many patients' neuropsychiatric symptoms.
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How do you get PANS disease?

The cause of PANS is unknown in most cases but is thought to be triggered by infections, metabolic disturbances, and other inflammatory reactions.
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Can PANS cause bipolar?

It is hypothesized that part of the significant rise in the number of youngsters being given the diagnosis of Pediatric Bipolar Disorder, may be due to the lack of recognition of PANS and / or PANDAS.
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Are PANS genetic?

We believe children who develop PANS or PANDAS have a genetic predisposition for these syndromes, which are triggered by an environmental stressor, often an infection. With PANS, that trigger is unknown. PANDAS is thought to be triggered by a Streptococcal infection.
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What are the symptoms of PANDAS in adults?

What are the symptoms?
  • obsessive, compulsive, and repetitive behaviors.
  • separation anxiety, fear, and panic attacks.
  • incessant screaming, irritability, and frequent mood changes.
  • emotional and developmental regression.
  • visual or auditory hallucinations.
  • depression and suicidal thoughts.
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What kind of doctor treats pandas syndrome?

Doctors who treat PANDAS syndrome come from a variety of backgrounds. Pediatrics, neurology, hematology/oncology, psychology, psychiatry, integrative medicine, immunology and rheumatology are just a few of the specialties of PANDAS doctors.
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What antibiotics treat PANDAS?

Azithromycin and penicillin have been utilized in the treatment of PANDAS with observations of improvement in neuropsychiatric symptoms.
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