What if chemo doesn't work for leukemia?

If chemotherapy does not work, a possible alternative treatment option is a bone marrow or stem cell transplant
stem cell transplant
Stem cell transplants are used to treat conditions in which the bone marrow is damaged and is no longer able to produce healthy blood cells. Transplants can also be carried out to replace blood cells that are damaged or destroyed as a result of intensive cancer treatment.
https://www.nhs.uk › conditions › stem-cell-transplant
. Before transplantation can take place, the person receiving the transplant will need intensive high-dose chemotherapy, and possibly radiotherapy, to destroy the cells in their bone marrow.
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Why can leukemia not be cured?

As with other types of cancer, there's currently no cure for leukemia. People with leukemia sometimes experience remission, a state after diagnosis and treatment in which the cancer is no longer detected in the body. However, the cancer may recur due to cells that remain in your body.
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How many times can you have chemotherapy for leukemia?

Treatment for recurrent ALL depends on the length of the remission and is usually given in cycles for 2 to 3 years. If a recurrence occurs after a long remission, the leukemia may respond again to the original treatment. If the remission was short, then other drugs are used.
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How long is leukemia in remission?

Remission Timeline

It's hard to say how long your remission will last. It depends on your treatment, age, and overall health. Remissions may last as much as 3-5 years after your first retreatment. Because future retreatments usually don't work as well as the first one, your next remissions may be shorter.
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How successful is chemotherapy for leukemia?

According to the American Cancer Society (ACS), around 90 percent of people with an AML type known as acute promyelocytic leukemia (APL) will go into remission after “induction” (first round) of chemo. For most other types of AML, the remission rate is around 67 percent.
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Cancer Patient Refuses Chemotherapy | Good Morning Britain



What are the last stages of leukemia?

End stage leukemia
  • Slow breathing with long pauses; noisy breathing with congestion.
  • Cool skin that may turn a bluish, dusky color, especially in the hands and feet.
  • Dryness of mouth and lips.
  • Decreased amount of urine.
  • Loss of bladder and bowel control.
  • Restlessness or repetitive, involuntary movements.
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Can leukemia go into remission?

Most often, acute myeloid leukemia (AML) will go into remission after the initial treatment. But sometimes it doesn't go away completely, or it comes back (relapses) after a period of remission. If this happens, other treatments can be tried, as long as a person is healthy enough for them.
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Is leukemia always fatal?

Today, the average five-year survival rate for all types of leukemia is 65.8%. That means about 69 of every 100 people with leukemia are likely to live at least five years after diagnosis. Many people will live much longer than five years. The survival rates are lowest for acute myeloid leukemia (AML).
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What are the symptoms of leukemia relapse?

The symptoms of relapsed ALL are the same as those for newly diagnosed ALL, including:
  • Anemia.
  • Bone and joint pain.
  • Bruising or petechiae (small red spots on the skin)
  • Fever.
  • Recurrent infections.
  • Abdominal pain.
  • Swollen lymph nodes.
  • Dyspnea or difficulty breathing.
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How successful is leukemia treatment?

The cure rates and survival outcomes for patients with ALL have improved over the past few decades. Today, nearly 90 percent of adults diagnosed with ALL achieve a complete remission, which means that leukemia cells can no longer be seen in the bone marrow with a microscope.
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Which type of leukemia is most curable?

While it is similar in many ways to the other subtypes, APL is distinctive and has a specific treatment regime. Treatment outcomes for APL are very good, and it is considered the most curable type of leukemia, with cure rates as high as 90%.
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What are the 5 stages of leukemia?

What are the stages of CLL?
  • Stage 0. The blood has too many white blood cells called lymphocytes. This is called lymphocytosis. ...
  • Stage I. The blood has too many lymphocytes. ...
  • Stage II. The blood has too many lymphocytes. ...
  • Stage III. The blood has too many lymphocytes. ...
  • Stage IV. The blood has too many lymphocytes.
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Which of the following complications are three main consequences of leukemia?

Answer: B.

The three main consequences of leukemia are anemia, caused by decreased erythrocyte production; infection secondary to neutropenia; and bleeding tendencies, from decreased platelet production.
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Can you live 20 years with leukemia?

People in stages 0 to II may live for 5 to 20 years without treatment. CLL has a very high incidence rate in people older than 60 years. CLL affects men more than women. If the disease has affected the B cells, the person's life expectancy can range from 10 to 20 years.
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What percent of leukemia patients survive?

Latest figures show that the 5-year survival rate for all subtypes of leukemia is 61.4 percent . A 5-year survival rate looks at how many people are still alive 5 years after their diagnosis. Leukemia is most common in people aged over 55, with the median age of diagnosis being 66.
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Can you live a long life after leukemia?

Chronic lymphocytic leukemia (CLL) can rarely be cured. Still, most people live with the disease for many years. Some people with CLL can live for years without treatment, but over time, most will need to be treated. Most people with CLL are treated on and off for years.
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How many times can you relapse with leukemia?

Between 10% and 20% of patients, who have achieved complete remission after initial treatment for ALL, will have a relapse. In children, the relapse rate is near to 10%, while in adults relapse rate is closer to 50%.
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Can you survive leukemia relapse?

Results. The median overall survival after relapse was 4.5 months (95% CI, 4–5 months) with a 5-year overall survival of 10% (95% CI, 8%–12%); 45% of patients receiving intensive second-line treatment achieved a second complete remission and 22% (95% CI, 14%–30%) of them remained disease free at 5 years.
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When does leukemia usually relapse?

This can happen anywhere between several months to several years after initial treatment, with most relapses occurring within 2 to 3 years of initial treatment.
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How do you know when a leukemia patient is dying?

Worsening weakness and exhaustion. A need to sleep much of the time, often spending most of the day in bed or resting. Weight loss and muscle thinning or loss. Minimal or no appetite and difficulty eating or swallowing fluids.
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Is death from leukemia painful?

One 2015 study found that pain is the symptom people most commonly report during end-stage AML. People with AML may experience bone pain in the arms, hips, ribs, and breastbone as cancer cells overcrowd the bone marrow. People report experiencing either a sharp pain or constant dull ache.
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What happens when leukemia spreads to the spine?

Leukemia cells can spread to the central nervous system and build up in the fluid surrounding the spine and the brain. This can cause symptoms like headaches, seizures, balance problems, and abnormal vision.
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Is there hope for leukemia patients?

When you hear the word leukemia, your mind automatically goes to the past, when there was little hope of survival. Today, things have changed for many leukemia patients. Leukemia, a type of blood cancer defined by too many white blood cells, is different for each patient.
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Does leukemia always relapse?

Most people who are treated go into remission, but it doesn't always last. A relapse means that your leukemia has come back. Keep in mind that if your cancer returns, you still have treatment options.
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Can leukemia come back during treatment?

You may be relieved to finish treatment, but find it hard not to worry about the leukemia coming back. (When leukemia comes back after treatment, it is called a relapse or recurrence.) This is a very common concern in people who have had leukemia. For other people, the leukemia may not go away completely.
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