What happens when a mole biopsy comes back abnormal?

If the biopsy shows a mildly or moderately atypical mole, and it has been removed fully, no further treatment is needed. Moles that are severely atypical under the microscope may need a slightly wider surgery to ensure that they do not grow back.
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What does an abnormal mole biopsy mean?

An abnormal mole could be a melanoma symptom, or it could be benign, meaning it's not cancerous. To determine what type of cells make up the mole, the dermatologist will remove the mole for a biopsy. “A skin biopsy is usually a straight-forward procedure,” says Saira George, M.D., MD Anderson dermatologist.
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Does an abnormal skin biopsy mean cancer?

A normal biopsy result means no cancer or skin disease was found. An abnormal biopsy result may diagnose a specific skin condition. But sometimes abnormal results aren't clear, and you may need more tests to find out exactly what condition you have. Your provider can explain what your results mean.
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What percentage of abnormal moles are cancer?

Though moles can turn into cancer, or melanoma, it is rare. According to the National Library of Medicine, only 20 to 30 percent of melanomas arise from preexisting moles. Most precancerous skin lesions occur in areas that would otherwise be considered normal, healthy skin.
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Does an abnormal mole mean cancer?

An atypical mole is not a skin cancer but having these moles is a risk factor for developing melanoma. Although rare, melanoma can arise in association with atypical moles. That is why it is important to be aware of these moles, get them checked by your dermatologist, and watch out for changing moles.
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Mole Biopsy Finds Melanoma



Can a mole be abnormal but not cancer?

Also called dysplastic moles, atypical moles may be genetic or caused by damage from sun exposure. About 1 in 10 people develop atypical moles during their lifetime. These moles are not cancerous, and need not be removed if they are not changing.
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How often are abnormal moles cancerous?

It is suggested that only about 20-30% of melanomas arise from within pre-existing moles. This means that the vast majority of melanomas—70-80%—arise as new, abnormal spots on normal skin, and it also underscores why removing atypical moles would not be enough to prevent cancer.
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Where are most cancerous moles found?

They most often develop in areas that have had exposure to the sun, such as your back, legs, arms and face. Melanomas can also occur in areas that don't receive much sun exposure, such as the soles of your feet, palms of your hands and fingernail beds. These hidden melanomas are more common in people with darker skin.
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What happens if a mole biopsy is positive?

Generally, after a patient receives positive melanoma results, his or her doctors will need to proceed with staging the malignancy— which essentially means determining the extent of the cancer—and developing a treatment plan based on how far the cancer has progressed.
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What happens if you have a cancerous mole removed?

The removed tissue will be checked to make sure that there are no remaining melanoma cells along the edges. Your dermatologist may call the edges “margins.” If there are no cancer cells at the edges, that usually means the melanoma on the skin has been completely removed.
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Can you tell what stage cancer is from biopsy?

Doctors use diagnostic tests like biopsies and imaging exams to determine a cancer's grade and its stage. While grading and staging help doctors and patients understand how serious a cancer is and form a treatment plan, they measure two different aspects of the disease.
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What can cause an abnormal biopsy?

Abnormal biopsy results may be due to:
  • Cervical cancer.
  • Cervical intraepithelial neoplasia (precancerous tissue changes that are also called cervical dysplasia)
  • Cervical warts (infection with human papilloma virus , or HPV)
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Can you tell the grade of cancer from a biopsy?

A biopsy also helps your care provider determine how aggressive your cancer is — the cancer's grade. The grade is sometimes expressed as a number on a scale of 1 to 4 and is determined by how cancer cells look under the microscope.
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What is considered an abnormal mole?

Atypical moles are often larger than common moles and have regular or ragged or blurred borders that are not easy to see. Colors of atypical moles may be the same as the rest of the skin, or lighter, darker, or uneven. Parts or all of the mole may be raised above the skin surface.
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What does a suspicious cancerous mole look like?

Multiple colors are a warning sign. While benign moles are usually a single shade of brown, a melanoma may have different shades of brown, tan or black. As it grows, the colors red, white or blue may also appear.
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What are the signs that a mole might be cancerous?

Normal moles are generally round or oval, with a smooth edge, and usually no bigger than 6mm in diameter. But size is not a sure sign of melanoma.
...
Signs to look out for include a mole that's:
  • getting bigger.
  • changing shape.
  • changing colour.
  • bleeding or becoming crusty.
  • itchy or sore.
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What is the next step after a positive biopsy?

If you have a biopsy resulting in a cancer diagnosis, the pathology report will help you and your doctor talk about the next steps. You will likely be referred to a breast cancer specialist, and you may need more scans, lab tests, or surgery.
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What do doctors do if they think a mole is cancerous?

Diagnosing melanoma

Speak to your GP if you notice any change to your moles. Your GP will refer you to a specialist clinic or hospital if they think you have melanoma. In most cases, a suspicious mole will be surgically removed and studied to see if it is cancerous. This is known as a biopsy.
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Can a dermatologist tell if a mole is cancerous just by looking at it?

A visual check of your skin only finds moles that may be cancer. It can't tell you for sure that you have it. The only way to diagnose the condition is with a test called a biopsy. If your doctor thinks a mole is a problem, they will give you a shot of numbing medicine, then scrape off as much of the mole as possible.
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What are the 5 warning signs of malignant melanoma?

The "ABCDE" rule is helpful in remembering the warning signs of melanoma:
  • Asymmetry. The shape of one-half of the mole does not match the other.
  • Border. The edges are ragged, notched, uneven, or blurred.
  • Color. Shades of black, brown, and tan may be present. ...
  • Diameter. ...
  • Evolving.
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How quickly should melanoma be removed?

Hypothesis-based, informal guidelines recommend treatment within 4–6 weeks. In this study, median surgical intervals varied significantly between clinics and departments, but nearly all were within a 6-week frame. Key words: melanoma, surgical interval, treatment time, melanoma survival, time factors.
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What does a cancerous mole look like in early stages?

Border that is irregular: The edges are often ragged, notched, or blurred in outline. The pigment may spread into the surrounding skin. Color that is uneven: Shades of black, brown, and tan may be present. Areas of white, gray, red, pink, or blue may also be seen.
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How long can you live with a cancerous mole?

Survival for all stages of melanoma

almost all people (almost 100%) will survive their melanoma for 1 year or more after they are diagnosed.
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What stage is precancerous melanoma?

Stage 0 is known as “melanoma in situ” and is considered to be precancerous. Stage I and II melanomas are considered to be local (or localized) disease. Stage III melanoma is referred to as regional disease, and Stage IV is known as distant metastatic or advanced disease.
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How long does it take for a precancerous mole to become cancerous?

It could take 10 years or more to happen. Having the potential to develop into cancer. A precancerous condition can (or is likely to) become cancerous (malignant). Also called premalignant.
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