What happens if you take diclofenac for too long?

Is it safe to take long term? Diclofenac tablets and capsules can cause an ulcer in your stomach or gut if you take them for a long time or in big doses. There's also a small risk of heart failure or kidney failure if you take very big doses (150mg a day) for a long time.
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Can diclofenac be used long term?

Keep using this medicine for the full time of treatment. However, do not use this medicine more often or for a longer time than your doctor ordered. This medicine is not for long-term use.
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What are the short term risks associated while taking diclofenac?

Some possible warning signs of serious side effects that can occur during treatment with this medicine may include black, tarry stools, decreased urination, severe stomach pain, skin rash, swelling of the face, fingers, feet, or lower legs, unusual bleeding or bruising, unusual weight gain, vomiting of blood or ...
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Can I take diclofenac 50 mg daily?

Usual Adult Dose for Pain

Diclofenac potassium immediate-release tablets: 50 mg orally 3 times a day; an initial dose of 100 mg orally followed by 50 mg oral doses may provide better relief in some patients.
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Can you get withdrawal symptoms from diclofenac?

Patients treated with diclofenac had a similar risk of withdrawals due to an adverse event to ibuprofen and naproxen and higher risk compared to celecoxib and etoricoxib. The risk of withdrawal due to lack of efficacy for diclofenac was lower than ibuprofen and celecoxib and similar to etoricoxib and naproxen.
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How and When to use Diclofenac? (Voltaren, Cataflam, Cambia, Zorvolex)



Is diclofenac harmful to kidneys?

Diclofenac and other non-steroidal anti-inflammatory drugs (NSAID's) cause the kidney to lose the capacity to make these protective hormones and over time, can result in progressive kidney damage. This damage may take years in some people but in others can occur after a single dose.
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Why do doctors not prescribe diclofenac?

The Feb. 12, 2013 study in PLoS Medicine (2013;10:e1001388) indicates that diclofenac use can increase the risk of heart attack or stroke in patients with pre-existing conditions such as diabetes, high cholesterol or other high risk factors for cardiovascular problems.
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What are the most common side effects of diclofenac?

More common
  • Acid or sour stomach.
  • blood in the urine or stools.
  • bloody or black, tarry stools.
  • burning while urinating.
  • cloudy urine.
  • decrease in urine output or decrease in urine-concentrating ability.
  • feeling of indigestion.
  • headache.
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What should you not take with diclofenac?

Common medications that may interact with diclofenac include:
  • ACE inhibitors or ARBs, such as captopril, enalapril, or losartan.
  • Antibiotics, such as ciprofloxacin or vancomycin.
  • Anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin.
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Is diclofenac a strong painkiller?

Diclofenac is considered more potent than ibuprofen and needs to be taken two or three times per day. Ibuprofen often needs to be taken in higher doses to treat pain from arthritis.
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How long can I take diclofenac?

For arthritis, you may need to use the gel for up to 7 days on the painful joint to feel the full effect. Depending on why you're taking diclofenac, you may only need to take it for a short time. For example, if you have a sore back or toothache, you may only need to take diclofenac for 1 or 2 days.
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Can diclofenac cause depression?

Irritability, depression or anxiety. Serious blistering or peeling skin reactions (eg Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis).
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Can I have a glass of wine while taking diclofenac?

Do not drink alcohol while taking diclofenac. Alcohol can increase your risk of stomach bleeding caused by diclofenac. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
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Can diclofenac cause blood clots?

Diclofenac in clinically administered doses does not interfere with the function of platelets and does not cause increased bleeding.
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What kind of pain does diclofenac relieve?

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain.
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Can I drink coffee with diclofenac?

“In conclusion, caffeine produces antinociceptive synergism when administered in combination with diclofenac , and this synergism is partially mediated by opioid mechanisms at the central level.”
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Can I take diclofenac at bedtime?

Adults—25 milligrams (mg) 4 times a day, with an extra 25 mg dose at bedtime if necessary.
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Does diclofenac cause fluid retention?

Fluid retention: Diclofenac may cause fluid retention and swelling, possibly worsening high blood pressure, congestive heart failure, or decreased heart function.
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Does diclofenac raise blood pressure?

Diclofenac does not increase the risk of hypertension, but does increase the risk of stroke. Naproxen (Naprosyn) does not increase the risk of hypertension or stroke.
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Is diclofenac good for nerve pain?

Diclofenac sodium (DS), one of these NSAIDs, has a high specificity for arachidonic acid-degrading cyclooxygenase (COX)-2 enzymes. This drug can be used to relieve neuropathic pain.
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How often can you take diclofenac?

The usual dose is 25–50 mg up to 3 times a day (every 8 hours) OR 75 mg up to twice a day (every 12 hours). Always take your diclofenac exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much to take, how often to take it and any special instructions.
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Is diclofenac stronger than tramadol?

We found that both diclofenac and tramadol are equally effective in decreasing the pain associated with AP. There is also no significant difference in the incidence of side effects between both the groups. Hence both diclofenac and tramadol can be used safely and effectively for pain control in AP.
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Can diclofenac cause liver damage?

3) Diclofenac (Voltaren, Cambia)

Any NSAID (non-steroidal anti-inflammatory drug) can cause liver injury, although it's very rare. This class of medications includes popular drugs like ibuprofen and naproxen. But when it comes to liver injury, diclofenac is the NSAID with the highest risk.
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What are the side effects of diclofenac 75 mg?

Upset stomach, nausea, heartburn, diarrhea, constipation, gas, headache, drowsiness, and dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
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Can kidneys recover from NSAID damage?

Renal function will recover in most patients after withdrawal of NSAID therapy. Steroids may aid recovery in patients with interstitial nephritis who do not improve after stopping NSAID therapy.
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