What happens if a mole biopsy comes back abnormal?

If the biopsy shows a mildly or moderately atypical mole, and it has been removed fully, no further treatment is needed. Moles that are severely atypical under the microscope may need a slightly wider surgery to ensure that they do not grow back.
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What does an abnormal mole biopsy mean?

An abnormal mole could be a melanoma symptom, or it could be benign, meaning it's not cancerous. To determine what type of cells make up the mole, the dermatologist will remove the mole for a biopsy. “A skin biopsy is usually a straight-forward procedure,” says Saira George, M.D., MD Anderson dermatologist.
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Does an abnormal mole mean cancer?

An atypical mole is not a skin cancer but having these moles is a risk factor for developing melanoma. Although rare, melanoma can arise in association with atypical moles. That is why it is important to be aware of these moles, get them checked by your dermatologist, and watch out for changing moles.
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How likely are abnormal moles cancerous?

Only rarely does a common mole turn into melanoma, the most serious type of skin cancer. Although common moles are not cancerous, people who have many small moles or several large ones have an increased risk of developing melanoma (1).
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What happens if a mole biopsy comes back cancerous?

Generally, after a patient receives positive melanoma results, his or her doctors will need to proceed with staging the malignancy— which essentially means determining the extent of the cancer—and developing a treatment plan based on how far the cancer has progressed.
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Mole Biopsy Finds Melanoma



What do doctors do if they think a mole is cancerous?

Diagnosing melanoma

Speak to your GP if you notice any change to your moles. Your GP will refer you to a specialist clinic or hospital if they think you have melanoma. In most cases, a suspicious mole will be surgically removed and studied to see if it is cancerous. This is known as a biopsy.
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What are the symptoms of Stage 1 melanoma?

The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanomas can develop anywhere on your body.
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Can abnormal moles be benign?

Atypical moles are benign pigmented lesions. Although they are benign, they exhibit some of the clinical and histologic features of malignant melanoma. They are more common in fair-skinned individuals and in those with high sun exposure.
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How long can you live with a cancerous mole?

Survival for all stages of melanoma

almost all people (almost 100%) will survive their melanoma for 1 year or more after they are diagnosed.
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What makes a mole abnormal?

Atypical moles are often larger than common moles and have regular or ragged or blurred borders that are not easy to see. Colors of atypical moles may be the same as the rest of the skin, or lighter, darker, or uneven. Parts or all of the mole may be raised above the skin surface.
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What does a suspicious cancerous mole look like?

A for Asymmetry: One half of a mole or birthmark does not match the other. B for Border: Edges are irregular, ragged, notched or blurred. C for Color: The color is not uniform and may include shades of brown or black, and even patches of pink, red, white or blue.
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What are the signs that a mole might be cancerous?

Normal moles are generally round or oval, with a smooth edge, and usually no bigger than 6mm in diameter. But size is not a sure sign of melanoma.
...
Signs to look out for include a mole that's:
  • getting bigger.
  • changing shape.
  • changing colour.
  • bleeding or becoming crusty.
  • itchy or sore.
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How long does it take for a precancerous mole to become cancerous?

It could take 10 years or more to happen. Having the potential to develop into cancer. A precancerous condition can (or is likely to) become cancerous (malignant). Also called premalignant.
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What happens if your skin biopsy is abnormal?

An abnormal biopsy result may diagnose a specific skin condition. But sometimes abnormal results aren't clear, and you may need more tests to find out exactly what condition you have. Your provider can explain what your results mean.
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How often are mole biopsies cancerous?

Class I: Nevi and other benign proliferations (83 percent) Class II: Moderately dysplastic and other low-risk lesions (8.3 percent) Class III: Melanoma in-situ and other higher-risk lesions (4.5 percent) Class IV/V: Invasive melanoma (4.1 percent)
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Can you tell the stage of melanoma from a biopsy?

These test results along with the results from your skin biopsy, complete skin exam, and physical are used to determine the stage of the melanoma. When everything that your doctor sees suggests that the cancer may have spread to a lymph node, your doctor may recommend a procedure called a sentinel lymph node biopsy.
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What organs does melanoma spread to first?

Doctors have known for decades that melanoma and many other cancer types tend to spread first into nearby lymph nodes before entering the blood and traveling to distant parts of the body.
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How quickly should melanoma be removed?

Hypothesis-based, informal guidelines recommend treatment within 4–6 weeks. In this study, median surgical intervals varied significantly between clinics and departments, but nearly all were within a 6-week frame. Key words: melanoma, surgical interval, treatment time, melanoma survival, time factors.
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How long does it take for melanoma to spread to organs?

The lesion can grow slowly for 5 to 15 years in the in situ form before becoming invasive. The exact percentage of lentigo maligna lesions that progress to invasive lentigo maligna melanoma is unknown but is estimated to be less than 30% to 50%.
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How common are abnormal moles?

Atypical moles, also called dysplastic moles, are very common. An estimated one out of every 10 Americans has at least one atypical mole. These moles are larger than common moles, with borders that are irregular and poorly defined.
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Can a mole change but not be cancerous?

Short answer: Yes. “There are normal changes that can occur in moles,” Kohen says. “For example, moles on the face can start out as brown patches, and over time as we grow older, these moles can raise up, lose color and simply become flesh-colored bumps.” Moles can lighten or darken in color, and raise or flatten.
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What stage is precancerous melanoma?

Stage 0 is known as “melanoma in situ” and is considered to be precancerous. Stage I and II melanomas are considered to be local (or localized) disease. Stage III melanoma is referred to as regional disease, and Stage IV is known as distant metastatic or advanced disease.
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What are four warning signs of melanoma?

The "ABCDE" rule is helpful in remembering the warning signs of melanoma:
  • Asymmetry. The shape of one-half of the mole does not match the other.
  • Border. The edges are ragged, notched, uneven, or blurred.
  • Color. Shades of black, brown, and tan may be present. ...
  • Diameter. ...
  • Evolving.
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Can you live a long life after stage 1 melanoma?

Prognosis for Stage 1 Melanoma: With appropriate treatment, Stage I melanoma is highly curable. There is low risk for recurrence or metastasis. The 5-year survival rate as of 2018 for local melanoma, including Stage I, is 98.4%.
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How fast does Stage 1 melanoma spread?

Melanoma can grow very quickly. It can become life-threatening in as little as 6 weeks and, if untreated, it can spread to other parts of the body. Melanoma can appear on skin not normally exposed to the sun.
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