What drugs should not be taken with prednisone?

Common medications that may interact with prednisone include:
  • antibiotics, such as clarithromycin, erythromycin, rifabutin, rifampin, or troleandomycin.
  • anticholinesterases, such as neostigmine, or pyridostigmine.
  • anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin.
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Can you take prednisolone with other medication?

Don't take anti-inflammatory painkillers (NSAIDs) like aspirin, ibuprofen or naproxen while you're taking prednisolone, unless they've been prescribed by your doctor. This type of painkiller may increase the risk of side effects on the gut, such as stomach ulceration and bleeding.
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What pain reliever can I take with prednisone?

Acetaminophen is recommended for headaches when taking prednisone.
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What OTC meds should not be taken with prednisone?

Using nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and salicylates such as aspirin may increase the risk of toxicity and gastrointestinal side effects when taken with corticosteroids.
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Does blood pressure medicine interact with prednisone?

PredniSONE may reduce the effects of lisinopril in lowering blood pressure. The interaction is most likely to occur when predniSONE is used for more than a week, since prolonged use can cause sodium and water retention.
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The Bad of Corticosteroids | Johns Hopkins



Can I take Tylenol while on prednisone?

Tylenol and prednisone are generally safe to take together and are not known to interact with each other. However, both medications can interact with other types of drugs. It's important not to take more than the recommended maximum dosage of either medication.
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Does prednisone affect your heart?

Cardiovascular Problems

Prednisone can cause irregularities in potassium, calcium and phosphate levels. This may lead to high blood pressure, heart-beat irregularities, edema (swelling) and weight gain.
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Is it OK to take ibuprofen with prednisone?

There is a moderate interaction between Ibuprofen and prednisone. It should only used together on the instruction of a Doctor, and needs to be used with caution together especially if you are prone to stomach upset including stomach ulcers and bleeding.
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How long does it take for prednisone to help inflammation?

Prednisone generally works very quickly — usually within one to four days — if the prescribed dose is adequate to reduce your particular level of inflammation. Some people notice the effects of prednisone hours after taking the first dose.
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Can I take vitamin D with prednisone?

Interactions between your drugs

No interactions were found between prednisone and Vitamin D3.
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Should I drink more water while taking prednisone?

Fluid retention can cause weight gain but as steroids are reduced, fluids will usually reduce as well, along with some of the weight gain. Drinking plenty of water and exercising can help with fluid retention.
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Can I drink coffee with prednisone?

Prednisone can affect your sense of taste and make everything seem bland, but don't load up on salt to compensate. Avoid stimulants like caffeine and nicotine that can make sleep issues worse. Cutting these out can help ease insomnia, which is a common side effect of prednisone.
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What is the difference between prednisone and prednisolone?

Official answer. The main difference between prednisone and prednisolone is that prednisone must be converted by liver enzymes to prednisolone before it can work. In people with severe liver disease, prednisolone is usually preferred.
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What can I take instead of prednisone for inflammation?

Prednisone Alternatives Compared
  • Celebrex.
  • Diclofenac.
  • Mobic.
  • Naproxen.
  • Ibuprofen.
  • Celecoxib.
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What is the downside of taking prednisone?

Common side effects of daily low dose prednisone include elevated blood pressure, swelling, changes in blood sugar, increased appetite, weight gain, insomnia, osteoporosis (thinning of bones), irregular menstrual periods, and mood changes.
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How can you tell if prednisone is working?

How to tell if the drug is working: You should experience less pain and swelling. There are also other signs that show that prednisone is effective, depending on the condition being treated. Talk with your doctor if you have questions about whether this medication is working.
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Can I take aspirin with prednisone?

aspirin predniSONE

Using aspirin together with predniSONE may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
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What are the most serious side effects of prednisone?

High blood pressure. Problems with mood swings, memory, behavior, and other psychological effects, such as confusion or delirium. Upset stomach. Weight gain, with fat deposits in your abdomen, your face and the back of your neck.
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Why does prednisone cause shortness of breath?

The most plausible explanation for the increase in respiratory rate is that prednisone may pass through the blood-brain barrier and stimulate the breathing centre. Another hypothesis was that the shortness of breath was due to hyperventilation induced by psychological effects.
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Which steroids cause heart attacks?

Among steroid users, men that currently used anabolic steroids had significantly worse heart function than past users. Authors also found that steroid users had significantly more plaque build-up in their arteries than non-users.
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Can I take Benadryl With prednisone?

Interactions between your drugs

No interactions were found between Benadryl and prednisone.
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What can you eat while taking prednisone?

While taking prednisone, you need to eat a healthy and balanced diet of foods that are:
  • low in sodium (often called salt)
  • rich in calcium and vitamin D.
  • low in calories.
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Is prednisone hard on your liver?

Corticosteroids are used widely to treat many types of disease. In general, these drugs are considered safe for the liver; however, recent reports have demonstrated that high-dose methylprednisolone (MT) may cause severe liver injury.
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How long can you take prednisone safely?

Official answer. There is no set limit on how long you can safely take prednisone.
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Why does prednisone make you feel good?

Prednisone affects areas of the brain that manage the regulation of different neurotransmitters, including serotonin and dopamine — the “feel-good” hormones. Feeling happy is a great side effect some people feel with prednisone. Other responses are more menacing, especially if you don't know what to expect.
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