What drugs should not be taken with clopidogrel?

What Drug Drug Interactions is clopidogrel involved in?

Fluoxetine and norfluoxetine (the major active metabolite) block the formation of the active metabolite of clopidogrel by strongly inhibiting CYP2C19, CYP2C9, and CYP3A4, so potentially reduce the efficacy of clopidogrel, and there is also the possibility of a pharmacodynamic interaction.

When should you not take clopidogrel?

If you have certain health conditions such as a peptic ulcer or bleeding disorder you should not take clopidogrel, unless advised by a specialist. You should use clopidogrel with caution if you have liver or kidney problems. Clopidogrel must not be given to anyone under 16 years old, unless under specialist advice.

Can I take vitamin D with clopidogrel?

No interactions were found between clopidogrel and Vitamin D3.

What time of day should you take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Clopidogrel (Plavix) uses and side effects | WATCH THIS before you take the drug!!

What painkillers can I take with clopidogrel?

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you're taking clopidogrel, unless a doctor has said it's OK. They increase the chance of bleeding. You can take paracetamol together with clopidogrel.

Can clopidogrel cause tiredness?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

What vitamins should be avoided when on blood thinners?

If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K. Blood thinners are often prescribed for people at risk for developing harmful blood clots.

Can I take multivitamins with clopidogrel?

Interactions between your drugs

No interactions were found between multivitamin and Plavix.

Can I take vitamin B12 with clopidogrel?

Interactions between your drugs

No interactions were found between clopidogrel and Vitamin B12.

Does clopidogrel affect sleep?

The organic nitrates (isosorbide) and the antiplatelet agents (acetylsalicylic acid, clopidogrel) are among the most prescribed drugs in cardiology and are not cited as causing insomnia or sleepiness.

Which is safer aspirin or clopidogrel?

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.

Does clopidogrel affect blood pressure?

You likely won't have blood pressure changes while you're taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.

What happens if you take clopidogrel and omeprazole together?

Concomitant use of omeprazole and clopidogrel was found to decrease the exposure (AUC) to clopidogrel's active metabolite by 50% and to sharply increase platelet reactivity, as a result of inhibition by omeprazole of CYP2C19, a cytochrome P450 (CYP) enzyme.

Is it safe to take omeprazole with clopidogrel?

Concomitant use of clopidogrel and omeprazole or esomeprazole is to be discouraged unless considered essential. Doctors should check whether patients who are taking clopidogrel are also buying over-the-counter omeprazole and consider whether other gastrointestinal therapies would be more suitable.

Can paracetamol be taken with clopidogrel?

It's fine to take paracetamol with clopidogrel. You can also take opioid-type painkillers such as codeine, co-codamol, tramadol or morphine alongside clopidogrel.

Can I take vitamin D with blood thinners?

No interactions were found between Vitamin D3 and warfarin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can I take vitamin C with clopidogrel?

Interactions between your drugs

No interactions were found between clopidogrel and Vitamin C.

Can I take fish oil with clopidogrel?

In conclusion, high-dose fish oil is safe in combination with aspirin and clopidogrel and does not increase the risk of bleeding compared with that seen with aspirin and clopidogrel alone.

Can you drink orange juice while on blood thinners?

Grapefruit mostly impacts blood-thinning medications such as Apixaban (Eliquis), Rivaroxaban (Xarelto), Clopidogrel (Plavix) and Ticagrelor (Brilinta). If you're taking one of these medications and crave that citrus flavor, Dr. Crites suggests switching to orange juice.

Do blood thinners cause cold hands and feet?

A blood thinner works by slowing or impairing the blood's ability to clot, Dr. Andersen said, and will not make someone feel colder.

Can you take vitamin C with blood thinners?

In recent follow-up studies, no effect was found with doses of vitamin C up to 1,000 mg per day. However, if you take warfarin or another blood thinner, talk to your doctor before taking vitamin C or any other supplement.

Does clopidogrel cause leg cramps?

It frequently occurs in the legs and often causes claudication or pain in the legs upon walking. Plavix is used to reduce the risk of heart attacks and strokes in these patients.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel.

Does clopidogrel make you gain weight?

Weight changes, including weight loss, are not commonly seen with Plavix. However, Plavix has been shown to cause loss of taste in a few individuals within the first two to eight weeks of taking the medication. Patients who lose their sense of taste may also have decreased appetite, leading to weight loss.