What drugs should be avoided in heart failure?

Heart failure medicine dos and don'ts: What to avoid
  • Non-steroidal anti-inflammatory drugs (NSAIDS). ...
  • Cold and cough medicines with pseudoephedrine or phenylephrine. ...
  • Alka-Seltzer® – this has too much sodium (salt).
  • Calcium channel blockers such as diltiazem (Cardizem) or verapamil (Calan, Verelan).
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What drugs make heart failure worse?

Drugs that can exacerbate heart failure should be avoided, such as nonsteroidal anti-inflammatory drugs (NSAIDs), calcium channel blockers (CCBs), and most antiarrhythmic drugs (except class III).
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Which of the following drugs is contraindicated in a patient with heart failure?

Drugs like nonsteroidal anti-inflammatory drugs, antiarrhythmic agents, and calcium channel blockers should be avoided in patients with congestive heart failure as they are known to have negative or deleterious effects on cardiac contractility, the neurohormonal system, or may cause sodium retention.
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Which antihypertensive is contraindicated in heart failure?

Nondihyropyridine calcium channel blockers (diltiazem and verapamil) are contraindicated in patients with HF (except in HFNEF) because of their negative inotropic effects.
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Which one of the following drugs should be avoided in patients with cardiovascular disease?

Medications to Avoid in patients with Heart Failure
  • Non-dihydro Calcium Channel Blockers (CCB):
  • Nonsteroidal Anti-Inflammatory Drugs (NSAID) : Diclofenac , indomethacin , ketorolac ..etc AND COX-2 selective inhibitors (Celecoxib) :
  • Tumor Necrosis Factor alpha inhibitors (Anti-TNF-alpha):
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Heart failure: Avoid these medications



Are beta blockers contraindicated in heart failure?

Beta blockers should not be administered to patients with heart failure who have bradycardia, heart block or hemodynamic instability. Patients hospitalized for heart failure may receive beta blockers only after they have been stabilized.
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What drugs prolong life in heart failure?

β-Blockers (carvedilol, metoprolol CR/XL, and bisoprolol) improve survival in stable patients with CHF who have no contraindications and can tolerate the drugs.
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Can you use amlodipine in heart failure?

Taken together, these observations indicate that amlodipine can be used with relative safety in patients with severe heart failure — an important finding, since angina and hypertension can be difficult to treat in patients with left ventricular dysfunction.
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Why is metformin contraindicated in heart failure?

The use of metformin was considered a contraindication in heart failure patients because of the potential risk of lactic acidosis; however, more recent evidence has shown that this should no longer be the case.
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Why are NSAIDs contraindicated in heart failure?

Current practice guidelines for heart failure therapy recommend avoiding non-steroidal anti-inflammatory drugs (NSAIDs), because they can cause sodium retention and vasoconstriction and can reduce the effectiveness and increase the toxicity of ACE inhibitors and diuretics.
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What drugs are cardiotoxic?

The most common chemotherapy drugs related to cardio-toxicity include:
  • 5-fluorouracil (Adrucil)
  • Paclitaxel (Taxol)
  • Anthracyclines (a class of drugs)
  • Targeted therapies: such as monoclonal antibodies and tyrosine kinase inhibitors.
  • Some Leukemia drugs.
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Which drug is best for a patient with type 2 diabetes and heart failure?

Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai.
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Can you give metformin in heart failure?

A systematic review of observational studies indicates that metformin can be safely used in patients with diabetes mellitus and HF, even in heart failure with reduced left ventricular ejection fraction or chronic kidney failure.
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Is metformin safe for heart failure patients?

Current guidelines from the American Diabetes Association state the use of metformin is contraindicated in patients treated for congestive heart failure.
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Which calcium channel blocker is contraindicated in heart failure?

Calcium channel blockers generally should not be used if you have heart failure due to systolic dysfunction. Calcium channel blockers include: Norvasc. Plendil.
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Can amlodipine make heart failure worse?

This medicine may cause worsening of angina (chest pain) or a heart attack in certain patients with severe heart or blood vessel disease.
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Why is calcium channel blocker contraindicated in heart failure?

Although it has been suggested that calcium channel blocking agents may be utilized as vasodilators in patients with congestive heart failure, these agents also have the potential to cause a deterioration in cardiac function because of their negative inotropic actions.
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What is the drug of first choice in heart failure?

Diuretics improve symptoms and exercise capacity and probably survival. They are the drug of first choice in acute and chronic heart failure. Potassium supplementation is necessary.
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What is the drug of choice for heart failure?

There are many different types of diuretic, but the most widely used for heart failure are furosemide (also called frusemide) and bumetanide. Possible side effects of diuretics include dehydration and reduced levels of sodium and potassium in the blood.
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What is the drug of choice in CHF?

Digoxin has been the traditional first drug of choice for CHF, but with protracted controversy about its efficacy and safety. It is hope that new agents as vesnarione, and ibopamine may improve contractility without having adverse consequences.
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Why is propranolol contraindicated in heart failure?

Propranolol as with other beta-blockers, has negative inotropic effects, and is therefore contraindicated in uncontrolled heart failure.
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Why do beta-blockers worsen heart failure?

Beta-blockers are drugs that can slow your heart rate and keep it from overworking. They also can stop your heart from responding to stress hormones, such as adrenaline.
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Why is metoprolol used in heart failure?

In addition, metoprolol is used to treat patients with heart failure. This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure.
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Can you take amlodipine and metformin?

The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Metformin.
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Is glimepiride safe for heart patients?

"Multiple studies have shown that sulfonylurea drugs -- glipizide, glyburide and glimepiride -- increasedcardiovascular mortality, heart attack and congestive heart failure" she said, "so sulfonylureas should be avoided in all cardiac patients."
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