What drugs interfere with levothyroxine?

Drugs that Impair Levothyroxine Absorption
A number of drugs have been shown to impair the absorption of levothyroxine; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat.
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What medications should you not take with levothyroxine?

Some medicines should not be taken at the same time of day as levothyroxine as they can reduce the amount of levothyroxine your body takes in, including:
  • antacids.
  • calcium salts.
  • iron salts.
  • orlistat, a medicine used for weight loss.
  • sucralfate, a medicine used to treat stomach ulcers.
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Can I take levothyroxine with my other medications?

Ideally, levothyroxine should be the only medication taken at bedtime. Just as with morning dosing, it is best to avoid co-administration with other medications such as statins, blood pressure drugs, and metformin.
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What supplements interfere with thyroid medication?

Vitamins and supplements

“You should also avoid any drugs or supplements that contain iron, calcium, or magnesium for at least four hours after taking your thyroid medications,” says Dr. Jaiswal. That also includes multivitamins that contain these minerals.
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Does vitamin D interfere with levothyroxine?

No interactions were found between levothyroxine and Vitamin D3.
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How To Take Levothyroxine Properly | Best Way To Take Thyroid Medication | When To Take Synthroid



Does vitamin D affect thyroid medicine?

This effect was more pronounced for thyroid peroxidase than for thyroglobulin antibodies and correlated with their baseline titers. Conclusions: Vitamin D preparations may reduce thyroid autoimmunity in levothyroxine-treated women with Hashimoto's thyroiditis and normal vitamin D status.
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How long after taking levothyroxine Can I take other meds?

Aim to take levothyroxine at least 2 hours before your other medications, or at least 4 hours after.
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Why do you have to drink a full glass of water with levothyroxine?

The Levoxyl-branded tablet may rapidly swell and disintegrate, and cause choking or gagging if it becomes stuck in your throat. Take with a full glass of water, but talk with your doctor should you have difficulty swallowing it.
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Is it better to take levothyroxine at night or in the morning?

There is consensus that levothyroxine should be taken in the morning on an empty stomach. A pilot study showed that levothyroxine intake at bedtime significantly decreased thyrotropin levels and increased free thyroxine and total triiodothyronine levels.
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Does caffeine affect levothyroxine?

Summary. Caffeine in coffee and other caffeinated beverages can affect the absorption of the thyroid drug levothyroxine by making the drug pass through your gut too quickly. This can cause your T4 hormone levels to drop or fluctuate.
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Can you drink coffee after taking levothyroxine?

8) You take your Synthroid or levothyroxine with coffee

After taking your thyroid med, you should also wait at least an hour before drinking coffee. Hope this helps.
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What are the long term side effects of levothyroxine?

The long-term effects of thyroid medication include weight fluctuations, sensitivity to heat, joint pain, changes to your menstrual cycle, and possibly even autoimmune dysfunction.
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Why was levothyroxine taken off the market?

FDA Drug safety recall warning

This is due to the medication having less active drug (levothyroxine) than it is supposed to. Taking these tablets can lead to symptoms of hypothyroidism, such as fatigue, constipation, hair loss, and depression.
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Is coffee good for thyroid?

Coffee: Time Your First Cup Carefully in the Morning

Per a study in the journal Thyroid, caffeine has been found to block absorption of thyroid hormone replacement. "People who were taking their thyroid medication with their morning coffee had uncontrollable thyroid levels, and we couldn't figure it out," says Dr. Lee.
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What is considered a dangerously high TSH level?

A TSH over 10 mIU/L has been linked to an increased risk of coronary heart disease and heart failure, which is why you'll probably want to seek treatment if your TSH is close to (but still under) that upper limit.
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Is 25 mcg levothyroxine a lot?

There are two strategies for initiating levothyroxine in healthy adults younger than 65 years: low-dose (50 mcg) and full-dose (1.6 to 1.7 mcg per kg). Traditionally, lower starting doses of 25 to 50 mcg per day are recommended for patients 65 years and older or who have ischemic heart disease.
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What is a thyroid storm?

Thyroid storm is a very rare, but life-threatening condition of the thyroid gland that develops in cases of untreated thyrotoxicosis (hyperthyroidism, or overactive thyroid). The thyroid gland is located in the neck, just above where your collarbones meet in the middle.
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Is underactive thyroid an autoimmune disease?

Hypothyroidism may be due to a number of factors, including: Autoimmune disease. The most common cause of hypothyroidism is an autoimmune disorder known as Hashimoto's thyroiditis. Autoimmune disorders occur when your immune system produces antibodies that attack your own tissues.
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Can I take Tylenol and levothyroxine together?

Interactions between your drugs

No interactions were found between levothyroxine and Tylenol.
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Can I sleep after taking thyroid medication?

Official answer. Many people who take medication to treat an underactive thyroid gland are told to do so in the morning on an empty stomach, but there are times that it may make sense to take the prescribed medication at night before bed.
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How do you take levothyroxine at night?

However, the American Thyroid Association recommends that, if possible, levothyroxine be consistently taken either 60 minutes before breakfast or at bedtime (3 or more hours after the evening meal), for optimal, consistent absorption.
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Is it OK to take multivitamins with thyroid medication?

Multivitamins. Like hormones, minerals like iron and calcium can bind to thyroid hormone and inhibit absorption. A good rule of thumb: “Take your thyroid hormone first thing in the morning, on an empty stomach, and take multivitamins and other supplements at lunch, at least 4 hours later,” suggests Levy.
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Which vitamin is not good for thyroid?

Should people with thyroid problems avoid these supplements? Iodine: Yes. Avoid it as a supplement whether you have hyperthyroidism or hypothyroidism. The effect of iodine supplements can vary by person, causing the thyroid to produce either too much or too little hormone.
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What supplements to avoid with hypothyroidism?

According to the Mayo Clinic, supplements such as calcium, iron, multivitamins containing iron, and antacids containing magnesium or aluminum can potentially have interactions with thyroid medications. They should be taken several hours before or after your thyroid medication to avoid an interaction.
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Can levothyroxine cause dementia?

Higher total and free thyroxine levels were associated with an increased risk of dementia and AD (age and sex adjusted hazard ratio (95% confidence interval) per SD increase in free thyroxine: 1.21 (1.04; 1.40) and 1.31 (1.14; 1.51) respectively).
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