What does abnormal prolactin mean?

If prolactin levels are higher than normal, it often means there is a type of tumor of the pituitary gland, known as a prolactinoma. This tumor makes the gland produce too much prolactin. Excess prolactin can cause the production of breast milk in men and in women who are not pregnant or breastfeeding.
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What causes abnormal prolactin levels?

Causes of Abnormal Prolactin Levels

Prolactinoma (a benign tumor in your pituitary gland that produces too much prolactin) Diseases affecting the hypothalamus(the part of the brain that controls the pituitary gland) Anorexia(an eating disorder) Drugs that are used to treat depression, psychosis, and high blood pressure.
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Can stress cause high prolactin levels?

Prolactin levels also get higher during times of physical or emotional stress. Many medicines can cause prolactin levels to go up. Tumors of the pituitary gland can sometimes cause prolactin to be made. A damaged pituitary gland may not be able to make normal amounts of prolactin so levels will be lower.
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What is the cause of high prolactin in a woman?

Certain medications can also cause higher prolactin levels. Symptoms of high prolactin include sexual and menstrual problems, infertility, breast milk leakage, and others. The condition can be diagnosed with a blood test. In some cases, an MRI may be needed.
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What does prolactin level tell you?

Prolactin is a hormone that's responsible for lactation, certain breast tissue development and milk production. Higher-than-normal levels of prolactin in your blood can cause certain symptoms, such as irregular periods, infertility and erectile dysfunction.
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Hyperprolactinemia (High Prolactin Levels) | Causes, Signs



Does prolactin cause weight gain?

High levels of prolactin can also result in weight gain and neuropsychological disturbances.
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Can you have high prolactin and not have a tumor?

“Patients with high prolactin levels who have few or no symptoms and no demonstrable pituitary tumor may not need treatment, but infertile or pregnant patients, and individuals with bothersome symptoms require specialized treatment depending on the cause of their condition,” Melmed said in a press release.
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Does high prolactin make you tired?

Rarely, the prolactinoma may press on the rest of the pituitary gland, stopping it from producing other hormones. This can cause symptoms such as tiredness, fainting, low blood pressure, low blood sugar or collapse.
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What is the best treatment for high prolactin?

Dopamine agonists such as bromocriptine (Parlodel and Cycloset) are the most common treatment for high levels of prolactin. These medications help the brain produce dopamine to control high prolactin levels. They can also shrink prolactinoma tumors. Your doctor may recommend that you take cabergoline.
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Can high prolactin be cured?

Medications. Oral medications known as dopamine agonists are generally used to treat a prolactinoma. These drugs mimic the effects of dopamine — the brain chemical that controls how much prolactin is made. Dopamine agonists can decrease the production of prolactin and shrink the size of the tumor.
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Why is my prolactin high if I'm not pregnant?

If prolactin levels are higher than normal, it often means there is a type of tumor of the pituitary gland, known as a prolactinoma. This tumor makes the gland produce too much prolactin. Excess prolactin can cause the production of breast milk in men and in women who are not pregnant or breastfeeding.
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What level of prolactin indicates a tumor?

Prolactin levels are usually directly proportionate to the size of tumor ranging from below 200 ng/ml with less than 1 cm, 200 ng/ml to 1000 ng/ml with 1 cm to 2 cm and more than 1000 ng/ml with tumor sized more than 2 cm in diameter.
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Does PCOS cause high prolactin?

Some women with PCOS do have elevated prolactin levels, typically falling within the 25-40 ng/ml range. ANDRO is a hormone that is produced by the ovaries and adrenal glands. Sometimes high levels of this hormone can affect estrogen and testosterone levels. Normal ANDRO levels are between 0.7 3.1 ng/ml.
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What happens if a pituitary tumor goes untreated?

Most pituitary tumors are curable, but if left untreated, they can lead to serious complications such as complete vision loss.
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What does prolactin do in females?

Prolactin is a hormone released by the pituitary gland. The pituitary is a small gland at the base of the brain. It regulates the body's balance of many hormones. Prolactin stimulates breast development and milk production in women.
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What are the signs and symptoms of hyperprolactinemia?

What are the symptoms of hyperprolactinemia?
  • Milky nipple discharge.
  • Milk production when not pregnant or breastfeeding.
  • Menstrual irregularities.
  • Vaginal dryness, causing painful intercourse.
  • Fertility problems.
  • Headaches and visual problems (both of these are less common)
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How is prolactinoma diagnosed?

How do doctors diagnose prolactinomas? Blood test. The prolactin blood test link will measure the level of prolactin in your blood. If the level is too high, your doctor will order an imaging test to detect a possible tumor.
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Does high prolactin cause hair loss?

High prolactin levels can cause hair loss in a pattern similar to female androgenetic alopecia. It does this by interfering with normal ovarian production of estrogen.
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Can you lower prolactin naturally?

Foods that lower prolactin levels are generally high in zinc; think shellfish, beef, turkey and beans. It's also important to get plenty of B6, so foods like potatoes, bananas, wild salmon, chicken and spinach can help boost those vitamin levels.
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Is a prolactinoma serious?

A prolactinoma isn't life-threatening. But it can cause vision difficulties, infertility and other problems. Prolactinoma is the most common type of hormone-producing tumor that can develop in the pituitary gland.
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Does high prolactin mean tumor?

Prolactin affects the mammary glands and helps women make breast milk. Sometimes, a tumor grows on the pituitary gland and makes too much prolactin. This kind of tumor is called a prolactinoma. It's the most common type of pituitary tumor and is most often benign, which means it's not cancer.
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What are the symptoms of a tumor in the pituitary gland?

Pituitary tumors that make hormones (functioning) can cause a variety of signs and symptoms depending on the hormone they produce.
...
Signs and symptoms include:
  • Nausea and vomiting.
  • Weakness.
  • Feeling cold.
  • Less frequent or no menstrual periods.
  • Sexual dysfunction.
  • Increased amount of urine.
  • Unintended weight loss or gain.
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Is High prolactin common?

What is hyperprolactinemia? Hyperprolactinemia is a condition of too much prolactin in the blood of women who are not pregnant and in men. Hyperprolactinemia is relatively common in women. About a third of women in their childbearing years with irregular periods but normal ovaries have hyperprolactinemia.
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Can prolactinoma cause death?

Mortality is unlikely, although a study by Soto-Pedre et al (discussed below) did report increased mortality depending on the cause of hyperprolactinemia. In cases where the condition is due to a large prolactin-secreting tumor, local mass effect can lead to significant morbidity.
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What are the first signs of PCOS?

Common symptoms of PCOS include:
  • irregular periods or no periods at all.
  • difficulty getting pregnant (because of irregular ovulation or failure to ovulate)
  • excessive hair growth (hirsutism) – usually on the face, chest, back or buttocks.
  • weight gain.
  • thinning hair and hair loss from the head.
  • oily skin or acne.
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