What doctor do you see for white matter disease?

A radiologist, particularly a neuroradiologist, has expertise in what the brain should look like on an MRI. When evaluating for white matter disease, the radiologist will be looking for abnormal signal in the brain tissue.

What kind of doctor treats white matter disease?

Healthcare providers such as neurologists and neuro-radiologists are often able to distinguish white matter disease lesions from other causes of lesions with MRI based on where they're located in your brain. Sometimes additional testing is necessary to help determine the cause of the white matter lesions on your MRI.

How long can you live with moderate white matter disease?

Within 2 years, children can develop gait and posture problems, as well as blindness and paralysis. It is not possible to stop disease progression, and it is typically fatal within 6 months to 4 years of symptom onset.

How do you know if you have white matter disease?

Advances in medical imaging have made white matter disease easier to spot. A magnetic resonance imaging (MRI) test, which takes pictures of the inside of your brain, can show any damage. Changes to white matter will show up super-bright white (your doctor may call this "hyperintense") on an MRI scan.

Is white matter disease a neurological disorder?

White matter disease is a progressive disorder caused by age-related decline in the part of the nerves (the white matter) that connect different areas of brain to each other and to the spinal cord.

Severity of White Matter Hyperintensities

Who treats leukodystrophy?

At Mayo Clinic, a team of doctors trained in nervous system conditions (neurologists), genetic disorders (medical geneticists) and other specialties work together as a team to care for people with metachromatic leukodystrophy.

Does white matter disease cause fatigue?

Brain white matter (WM), and more specifically neuronal connectivity, is thought to perform a crucial role in the central processing of fatigue [1]. In diseases of the WM, such as multiple sclerosis (MS), persisting fatigue is a common disabling complication [2].

Is white matter disease painful?

In addition, white matter hyperintensities (WMH), for example in the spinothalamic tract, also referred to as the anterolateral pathway, may lead to an increase in pain experience; this type of pain is paraphrased as deafferentiation pain.

What happens when you have too much white matter in the brain?

Originally, white matter disease was considered a normal, age-related change. But over the last decade, medical experts have come to understand that the presence of large areas of disease in the white matter of the brain are associated with cognitive decline and dementia in patients.

Is white matter disease the same as small vessel disease?

Now, perhaps the best technical term for what I'm referring to is “cerebral small vessel disease.” But many other synonyms are used by the medical community — especially in radiology reports. They include: Small vessel ischemic disease. White matter disease.

Does white matter disease cause memory loss?

Unlike Alzheimer's disease which shrinks the hippocampus causing progressive memory loss, white matter disease is a more diffuse mind-robbing condition that targets small blood vessels deep within the brain's white matter.

Does white matter disease cause headaches?

Patients with extensive white matter hyperintensities are likely to have tension-type headaches or to have headaches develop during middle age, according to results published in Cephalagia. Currently, there are no established treatments or strategies for managing white matter hyperintensities.

What does white matter on brain MRI mean?

White matter disease is commonly detected on brain MRI of aging individuals as white matter hyperintensities (WMH), or 'leukoaraiosis.” Over the years it has become increasingly clear that the presence and extent of WMH is a radiographic marker of small cerebral vessel disease and an important predictor of the life- ...

How do you get rid of white matter in the brain?

White matter disease doesn't have a cure, but there are treatments that can help manage your symptoms. The primary treatment is physical therapy. Physical therapy can help with any balance and walking difficulties you may develop.

What disease does a neurologist treat?

Neurologists are specialists who treat diseases of the brain and spinal cord, peripheral nerves and muscles. Neurological conditions include epilepsy, stroke, multiple sclerosis (MS) and Parkinson's disease. Dr.

Is white matter disease the same as vascular dementia?

White matter disease (WMD), also called multiple cerebral infarction, is regarded as the common cause of “mild” dementia in the elderly, and if dementia is the main problem, it is called a vascular dementia (Roman et al., 1993).

What does leukoaraiosis mean?

The term leukoaraiosis refers to neuroimaging abnormalities of the white matter, which appear as hypodense or hyperintense areas, are located predominantly in the periventricular area, and are found especially in older people [1,2].

Is white matter on the brain dementia?

White matter has a legitimate position in the study of dementia. The neuropathology of white matter disorders is typically diffuse or widespread, thus disrupting many networks simultaneously and producing a multi-domain syndrome that merits the term dementia.

Can stress cause white matter?

Increased exposures to stressful events are associated with a corresponding increase in the progression of white matter hyperintensities.

Can white matter lesions in the brain be nothing?

Studies have found that white matter lesions appear in some degree on brain scans of most older adults but less often in younger people. White matter lesions are among the most common incidental findings—which means the lesions have no clinical significance—on brain scans of people of any age.

Does everyone have white matter in the brain?

See other articles in PMC that cite the published article. “Gray matter” is only one of two types of brain tissue; the other “white matter” is rarely mentioned. Yet white matter makes up half the human brain and has not been thought to be important in cognition or learning outside the context of pathology.

Does white matter increase with age?

Age-correlated studies reveal that the changes in white matter may be much higher than those of gray matter (Miller et al., 1980). Upto 40 years of age, the white matter volume increases and is closely related to the formation of the myelin sheath (Courchesne et al., 2000; Bartzokis, 2004).

What triggers leukodystrophy?

Leukodystrophy is the result of changes (mutations) to genes. These genes control the growth or function of myelin. Without this protective covering, nerve cells don't work correctly. Most leukodystrophies come from parents passing the genes to their children (inherited).

How is MLD diagnosed?

Clinical Testing and Work-Up

An MRI can confirm a diagnosis of MLD. An MRI shows imaging of a person's brain and can show the presence and absence of myelin. There is a classic pattern of myelin loss in the brains of individuals affected by MLD. As the disease progresses, imaging shows accumulating injury to the brain.

What is the life expectancy of someone with leukodystrophy?

The prognosis for MLD is poor. Most children within the infantile form die by age 5. Symptoms of the juvenile form progress with death occurring 10 to 20 years following onset. Those persons affected by the adult form typically die withing 6 to 14 years following onset of symptoms.