What causes oligodontia?

Possible causes of oligodontia include viral disease during pregnancy, genetic predisposition, metabolic imbalances, developmental abnormalities and environmental factors. Autosomal dominant mutations in PAX9 and MSX1 have been found in patients with molar non-syndromic oligodontia.
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What type of mutation causes oligodontia?

WNT10A mutations are the most commonly reported in the genetic etiology for syndromic oligodontia and PAX9 mutations are the most commonly reported genetic etiology for isolated oligodontia. Oligodontia is not only a disorder of missing teeth but also a clinical sign of a potentially complex systemic condition.
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What syndromes are associated with oligodontia?

Oligodontia can occur in association with various genetic syndromes, like ectodermal dysplasia, Van Der Woude syndrome, Down syndrome and Reiger syndrome or as a nonsyndromic isolated familial trait, or as an infrequent finding.
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Is oligodontia hereditary?

Oligodontia is a dental abnormality in which the patient is missing teeth. It is a hereditary disorder characterized by agenesis of more than 6 pri- mary/permanent teeth, excluding the wisdom teeth.
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Does oligodontia include wisdom teeth?

Oligodontia is defined by the lack of at least six definitive teeth, excluding wisdom teeth, resulting from hypodevelopment of teeth germs. The pathology can be isolated, or can be associated with other ectodermal abnormalities and syndromes such as ectodermal dysplasia, cleft lip and palate.
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Oligodontia



How is oligodontia treated?

Treatment of oligodontia requires a multidisciplinary approach. Prosthetic treatment includes removable partial dentures, fixed partial dentures and over dentures. Osseointegrated dental implants are also possible when there is adequate bone height as they offer a more stable, long-term solution.
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Is oligodontia a disability?

Conclusions: Oligodontia is a heterogeneous condition. Patients with oligodontia can be classified as having three different types according to the extent of their disability and the complexity of their prosthodontic requirements.
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How common is missing permanent teeth?

Researchers estimate that as many as 20 percent of adults are born with at least one missing tooth, making hypodontia one of the most common developmental oral health conditions. Most individuals are missing only one or two permanent teeth, with very few missing more than six.
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Is missing teeth a disability?

Therefore, an individual should be considered to have a dental disability if orofacial pain, infection, or pathological condition and/or lack of functional dentition affect nutritional intake, growth and development, or participation in life activities.
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What causes tooth agenesis?

Although dental agenesis is occasionally caused by environmental factors, such as infection (e.g. rubella), various kinds of trauma of the dental region, multi-reagent chemotherapy or radiotherapy, or disturbances in jaw innervations, in a majority of cases, hypodontia has genetic causes (1,6).
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Is anodontia hereditary?

Anodontia is an inherited genetic defect. The exact genes involved are unknown. However, Anodontia is usually associated with ectodermal dysplasia. Ectodermal dysplasia is not one disorder but a group of closely related hereditary conditions that affect the hair, nails, skin, and sweat glands.
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Is missing permanent teeth genetic?

Congenitally missing teeth are teeth that never appear and are not trapped in the gums – they just do not exist in some people! The condition, which usually affects the lateral incisors and the second premolars, is often a harmless genetic trait passed down from parents to their children.
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How common is anodontia?

The prevalence of anodontia is unknown but it is a very rare disorder. Anodontia occurs in less than 2-8% of the general population in regards to permanent teeth and 0.1-0.7% in primary teeth.
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What is ectodermal dysplasia caused by?

The different types of ectodermal dysplasia are caused by the mutation or deletion of certain genes located on different chromosomes. Because ectodermal dysplasias are caused by a genetic defect they may be inherited or passed down the family line.
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What causes severe hypodontia?

Hypodontia is usually the result of a problem with the band of tissue under the gums (dental lamina) where the teeth form. The most common cause of these problems is heredity or family history. A mutation of one of the specific genes which help form the dental lamina properly can lead to hypodontia.
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Why are some babies born without teeth?

Genetics: Several genetic disorders can trigger a delay in tooth eruption, such as Down syndrome, Cleidocranial dysostosis, and Apert syndrome. Some rare genetic abnormalities can cause poorly formed teeth and late tooth appearances, such as amelogenesis imperfecta and regional odontodysplasia.
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What disorders are missing teeth?

Anodontia is a genetic disorder defined as the absence of all teeth. It usually occurs as part of a syndrome that includes other abnormalities. Also rare but more common than anodontia are hypodontia and oligodontia.
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What is a ghost tooth?

Teeth in a region or quadrant of maxilla or mandible are affected to the extent that they exhibit short roots, wide open apical foramen and large pulp chamber, the thinness and poor mineralisation qualities of th enamel and dentine layers have given rise to a faint radiolucent image, hence the term "Ghost teeth".
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Which tooth is most often congenitally missing?

Prevalence of congenitally missing teeth was totally 45.7% and 34.8% for third molars. The most frequent congenitally missing teeth was mandibular second premolars (23.34%) followed by maxillary second premolars (22.02%).
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When should I worry about permanent teeth not coming in?

If it has been six months or longer since your child has lost a tooth and there is no sign of a permanent tooth erupting, it is strongly recommended to visit their pediatric dentist.
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What happens if you are missing a permanent tooth?

Common Solutions for Dealing With Missing Permanent Teeth. There are three common solutions for missing adult teeth in children. To start, you may be able to preserve the primary or baby tooth if it has not already fallen out. You can also replace the missing tooth structure using an implant or dental bridge.
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What is the second tooth in hypodontia?

The second premolars – these are the teeth right in front of your molars. One may sometimes be removed during braces treatment, but if your child is missing this permanent tooth, chances are it's due to hypodontia.
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Are peg laterals hereditary?

Peg-shaped teeth are a hereditary dental disorder called microdontia, a condition where one or more teeth appear smaller than average (microdontia) [1]. In general, the most common teeth affected are the upper lateral incisors or sometimes third molars.
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What is pseudo anodontia?

Pseudoanodontia is a descriptive term that indicates clinical but not radiographic absence of teeth that should normally be present in the oral cavity for the patient's dental and chronologic age.
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Can you claim dental on VA disability?

If you're a Veteran, you may be able to get VA dental care. Dental benefits are not the same as other VA medical benefits.
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