What cancers cause high protein in blood?

Possible Causes
Viral infections such as hepatitis B, hepatitis C or HIV/AIDS. Blood cancers such as multiple myeloma or certain types of lymphoma. Severe liver or kidney disease.
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What kind of cancer causes high protein in the blood?

In multiple myeloma, cancerous plasma cells accumulate in the bone marrow and crowd out healthy blood cells. Rather than produce helpful antibodies, the cancer cells produce abnormal proteins that can cause complications.
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What is usually the first early symptom of multiple myeloma?

Multiple myeloma causes many symptoms, but bone pain often is the first symptom people notice. Other symptoms include: Weakness in your arms and legs and/or a sensation of numbness in your arms and legs. Multiple myeloma can affect the bones in your spine, causing them to collapse and press on your spinal cord.
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Should I be worried about high protein in blood?

A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally. If the result of a total protein test is abnormal, further tests will be needed to identify which proteins are too high or too low.
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What diseases causes high protein in blood?

Possible causes of high blood protein include:
  • Amyloidosis (buildup of abnormal proteins in your organs)
  • Dehydration.
  • Hepatitis B.
  • Hepatitis C.
  • HIV/AIDS.
  • Monoclonal gammopathy of undetermined significance (MGUS)
  • Multiple myeloma.
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What does high protein in blood indicate?

High blood protein is an increase in the concentration of protein in the bloodstream. The medical term for high blood protein is hyperproteinemia. High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own.
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What disease or illness is associated with protein?

Protein misfolding is believed to be the primary cause of Alzheimer's disease, Parkinson's disease, Huntington's disease, Creutzfeldt-Jakob disease, cystic fibrosis, Gaucher's disease and many other degenerative and neurodegenerative disorders.
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How do you fix high protein in your blood?

Your high blood protein levels may simply be due to dehydration. Blood is made up of mostly water. When you don't drink enough fluids, the components of your blood become more concentrated, leading to a falsely elevated protein level. Drinking more water easily fixes the problem.
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Can high protein in blood be cured?

There is no cure for amyloidosis. Treatment of an underlying illness - if there is one - can cause the amyloidosis to go away. Drugs and diet can help manage symptoms and help prevent the production of more of the protein.
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How high is protein in multiple myeloma?

Hematological profile of patients with multiple myeloma

Hyperproteinemia (> 9 gm/dl) was seen in 30% and hypoproteinemia (< 6 gm/dl) in 10% cases. A/G ratio was decreased (< 0.80) in 54.2% and high (>2) in 4.4%. In 30% of patients with normal total proteins, A/G ratio was low.
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What are the red flags for multiple myeloma?

High blood levels of calcium

Extreme thirst, leading to drinking a lot. Urinating (peeing) a lot. Dehydration. Kidney problems and even kidney failure.
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What is the hallmark symptom of multiple myeloma?

The hallmark symptom of multiple myeloma is bone pain. It often occurs in the back, the hips, and sometimes the skull. Some patients may experience pain that is worse at night, which disrupts their sleep. When you have multiple myeloma, your bones may easily break.
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When should I suspect myeloma?

Signs and symptoms

In the early stages, myeloma may not cause any symptoms. It's often only suspected or diagnosed after a routine blood or urine test. However, myeloma will eventually cause a wide range of problems, including: a persistent dull ache or specific areas of tenderness in your bones.
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Does high protein mean cancer?

No relation between higher protein intake with all-cause mortality, cancer-related mortality, or cardiovascular mortality overall. A small increase in risk was seen when looking only at people between the ages of 50-65.
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What cancers are related to protein?

Examples of up-regulated proteins in cancer include the epidermal growth factor receptor 2 (HER2) and the vascular endothelial growth factor (VEGF). HER2 is up-regulated in several cancer types, including breast (1), gastroesophageal (2), and non-small-cell lung cancers (3), making it an effective drug target (4).
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What is a protein cancer marker?

Tumor markers have traditionally been proteins or other substances that are made at higher amounts by cancer cells than normal cells. These can be found in the blood, urine, stool, tumors, or other tissues or bodily fluids of some patients with cancer.
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What are the signs of too much protein?

Symptoms associated with too much protein include:
  • intestinal discomfort and indigestion.
  • dehydration.
  • unexplained exhaustion.
  • nausea.
  • irritability.
  • headache.
  • diarrhea.
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What are the two most common diseases that result from protein deficiencies?

There are two main syndromes associated with protein deficiencies: Kwashiorkor and Marasmus. Kwashiorkor affects millions of children worldwide. When it was first described in 1935, more than 90 percent of children with Kwashiorkor died.
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What is the most common cause of elevated total protein?

Higher-than-normal levels may be due to: Chronic inflammation or infection, including HIV and hepatitis B or C. Multiple myeloma. Waldenstrom disease.
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Is 8.5 protein in blood high?

The normal range is 6.0 to 8.3 grams per deciliter (g/dL) or 60 to 83 g/L. Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.
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What is first stage myeloma?

Stage 1 (or stage I) multiple myeloma is the least advanced stage. People with stage 1 myeloma have few myeloma cells in the body. The cancer cells have not yet spread very far or caused as much damage as in other stages.
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What test confirms multiple myeloma?

A bone marrow biopsy is usually needed to confirm multiple myeloma. A needle is used to take a small sample of bone marrow (where all the blood cells are made) from one of your bones, usually the pelvis. A small sample of bone may also be removed.
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What conditions are mistaken for myeloma?

Myeloma shares some similar features and symptoms with other blood disorders, including:
  • Monoclonal gammopathy.
  • Waldenström macroglobulinemia (WM)
  • Primary amyloidosis.
  • Heavy chain disease.
  • Light chain deposition disease (LCDD)
  • Plasma cell leukemia (PCL)
  • POEMS syndrome.
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Where does myeloma pain start?

Multiple myeloma can cause pain in affected bones – usually the back, ribs or hips. The pain is frequently a persistent dull ache, which may be made worse by movement.
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