What cancers cause granuloma annulare?

Which malignancies have been associated with granuloma annulare?
  • Non-Hodgkin lymphoma.
  • Hodgkin lymphoma.
  • Acute myelogenous leukemia.
  • Chronic lymphocytic leukemia.
  • Myelomonocytic leukemia.
  • Large granular lymphocytic leukemia.
  • Myelodysplastic syndrome.
  • T-cell lymphoma.
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What cancer is related to granuloma annulare?

Generalized granuloma annulare can be associated with breast cancer. Atypical granuloma annulare especially in older patients should alert physicians to the possibility of an occult malignancy.
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Is granuloma annulare a symptom of cancer?

Granuloma annulare is a benign (not cancer), often chronic (long-lasting) skin disorder in which inflammation in the skin causes a raised, discolored rash or lumps under the skin.
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What autoimmune disease causes granuloma annulare?

Granuloma annulare is occasionally associated with diabetes or thyroid disease, most often when lesions are numerous or widespread. It may, rarely, be related to cancer, especially in older people whose granuloma annulare is severe, doesn't respond to treatment or returns after cancer treatment.
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Can granuloma annulare be misdiagnosed?

Granuloma annulare can be mistaken for other common annular skin conditions such as tinea corporis, pityriasis rosea, nummular eczema, psoriasis, or erythema migrans of Lyme disease. The lack of any surface changes to the skin is the key feature that distinguishes granuloma annulare from these other skin conditions.
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Granuloma annulare: treatments and causes: dermatologist Dr Dray



Should I be worried about granuloma annulare?

Because granuloma annulare usually causes no symptoms and clears up by itself, you may not need treatment (except for cosmetic reasons). It is not contagious. If you do receive treatment, it may include corticosteroids (cream, tape, or injections).
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What else looks like granuloma annulare?

Symptoms of the following disorder can resemble those of granuloma annulare. They may be useful for a differential diagnosis: Tinea corporis, also known as body ringworm, is a skin disorder characterized by an itchy skin rash. The arms and legs are the areas of the body most affected.
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What viral infections cause granuloma annulare?

Granuloma annulare has been hypothesized to be associated with tuberculosis, insect bites, trauma, sun exposure, thyroiditis, vaccinations, and viral infections, including HIV, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, and herpes zoster virus.
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Can parasites cause granuloma annulare?

Abstract. Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare.
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Can granuloma annulare be caused by stress?

Some reports associate chronic stress with granuloma annulare as a trigger of the disease. Granuloma annulare also has some predilection for the sun-exposed areas and photodamaged skin.
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Does lymphoma cause granuloma annulare?

Conclusion: Granuloma annulare with atypical clinical presentations may be associated with an underlying hematopoietic malignancy and may be part of a generalized granulomatous reaction to malignant lymphoma.
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What is Wiggins disease?

Overview. Chronic granulomatous (gran-u-LOM-uh-tus) disease (CGD) is an inherited disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn't work properly. As a result, the phagocytes can't protect your body from bacterial and fungal infections.
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What is interstitial granuloma annulare?

Granuloma annulare (GA) is a benign inflammatory skin disease of unknown origin, classically presenting with self-limited, skin-coloured to erythematous, papules with ring-shaped distribution with no epidermal changes, often located on the dorsal surfaces of the hands and feet.
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Is granuloma a cancer?

A granuloma is a small area of inflammation. Granulomas are often found incidentally on an X-ray or other imaging test done for a different reason. Typically, granulomas are noncancerous (benign). Granulomas frequently occur in the lungs, but can occur in other parts of the body and head as well.
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What is occult malignancy?

Occult primary tumors, or cancers of unknown primary (CUPs), are defined as histologically proven metastatic malignant tumors whose primary site cannot be identified during pretreatment evaluation. They have a wide variety of clinical presentations and a poor prognosis in most patients.
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Is malignancy always cancer?

If there are too many new cells, a group of cells, or tumor, can develop. Although some tumors are benign and consist of noncancerous cells, others are malignant. Malignant tumors are cancerous, and the cells can spread to other parts of the body.
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Does Vitamin E help granuloma annulare?

In our opinion, topically applied vitamin E for granuloma annulare allows fast and uncomplicated administration of drug to the lesion, it has a good therapeutic ratio without any adverse effects and can be used in children without precautions and thus, lastly, is cost-efficient.
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Is granuloma annulare related to diabetes?

Granuloma annulare (GA) is usually a self-limited, benign granulomatous disease of the dermis and subcutaneous tissue. It's generalized or disseminated form is associated with underlying diabetes mellitus and at times it precedes the sign and symptoms of diabetes mellitus.
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Is the sun good for granuloma annulare?

Light therapy: Exposing the skin with granuloma annulare to ultraviolet (UV) light in a controlled way can be helpful. Some people receive a type of light therapy called PUVA.
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Is granuloma annulare a connective tissue disease?

Actinic Granuloma An Annular Connective Tissue Disorder Affecting Sun and Heat-Damaged (Elastotic) Skin. Ring-shaped inflammatory lesions sometimes develop in the abnormal, "elastotic" connective tissues of skin damaged by sun and heat.
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How do you stop granuloma annulare from spreading?

Treatment options include:
  1. Corticosteroid creams or ointments. Prescription-strength products may help improve the appearance of the bumps and help them disappear faster. ...
  2. Corticosteroid injections. ...
  3. Freezing. ...
  4. Light therapy. ...
  5. Oral medications.
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Can viruses cause granulomas?

Other important causes of granulomas are parasitic infections (schistosomiasis, leishmaniasis, dirofilariasis, etc.) and rarely, viral infections caused by cytomegalovirus, Epstein-Barr virus and measles(Table 1-4).
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What are the side effects of granuloma?

Granulomas themselves don't usually have noticeable symptoms. But the conditions that cause them, such as sarcoidosis, tuberculosis, histoplasmosis, and others, may create symptoms.
...
Some of these include:
  • Shortness of breath.
  • Wheezing.
  • Chest pain.
  • Fever.
  • Dry cough that won't go away.
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What causes clusters of bumps on skin?

They can result from a number of conditions, including infections, allergic reactions, skin disorders, and skin cancer. Skin bumps can vary in appearance and number depending on the cause. They may be the same color as your skin or a different color.
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Can diet help granuloma annulare?

A diagnosis of generalized erythematous granuloma annulare was established based on the clinical and histopathological findings, especially with the distribution on more than one anatomic site. A lipid-lowering diet for three months resulted in major improvement of hyperlipidemia and remission of the skin lesions.
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