What can you not mix with Benadryl?

Benadryl may interact with other types of medication, which can heighten the side effects.
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Examples of medications that may interact with Benadryl include:
  • antidepressants.
  • stomach ulcer medicine.
  • cough and cold medicine.
  • other antihistamines.
  • diazepam (Valium)
  • sedatives.
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Does Benadryl interact with anything?

A total of 413 drugs are known to interact with Benadryl Allergy (diphenhydramine), categorized as 12 major, 399 moderate, and 2 minor interactions.
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Is Benadryl safe to take with other drugs?

Benadryl has the potential to interact with a variety of medications. It may interact with medications that are used to treat dementia and Alzheimer's disease, such as Aricept, Razadyne and Exelon. These medications and Benadryl can lessen the effects of each other.
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Can you drink soda with Benadryl?

Interactions between your drugs

No interactions were found between Benadryl and sodium bicarbonate. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Can you take Benadryl and Tylenol together?

Interactions between your drugs

No interactions were found between Benadryl and Tylenol. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Why doctors are advising against Benadryl



Can I take ibuprofen and Benadryl?

Interactions between your drugs

No interactions were found between Benadryl and ibuprofen. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Can I take an Advil with Benadryl?

Interactions between your drugs

No interactions were found between Advil and Benadryl. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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When should you not take Benadryl?

Benadryl shouldn't be used during the last two weeks of pregnancy. This is due to a risk of eye disease in the newborn. If you're pregnant, talk with your doctor before taking Benadryl.
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Does caffeine interact with Benadryl?

Interactions between your drugs

No interactions were found between Benadryl and caffeine. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Does milk interact with Benadryl?

Benadryl doesn't affect the amount of milk your body makes. However, it may decrease the flow of milk from your breasts. Benadryl can also be passed to your child through your breast milk when you take the pills or use it on your skin.
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Can Benadryl cause anxiety?

It's also possible that after taking Benadryl some people can feel: restless. excitable. anxious.
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Is it OK to take Benadryl every night?

Is it safe to take diphenhydramine every night? You should not take diphenhydramine every night. While it may be helpful during limited periods of insomnia, your body will build up a tolerance for the medication over time, and it will no longer have the desired effect.
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Is Benadryl good for sleep?

Although antihistamines like Benadryl will make you feel sleepy, they're not a great choice when it comes to treating insomnia. Not only can they affect your sleep quality, but they'll also become less effective very quickly, meaning you may not notice any benefits if you use them often.
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Is Benadryl good for anxiety?

Benadryl is not intended for long-term use, and while it may reduce anxiety symptoms in some individuals, the risks outweigh the benefits. Although it might provide temporary sleepiness, these effects don't last with regular use.
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How long does it take for the Benadryl to kick in?

How long does it take diphenhydramine (Benadryl) to start working? Diphenhydramine (Benadryl) starts to work pretty quickly. You can expect to it to kick in within about 15 to 30 minutes. Its full effects can be felt around 2 hours after your dose.
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How long does Benadryl make u sleep?

The effects of diphenhydramine last from four to six hours. Benadryl in the injectable form has a rapid onset of action. When used as a night-time sleeping aid, the usual dosage of Benadryl is 50mg at bedtime. A lower dosage may be needed in the elderly.
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How long does Benadryl last?

Benadryl is absorbed quickly in the body. You'll probably notice the effects within about 20 to 30 minutes. The medicine should continue to work for about four to six hours. You should only take Benadryl for a short amount of time, unless your doctor tells you to take it for longer.
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Does Benadryl make you sleepy?

First-generation antihistamines such as diphenhydramine (Benadryl®) usually cause drowsiness because they are less likely to affect the histamine produced in the brain or have other unwanted effects in the brain.
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Can Benadryl make your heart stop?

The U.S. Food and Drug Administration (FDA) is warning that taking higher than recommended doses of the common over-the-counter (OTC) allergy medicine diphenhydramine (Benadryl) can lead to serious heart problems, seizures, coma, or even death.
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How many Benadryl can I take to sleep?

How much Benadryl should I take to sleep? Typically two Benedryl tablets are taken to help with insomnia. Benadryl is commonly sold in 25 mg doses to treat an allergic reaction. For sleep, 50 mg of diphenhydramine is commonly recommended.
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Can I take Benadryl if I have Covid?

No. BENADRYL® products are only indicated to treat allergy symptoms, they are not symptomatic treatments for infectious diseases such as COVID-19.
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Can you take Claritin and Benadryl?

It's not recommended to take Claritin and Benadryl together. Because they have similar side effects, taking them together can increase the risk of adverse effects. Claritin has a relatively long half-life so it may not be safe to take Benadryl 12 hours after Claritin.
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How many Benadryl can I take?

Do not take more than 6 doses in 24 hours. Use only as directed. 2 to 4 chewable tablets (25 mg to 50 mg) every 4 to 6 hours or as directed by a doctor. 1 to 2 chewable tablets (12.5 mg to 25 mg) every 4 to 6 hours or as directed by a doctor.
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Is it OK to take Xanax and Benadryl together?

Alprazolam should not be taken with other benzodiazepine medications. Alprazolam may cause drowsiness, so caution should be used when combining it with other medications that cause drowsiness. These could include: Antihistamines such as diphenhydramine (Benadryl®)
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Can you take Benadryl with Tylenol and ibuprofen?

In general, it is safe to combine Benadryl with over-the-counter pain medicines such as ibuprofen or Tylenol.
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