What can mimic lupus symptoms?

Here are the conditions that are most likely to mimic the symptoms of lupus and how to make sure you get the right diagnosis.
  • Rheumatoid arthritis. ...
  • Rosacea and other skin rashes. ...
  • Dermatomyositis. ...
  • Undifferentiated Connective Tissue Disease. ...
  • Hashimoto's disease. ...
  • Sjögren's syndrome. ...
  • Fibromyalgia.
Takedown request   |   View complete answer on creakyjoints.org


What is lupus commonly misdiagnosed as?

Other skin conditions that sometimes mimic the skin problems of lupus include melasma, psoriasis, eczema (atopic dermatitis), and facial seborrheic dermatitis. A dermatologist can diagnose these skin conditions. The symptoms of clinical depression can mimic lupus symptoms, and vice versa.
Takedown request   |   View complete answer on healthgrades.com


What has similar symptoms to lupus?

Common diseases that overlap with lupus
  • Autoimmune thyroid disease.
  • Celiac disease.
  • Myasthenia gravis.
  • Antiphospholipid syndrome.
  • Rheumatoid arthritis.
  • Polymyositis.
  • Dermatomyositis.
  • Scleroderma.
Takedown request   |   View complete answer on lupus.org


Can you have lupus symptoms without having lupus?

Antinuclear antibody (ANA) test.

A positive test for the presence of these antibodies — produced by your immune system — indicates a stimulated immune system. While most people with lupus have a positive ANA test, most people with a positive ANA do not have lupus.
Takedown request   |   View complete answer on mayoclinic.org


Is lupus ever misdiagnosed?

A Lupus Foundation of America study of over 3,000 adults with lupus found that 46.5 percent report being misdiagnosed with something other than lupus at the start of their journey with this unpredictable and life-altering disease.
Takedown request   |   View complete answer on lupus.org


Lupus - Signs



How do you rule out lupus?

Your doctor will look for rashes and other signs that something is wrong. Blood and urine tests. The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus. Most people with lupus test positive for ANA.
Takedown request   |   View complete answer on cdc.gov


Can you still have lupus with normal blood work?

Dr. Michael Lockshin: The diagnosis of lupus is never made by blood test alone, since some people have positive blood tests but no disease. To make a diagnosis of lupus, you need to have both symptoms and, generally, positive blood tests.
Takedown request   |   View complete answer on hss.edu


Can ANA test be negative and you still have lupus?

Most people with lupus will have a positive ANA test result. It is very rare, but it is possible to have a negative ANA test and still have lupus. In these instances, other antibodies are present.
Takedown request   |   View complete answer on lupus.org


What are the top 5 signs of lupus?

  1. Fatigue. About 90 percent of people with lupus experience some level of fatigue. ...
  2. Unexplained fever. One of the early symptoms of lupus is a low-grade fever for no apparent reason. ...
  3. Hair loss. ...
  4. Skin rash or lesions. ...
  5. Pulmonary issues. ...
  6. Kidney inflammation. ...
  7. Painful, swollen joints. ...
  8. Gastrointestinal problems.
Takedown request   |   View complete answer on healthline.com


Do I have lupus checklist?

Common signs and symptoms of lupus

Extreme fatigue (feeling tired all the time) Pain or swelling in the joints. Swelling in the hands, feet, or around the eyes. Headaches.
Takedown request   |   View complete answer on lupus.org


Does a positive ANA always mean lupus?

If your doctor says your ANA test is “positive,” that means you have antinuclear antibodies in your blood — but it doesn't necessarily mean you have lupus. In fact, a large portion of patients with a positive ANA do not have lupus. Diagnosing lupus is like putting together a puzzle.
Takedown request   |   View complete answer on lupus.org


Can fibromyalgia be mistaken for lupus?

The common similarity between lupus and fibromyalgia is pain. In both diseases, pain can be exacerbated during flares of the condition. However, lupus symptoms show more visible distinctions. While both disorders can disrupt quality of life, lupus can pose more life-threatening complications.
Takedown request   |   View complete answer on healthline.com


What infections cause positive ANA?

In particular, several patients with a positive ANA test result were found to have intracellular infections such as mycobacterial infections, syphilis, or scrub typhus. Keywords: Antinuclear antibodies; autoimmune diseases; infection; scrub typhus; tuberculosis.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Is Sjogren's syndrome the same as lupus?

Sjogren's syndrome has a very slow, insidious onset. About 90% of individuals with Sjogren's symptoms are women, and the syndrome tends to aggregate to older individuals. Unlike lupus, Sjogren's afflicts all races equally.
Takedown request   |   View complete answer on hss.edu


What foods trigger lupus flare ups?

Alfalfa and garlic are two foods that probably shouldn't be on your dinner plate if you have lupus. Alfalfa sprouts contain an amino acid called L-canavanine. Garlic contains allicin, ajoene, and thiosulfinates, which can send your immune system into overdrive and flare up your lupus symptoms.
Takedown request   |   View complete answer on healthline.com


What is the first stage of lupus?

Lupus Symptom: Joint Pain

Joint and muscle pain is often the first sign of lupus. This pain tends to occur on both sides of the body at the same time, particularly in the joints of the wrists, hands, fingers, and knees. The joints may look inflamed and feel warm to the touch.
Takedown request   |   View complete answer on webmd.com


What triggers lupus flare ups?

Lupus flare-ups can be triggered by stress, infection, or missed doses of medication. To prevent a lupus flare, focus on your medication schedule, self-care, and sun protection. Hydroxychloroquine is the best medication to help prevent lupus flares.
Takedown request   |   View complete answer on goodrx.com


What cancers are associated with positive ANA?

Neoplastic diseases may cause positive ANA. Some authors have described that ANA is found in the sera from lung, breast, head and neck cancer patients as frequently as in RA and SLE 3, 4, 5. Chapman et al. 6 has suggested that in breast cancer they may be used as an aid to early diagnosis.
Takedown request   |   View complete answer on ncbi.nlm.nih.gov


How do rheumatologists diagnose lupus?

The rheumatologist will take a thorough history of your symptoms and do a physical exam looking for the signs and symptoms of lupus. They will also run blood tests to check for indications of lupus. The first blood test a rheumatologist will conduct to check for lupus is called an antinuclear antibody (ANA) test.
Takedown request   |   View complete answer on verywellhealth.com


Do all lupus patients have the butterfly rash?

About half of all lupus patients experience a characteristic rash called the malar or “butterfly” rash that may occur spontaneously or after exposure to the sun. This rash is so-named because it resembles a butterfly, spanning the width of the face and covering both cheeks and the bridge of the nose.
Takedown request   |   View complete answer on hopkinslupus.org


What is considered borderline lupus?

Borderline lupus, which can also be known as unspecified connective tissue disease, or probable lupus, or latent lupus, would define a patient who may have a positive ANA without a DNA or Smith antibody (blood tests used to diagnose lupus), who has arthralgias rather than arthritis, a brain fog or memory loss, and no ...
Takedown request   |   View complete answer on sharecare.com


Can you have lupus without the butterfly rash?

While the butterfly rash (also called a malar rash or lupus rash) is one of the most commonly known symptoms people associate with lupus, it does not need to be present to be diagnosed with lupus.
Takedown request   |   View complete answer on lupus.org


Does lupus cause weight gain?

Muscle pain — Muscle pain or tenderness is common in people with lupus; rarely, some people also notice muscle weakness. Weight changes — Lupus can sometimes cause weight loss or weight gain.
Takedown request   |   View complete answer on uptodate.com


What are the markers for lupus?

Antinuclear antibody (ANA) autoantibodies, or antibodies produced by the immune system that attack the body's own cells, are a hallmark of lupus. ANA is a screening test, since almost all patients with lupus have a strongly positive test.
Takedown request   |   View complete answer on hss.edu


Does lupus cause pain in legs?

Pain and aching in your muscles is common with lupus. You'll usually feel it in your thighs and upper arms. In about 5%-10% of people with lupus, the disease advances to myositis, which can cause painful muscle inflammation, especially in your shoulders, upper arms, hips, and thighs.
Takedown request   |   View complete answer on webmd.com
Previous question
How do you calculate family members?