What can cause a false high A1C?

A falsely high A1C result can occur in people who are very low in iron; for example, those with iron-deficiency anemia link. Other causes of false A1C results include kidney failure or liver disease.
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What can cause falsely elevated A1C?

Several medications and substances have also been reported to falsely elevate A1c including lead poisoning2, chronic ingestion of alcohol, salicylates, and opioids. Ingestion of vitamin C may increase A1c when measured by electrophoresis, but may decrease levels when measured by chromatography.
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Is it possible to have a high A1C and not be diabetic?

Yes, some conditions may raise the level of A1C in your blood, but that does not mean you have diabetes. According to a study by Elizabeth Selvin, a single elevated A1C level greater than 6% was found in the general population with no history of diabetes.
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Can A1C be misdiagnosed?

A widely used blood test to measure blood-sugar trends can give imprecise results, depending on a person's race and other factors. This test means diabetes can sometimes be misdiagnosed or managed poorly. Doctors have been cautioned before that results from the A1C test don't have pinpoint accuracy.
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What factors can affect the accuracy of your A1C test?

Several factors can falsely increase or decrease your A1C result, including:
  • Kidney failure, liver disease, or severe anemia.
  • A less common type of hemoglobin that people of African, Mediterranean, or Southeast Asian descent and people with certain blood disorders (such as sickle cell anemia or thalassemia) may have.
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Why Your A1c May Be INCORRECT! Your Doc May Not Even Know!



What can falsely lower A1C?

Conditions such as acute and chronic blood loss, hemolytic anemia, and splenomegaly can all cause falsely lowered A1c results. Patients with end-stage renal disease generally have falsely low A1c values. This is primarily due to the associated chronic anemia with decreased red cell survival” J Gen Intern Med.
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Why is my A1C normal but glucose is high?

A1C tests measure average blood glucose over the past two to three months. You may have high fasting blood sugar, but your overall blood sugar may be normal, or vice versa. Normal fasting blood sugar levels may not eliminate the possibility of type 2 diabetes.
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Is there a disease that mimics diabetes?

These include coeliac disease, thyroid disease and haemochromatosis.
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Can you be falsely diagnosed with diabetes?

Twenty-four percent of participants reported being misdiagnosed with another condition before being diagnosed with type 1 diabetes. The diagnosis was missed in 16% of those who were diagnosed at <18 years of age and in 38.6% of those who were diagnosed at ≥18 years of age (χ2[1] = 137.2, P <0.001).
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What is often mistaken for diabetes?

Type 1 diabetes is commonly confused with urinary tract infection, stomach flu, strep throat, or viral infections (like mononucleosis), as these conditions all have symptoms that overlap with diabetes.
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Can stress cause your A1C to be high?

Chronic stress—especially in relation to living with diabetes—was most strongly associated with A1c, particularly among subgroups that face disproportionate stress, such as minority groups or adolescents/young adults.
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Can low vitamin D cause high A1C?

The average A1c was higher in patients with severe vitamin D deficiency compared to those with normal levels of vitamin D. Those with severe deficiency had an average of 8.1%; those with normal vitamin D levels averaged 7.1%.
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Does dehydration affect A1C levels?

Quite simply, when you don't drink enough water, the glucose in your bloodstream becomes more concentrated. And that leads to higher blood sugar levels. Both mild and severe dehydration can have a notable impact on your diabetes.
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Does eating before A1C test affect results?

The A1C test is a simple blood test. You don't need to fast for the A1C test, so you can eat and drink normally before the test.
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What can cause a false diabetes diagnosis?

Other causes of false A1C results include kidney failure or liver disease. If you're of African, Mediterranean, or Southeast Asian descent or have family members with sickle cell anemia or a thalassemia link, an A1C test can be unreliable for diagnosing or monitoring diabetes and prediabetes.
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Can type 2 diabetes be mistaken for something else?

It's possible for someone with type 2 diabetes to be misdiagnosed. They may have many of the symptoms of type 2 diabetes, but actually have another condition that may be more closely related to type 1 diabetes. This condition is called latent autoimmune diabetes in adults (LADA).
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Can diabetes symptoms be something else?

Nausea and vomiting are other symptoms that could indicate diabetes, too. Both can occur as a result of neuropathy. Nerve damage may prevent your body from properly moving food from the stomach to the intestines.
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What is Pseudohypoglycemia?

Pseudohypoglycemia is an event when a person experiences typical symptoms of hypoglycemia but with a measured plasma glucose concentration above 70 mg/dL (>3.9 mmol/L). [1, 2] The term was used in the past to describe the disparity between actual and measured plasma/capillary glucose.
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What is Alstrom Syndrome?

Alström syndrome is characterized by a progressive loss of vision and hearing, a form of heart disease that enlarges and weakens the heart muscle (dilated cardiomyopathy ), obesity, type 2 diabetes (the most common form of diabetes), and short stature.
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What is Donohue syndrome?

Donohue syndrome is a rare disorder characterized by severe insulin resistance, a condition in which the body's tissues and organs do not respond properly to the hormone insulin.
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What is more accurate glucose or A1C?

Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a new study. HbA1c levels accurately predict future diabetes, and they better predict stroke, heart disease and all-cause mortality as well.
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Can A1C change in a month?

It's important to understand that lowering your A1C levels is a gradual (slow) process. As discussed, your A1C, unlike a blood glucose test, measures your average blood sugar over a period of 2 to 3 months. This means, it can take up to 3 months to notice significant changes in your A1C.
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At what A1C level does damage start?

Studies show a direct correlation between high A1C and severe diabetes complications. 3 An A1C level above 7% means someone is at an increased risk of complications from diabetes, which should prompt a person to make sure they have a plan in place to manage their blood sugar levels and decrease this risk.
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Why is A1C unreliable?

These disorders can affect reliability in three ways: 1) altering the normal process by which hemoglobin A is glycosylated to A1c, 2) making the red blood cells more prone to breakdown so there is less time for glycosylation, or 3) causing an abnormal peak in the chromatography so that the estimation of A1c is ...
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Does drinking lots of water help lower blood sugar?

Did you know it's Sugar Free February and that drinking water can help to lower blood sugar levels by diluting the amount of glucose (sugar) in your blood stream. By drinking water lots of water you can reduce your blood sugar as it indirectly will reduce insulin resistance and help reduce hunger.
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