What autoimmune disease is similar to MS?

Sjogren's syndrome is an autoimmune disease that can mimic some of the symptoms of MS such as fatigue and joint pain.
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What autoimmune diseases mimic MS?

These include fibromyalgia and vitamin B12 deficiency, muscular dystrophy (MD), amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), migraine, hypo-thyroidism, hypertension, Beçhets, Arnold-Chiari deformity, and mitochondrial disorders, although your neurologist can usually rule them out quite easily.
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What is the sister disease to MS?

Neuromyelitis optica spectrum disorder (NMOSD) shares some symptoms with multiple sclerosis and may be misdiagnosed as MS. It is also known as neuromyelitis optica (NMO) or Devic's disease. It's a rare autoimmune disorder of the central nervous system (CNS). The CNS consists of the optic nerves, brain and spinal cord.
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What can mimic multiple sclerosis?

There are also multiple infectious entities that mimic MS including; progressive multi-focal leukoencephalopathy (PML), Toxoplasmosis, Tuberculosis, Herpes Simplex Virus, Cytomegalovirus, Varicella zoster virus, Epstein Barr virus, Cryptococcus and Human immunodeficiency virus.
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What rare disease is similar to multiple sclerosis?

Devic's disease, also known as neuromyelitis optica (NMO) spectrum disorder, is a rare neuro-immune disorder that affects your eyes and your spinal cord. It may also attack the brain. Neuroimmune means that the immune system mistakenly attacks the nervous system as if it were a threat.
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Is Multiple Sclerosis Truly an Autoimmune Disease?



What mimics MS on MRI?

Hypoxic-ischemic vasculopathy, specially small-vessel disease, inflammatory disorders, vasculitis, and non-MS idiopathic inflammatory disorders, as well as some toxic, metabolic, and infectious disorders, may present mimicking MS on MR examinations and should be included in the differential diagnosis of MS-like lesions ...
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Could I have been misdiagnosed with MS?

Nearly one in five patients with an established diagnosis of multiple sclerosis (MS) are misdiagnosed, according to a 2019 study led by Cedars-Sinai. "Many physicians think diagnosing MS is simple," Marwa Kaisey, MD, one of the study's lead authors, said.
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How do you rule out multiple sclerosis?

Brain MRI is often used to help diagnose multiple sclerosis.
...
MRI multiple sclerosis lesions
  1. Blood tests, to help rule out other diseases with symptoms like MS . ...
  2. Spinal tap (lumbar puncture), in which a small sample of cerebrospinal fluid is removed from your spinal canal for laboratory analysis.
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What is the most common initial early symptom of multiple sclerosis?

Numbness or Tingling

Numbness of the face, body, or extremities (arms and legs) is often the first symptom experienced by those eventually diagnosed as having MS.
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What do you rule out before MS diagnosis?

While there is no definitive blood test for MS, blood tests can rule out other conditions that cause symptoms similar to those of MS, including Lyme disease, a group of diseases known as collagen-vascular diseases, certain rare hereditary disorders and acquired immune deficiency syndrome (AIDS).
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Can fibromyalgia be mistaken for MS?

But despite some similarities, “for the most part, there is no mistaking symptoms of MS with fibromyalgia,” says Philip Cohen, MD, a rheumatologist, professor of medicine and professor of microbiology and immunology at the Lewis Katz School of Medicine at Temple University in Philadelphia.
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Can vitamin B12 deficiency be misdiagnosed as MS?

A vitamin B12 deficiency can cause neurological symptoms that mimic those of multiple sclerosis (MS). Symptoms of both conditions include muscle weakness, difficulty walking, cognitive dysfunction, and sensory disturbances.
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What neurological disorder is like MS?

Neuromyelitis Optica Spectrum Disorder (NMOSD)

NMOSD is an inflammatory disease that, like multiple sclerosis, attacks the myelin sheaths — the protective covering of the nerve fibers — of the optic nerves and spinal cord, says Conway. But unlike MS, it usually spares the brain in its early stages.
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What autoimmune disorder attacks nerves?

Guillain-Barré syndrome (GBS) is a rare neurological disorder in which the body's immune system mistakenly attacks part of its peripheral nervous system—the network of nerves located outside of the brain and spinal cord.
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What autoimmune disease attacks muscles?

Myasthenia gravis (MG) is a chronic autoimmune disorder in which antibodies destroy the communication between nerves and muscle, resulting in weakness of the skeletal muscles. Myasthenia gravis affects the voluntary muscles of the body, especially those that control the eyes, mouth, throat and limbs.
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What part of the body does MS affect first?

Vision problems

In around 1 in 4 cases of MS, the first noticeable symptom is a problem with one of your eyes (optic neuritis). You may experience: some temporary loss of vision in the affected eye, usually lasting for days to weeks.
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Where does MS pain usually start?

These types of pain can happen anywhere on your body but are usually in the face, arms and legs. This type of nerve pain can present itself as: extreme sensitivity to touch. pins and needles.
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What are the facial symptoms of multiple sclerosis?

Usually, MS facial twitching affects one side of your face at a time. And you may notice other facial symptoms first, like numbness, tingling, weakness, or other weird sensations. “People will usually say, 'My face feels swollen, but I look in the mirror and it's not swollen,'” Stoll says.
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How can a neurologist tell if you have MS?

Neurological examination

Your neurologist will look for abnormalities, changes or weakness in your vision, eye movements, hand or leg strength, balance and co-ordination, speech and reflexes. These may show whether your nerves are damaged in a way that might suggest MS.
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When should you suspect multiple sclerosis?

Those symptoms include loss of vision in an eye, loss of power in an arm or leg or a rising sense of numbness in the legs. Other common symptoms associated with MS include spasms, fatigue, depression, incontinence issues, sexual dysfunction, and walking difficulties.
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How long can you have multiple sclerosis without knowing?

Canadian research shows people with MS are more likely than the general population to visit a doctor or hospital in the years leading up to an MS diagnosis.
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Can MRI rule out MS?

To detect MS.

MRI is considered the best test to help diagnose MS. However, 5% of people with MS do not have abnormalities detected on MRI; thus, a "negative" scan does not completely rule out MS. In addition, some common changes of aging may look like MS on a MRI.
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Does MS affect your nails?

Nail problems are common, and they are not usually serious. If a person has multiple sclerosis (MS), nail problems can cause pain or discomfort. While nail issues are not directly related to the disease, determining the cause may help prevent a person with MS from experiencing further discomfort.
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How accurate is MRI in diagnosing multiple sclerosis?

MRI plays a vital role in how we diagnose and monitor MS. In fact, over 90% of people have their MS diagnosis confirmed by MRI.
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