What are the worst side effects of Cymbalta?

Tell your doctor right away if any of these serious side effects occur: confusion, easy bruising/bleeding, decreased interest in sex, changes in sexual ability, muscle cramps/weakness, shaking (tremor), difficulty urinating, signs of liver problems (such as nausea that doesn't stop, stomach/abdominal pain, vomiting, ...
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What are the dangers of taking Cymbalta?

What Are Possible Side Effects Of Duloxetine? Headache, nausea, diarrhea, dry mouth, decreased appetite, increased sweating, feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia). These will often improve over the first week or two as you continue to take the medication.
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What drugs should not be taken with Cymbalta?

Drugs and substances that may interact with Cymbalta include:
  • MAO Inhibitors (Nardil, Parnate, others)
  • SSRIs (Celexa, Fluvoxamine, Lexapro, Prozac, Paxil, Symbyax, Zoloft)
  • Triptans (Amerge, Axert, Frova, Imitrex, Masalt, Replax, Zomig)
  • Other SNRIs (Pristiq, Fetzima, Ixel, Savella, Elamol, Tofacine, Effexor)
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Can Cymbalta make you crazy?

Like most antidepressants, Cymbalta (duloxetine) may trigger suicidal thoughts and behavior in children, adolescents and adults under the age of 24. As a result, patients should be closely monitored for changes in mood and behavior and the emergence of such symptoms.
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How long does it take for the side effects to go away from Cymbalta?

How long do Cymbalta (duloxetine) side effects last? The common side effects are nausea, headache, dry mouth, drowsiness, fatigue, constipation and difficulty sleeping. These side effects can go away within one to two weeks.
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What are the worst side effects of Cymbalta?



Has anyone had a good experience with Cymbalta?

Cymbalta has an average rating of 6.2 out of 10 from a total of 1,663 ratings on Drugs.com. 53% of reviewers reported a positive experience, while 30% reported a negative experience.
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How effective is Cymbalta for nerve pain?

Duloxetine at 60 mg daily is effective in treating painful diabetic peripheral neuropathy in the short-term to 12 weeks with a risk ratio (RR) for 50% pain reduction at 12 weeks of 1.65 (95% confidence interval (CI) 1.34 to 2.03), number needed to treat (NNT) 6 (95% CI 5 to 10).
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Does Cymbalta cause body odor?

Antidepressant medicines that can cause an increase in sweating include: Bupropion hydrochloride (Zyban) Clomipramine hydrochloride (Anafranil) Duloxetine hydrochloride (Cymbalta)
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Can Cymbalta cause anger?

Anger and Hostility Reported

Although Cymbalta is often used for anxiety, in some people it may have the opposite effect and cause tension and restlessness. Some people may find themselves more frustrated, irritable or lacking in patience when taking the drug.
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What are brain zaps from Cymbalta?

A study into Cymbalta, an antidepressant, found the most common withdrawal symptoms included electric-shock sensations in the brain (sometimes called "brain zaps"), dizziness, headache, nausea, and paresthesia.
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Does caffeine affect Cymbalta?

Interactions between your drugs

Caffeine may increase the blood levels and effects of DULoxetine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
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How fast does Cymbalta work for pain?

In clinical trials, Cymbalta significantly and quickly improved pain. More than half of the patients with fibromyalgia said they felt much better within one week. Pain relief may be greater in patients who also have existing depression, although those without depression also have a significant improvement in symptoms.
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Does Cymbalta give you energy?

Taking Cymbalta can improve mood, sleep, appetite and energy levels while also decreasing nervousness.
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What is Cymbalta mainly used for?

Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).
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Does Cymbalta affect blood pressure?

Duloxetine (Cymbalta). Used for the treatment of depression, anxiety, and chronic pain, Duloxetine raises systolic blood pressure by 2 to 4 points at approved doses. Higher doses of Duloxetine cause greater elevations in blood pressure and thus an increased risk of adverse cardiovascular events.
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Does Cymbalta make you gain weight?

Does Cymbalta Cause Weight Changes? Some people have reported weight changes, most notably weight gain, when taking antidepressant medications like Cymbalta. Overall, the research evidence for weight gain related to Cymbalta is mixed, but does not show big swings in weight in either direction.
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Does Cymbalta affect your eyesight?

But this drug may increase the risk of serious eye problems, such as glaucoma (a buildup of pressure within the eye). Cymbalta can cause a person's pupils to dilate. This can trigger a serious eye problem, including vision loss, especially for someone who has closed-angle glaucoma.
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How long does it take to adjust to Cymbalta?

by Drugs.com

It may take up to 6 to 8 weeks for the full effects of Cymbalta to be seen, although some improvement in symptoms, such as sleep, energy, or appetite may show an improvement in 1-2 weeks. Symptoms such as depressed mood and lack of interest in activities may take the full 6-8 weeks to resolve.
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What happens if you quit Cymbalta cold turkey?

Following abrupt or tapered discontinuation in placebo-controlled clinical trials, the following symptoms occurred at 1% or greater and at a significantly higher rate in duloxetine-treated patients compared to those discontinuing from placebo: dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, ...
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Why do I smell like onions?

Body odor is what you smell when your sweat comes in contact with the bacteria on your skin. Sweat itself doesn't smell, but when the bacteria on your skin mix with your sweat, it causes an odor. Body odor can smell sweet, sour, tangy or like onions. The amount you sweat doesn't necessarily impact your body odor.
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Why do I smell sickly sweet?

You May Have Diabetes, Or Liver Or Kidney Problems

"For example, people with diabetes have trouble breaking down glucose in the body, so you may notice that diabetics' breath often smells sweet because of a build-up of glucose."
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Does Cymbalta affect urination?

In conclusion, the risk that duloxetine will cause urinary retention seems limited. However, some patients may experience weak obstructive voiding symptoms most likely caused by peripheral adrenergic activity affecting the smooth urethral muscle or modifying the unique bladder-urethra synergy.
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Which is better for nerve pain gabapentin or Cymbalta?

The results showed that, at the end of the study, duloxetine was significantly superior to gabapentin in terms of the incidence of adverse reactions (RR = 0.59, 95% CI: 0.45–0.79, < 0.01), sleep interference score (SMD = −0.35, 95% CI: −0.63 to −0.08, < 0.05), but no significant differences in VAS score (SMD = −0.14, ...
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Does Cymbalta help with arthritis pain?

Clinical trials showed that taking Cymbalta significantly reduced chronic pain, compared with a placebo. More than 29,000 patients used Cymbalta in clinical trials, including people with osteoarthritis and chronic low back pain.
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Does Cymbalta help back pain?

A new study shows people with chronic low back pain treated with Cymbalta experienced a significantly greater improvement in average pain scores than those treated with a placebo.
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