What are the symptoms of high B12 levels?

What causes extremely high B12 levels?

Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)

Should I be worried if my B12 is high?

Though daily high doses of B12 are unlikely to cause harm in most people, extremely high doses should be avoided unless a healthcare professional prescribes it. If you think you may be deficient in B12, speak with your doctor, who can recommend an appropriate treatment based on your level of deficiency.

What cancers cause high B12?

In the Danish registry, a B12 > 800 pmol/L (1084 ng/L) was associated with the following cancer sites: pancreas, esophagus and stomach, colon and rectum, lungs, kidneys, urinary bladder, and strongly with liver [14].

Can too much B12 cause neuropathy?

Thus, vitamin B12 may be associated with both sensory and motor peripheral nerve function. In older adults, the prevalence of poor peripheral nerve function and neuropathy is high and increases with age^18–21.

What happens if your B12 is too high?

High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache. Nausea and vomiting. Diarrhea.

How do they treat high B12 levels?

If you're diagnosed with a B-12 deficiency, the goal of treatment is to increase your level of vitamin B-12. Your treatment may include: vitamin B-12 injection, with more frequent injections for those with severe deficiencies. daily vitamin B-12 supplements, such as Cyanocobalamin, which is a manmade vitamin B-12.

Why would B12 be high without supplements?

High or supraphysiological serum B12 levels without supplementation have been associated with many pathological conditions including renal failure, haematological disorders, cancer, and hepatic or autoimmune diseases. All conditions may show elevated concentrations of B12 transport proteins.

What can I do to lower my B12 level?

Research has suggested that the consumption of alcohol may reduce vitamin B12 levels. An older study indicated that moderate alcohol intake diminished vitamin B12 by 5% among “healthy, well-nourished, postmenopausal women.” Alcohol-related liver disease may falsely increase vitamin B12 test levels.

Can stress cause high B12 levels?

Those who have to deal with highly stressful situations or are in a serious crisis need more vitamin B12 than usual. These situations can be high mental or physical stress such as important exams or difficult tests.

Is B12 level of 1500 too high?

There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.2¹⁹; 513¹; 700 (high) and 1500 (very high)¹¹; and 601 (high) and 1000 (very high)¹⁰.

Can too much vitamin B hurt you?

Consuming vitamin B-6 through food appears to be safe, even in excessive amounts. When used as a supplement in appropriate doses, vitamin B-6 is likely safe. However, taking too much vitamin B-6 from supplements can cause: A lack of muscle control or coordination of voluntary movements (ataxia)

How long does it take for B12 to decrease?

Unlike most other vitamins, B12 is stored in substantial amounts, mainly in the liver, until it is needed by the body. If a person stops consuming the vitamin, the body's stores of this vitamin usually take about 3 to 5 years to exhaust.

What medications should not be taken with B12?

Certain medications can decrease the absorption of vitamin B12, including: colchicine, metformin, extended-release potassium products, antibiotics (such as gentamicin, neomycin, tobramycin), anti-seizure medications (such as phenobarbital, phenytoin, primidone), medications to treat heartburn (such as H2 blockers ...

Can vitamin B12 cause heart problems?

Macrocytosis associated with vitamin B12 deficiency is also associated with fatal and non-fatal coronary disease, myocardial infarction, stroke, and other circulatory health problems.

Can B12 cause anxiety?

B12 deficiencies are often a root cause of neurological, psychiatric and cognitive issues. Having a B12 deficiency puts you at risk for developing depression and anxiety, fatigue, and can worsen hypothyroid and other health concerns.

Can autoimmune cause high B12?

Abnormally elevated B12 has been attributed many causes [5,6], e.g., myeloid blood malignancies [7,8,9], acute or chronic liver diseases [10,11,12], chronic kidney failure, autoimmune or inflammatory diseases [3], and Gaucher disease [13].

Can too much B12 cause panic attacks?

Some of the negative side effects of vitamin B overdose include mood swings, restlessness, depression, and panic attacks. Mood swings can worsen in people who suffer from paranoia, confusion, or mental fogginess; due to the high doses of vitamin B complex.

Can high B12 cause insomnia?

At the same time, the influence of B12 directly on sleep isn't clear. Some studies show a connection between low vitamin B12 and insomnia, while other studies show higher levels of vitamin B12 are linked to sleep disruption and shorter sleep times.

Can B12 cause weight gain?

Despite the numerous processes in which vitamin B12 is involved, there's little evidence to suggest that it has any influence on weight gain or loss.

Can high B12 cause liver problems?

It has been previously reported that highly elevated vitamin B₁₂ levels in plasma were indicated in acute hepatitis, severe alcoholic liver disease, and cirrhosis. Our data indicate that serum vitamin B₁₂ levels were falsely elevated with the severity also in chronic viral liver disease.

Does B12 affect cholesterol?

They found that low levels of vitamin B12 were associated with higher levels of total cholesterol, LDL (bad) cholesterol, and triglycerides—even after adjusting for the effects that body mass index, abdominal fat, and total body fat percentage have on the body.

Can B12 cause palpitations?

Symptoms of Vitamin B12 Deficiency

A mild deficiency may cause no symptoms. But if untreated, it may lead to symptoms such as: Weakness, tiredness, or lightheadedness. Heart palpitations and shortness of breath.

What is normal level of vitamin B12 in elderly?

A serum vitamin B₁₂ level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly.

How much vitamin B12 should a senior take?

Dosages for Older People

Around this age, you should be getting around 2.4 micrograms of B12 a day. Not only does this mean consciously eating foods that contain vitamin B12 but it also means that you should ingest this vitamin as a supplement. By taking supplements, you will ensure that your body absorbs vitamin B12.