What are the side effects of lithium?

What are the long term side effects of taking lithium?

The most concerning side effects of long term lithium use are hypothyroidism and kidney problems. According to a 2015 review article , these side effects are most likely to affect women below the age of 60 years. They are also more common among people with higher-than-average concentrations of lithium in the blood.

What does lithium do to a person?

Lithium acts on a person's central nervous system (brain and spinal cord). Doctors don't know exactly how lithium works to stabilize a person's mood, but it is thought to help strengthen nerve cell connections in brain regions that are involved in regulating mood, thinking and behavior.

What are the 3 main symptoms of lithium toxicity?

Some signs of lithium toxicity are similar to its side effects, but more severe. Symptoms of lithium toxicity include severe nausea and vomiting, severe hand tremors, confusion, and vision changes. If you experience these, you should seek immediate medical attention to check your lithium levels.

What should you avoid when taking lithium?

NSAIDs (Nonsteroidal anti-inflammatory drugs) interacts with LITHIUM. NSAIDs might increase lithium levels in the body. Taking lithium along with NSAIDs might increase the risk of lithium side effects. Avoid taking lithium supplements and NSAIDs at the same time.

Lithium: Adverse Effects and Interactions – Pharmacology | Lecturio Nursing

What does it feel like to be on lithium?

The most common side effects of lithium are feeling or being sick, diarrhoea, a dry mouth and a metallic taste in the mouth. Your doctor will carry out regular blood tests to check how much lithium is in your blood.

Is lithium good for anxiety?

Lithium improves the body's ability to synthesize serotonin. This simply means that the body's levels of serotonin increase in response to lithium, which has the effect of improving mood and reducing feelings of anxiousness.

Is 600 mg of lithium a lot?

Adults and children 12 years of age—600 milligrams (mg) 2 times a day, or 3 times a day up to 1200 mg per day. Children younger than 12 years of age—Use is not recommended.

What should I watch when taking lithium?

Dizziness, blurred vision, ringing in the ears and excessive production of dilute urine may occur with higher (toxic) lithium levels. Seek urgent medical advice. Lithium may also cause irregular heartbeat, drying and thinning of hair, alopecia, dry mouth, weight gain, itchiness, and other side effects.

How common is weight gain on lithium?

Approximately 25% of people gain weight from taking lithium, according to a review article published in Acta Psychiatrica Scandinavica. 1 After analyzing all relevant published medical studies, the authors reported an average weight gain of 10 to 26 pounds among those who experience this troubling side effect.

Is lithium used for sleep and anxiety?

With low-dose lithium supplementation, patients typically report fewer mood swings, less anxiety, and better sleep. After magnesium, lithium seems to have the most benefits and receives the most positive feedback of the supplements that I recommend.

Does lithium shorten your lifespan?

Lithium treatment in the range of 1 to 25 mM resulted in lifespan extension, whereas higher doses (50–100 mM) shortened lifespan (Figure 1A). These effects of lithium treatment on lifespan extension were also observed in an independent genetic background (Figure S1A) and in males (Figure S1B).

Is lithium used for sleep?

In addition to its predominant use for the prophylaxis of recurrent mania and depression, lithium carbonate has been proposed and tried in the prophylactic treatment of abnormally prolonged sleep episodes featuring the Kleine-Levin syndrome.

Why is lithium being discontinued?

Results. Of 873 patients treated with lithium, 54% discontinued lithium, corresponding to 561 episodes of lithium discontinuation. In 62% of episodes, lithium was discontinued due to adverse effects, in 44% due to psychiatric reasons, and in 12% due to physical reasons interfering with lithium treatment.

What is the life expectancy of a person with bipolar disorder?

The authors found that the pooled life expectancy for patients with bipolar disorder, after removal of 1 outlier study, was 67.4 years (95% CI 65.2-69.7), with no evidence of publication bias. Life expectancy was significantly shorter in men (64.6) compared to women (70.5).

How long do you take lithium for?

Patients continuing taking lithium should take a reduced dosage or even stop taking lithium in the critical period of heart development (4 to 12 weeks). However, lithium should never be discontinued abruptly.

How can I avoid gaining weight on lithium?

Weight gain is a known unwanted side effect associated with lithium use. Limiting caloric intake from beverages can help avoid or keep weight gain to a minimum. Lithium can make you very thirsty. Replace sugary drinks or juices with water, flavored waters, or other low- to no-calorie beverages.

How often do lithium levels need to be checked?

Regular blood tests are necessary to check lithium levels and to make sure you are taking the right dose. They will be checked weekly or fortnightly at first. Once levels of lithium in the blood are steady, they will be checked regularly (typically 3 monthly), usually 12 hours after the last dose.

Is it hard to get off of lithium?

If you need to stop taking lithium, it is best for you to come off it gradually, over at least four weeks, but preferably over three to six months. Gradually reducing the dose will make it less likely that your symptoms come back (compared to stopping the lithium quickly).

Is it better to take lithium in the morning or at night?

Take your lithium each night at the same time. You need to take it at night because blood tests need to be done during the day, 12 hours after a dose (see Section 4 'Blood tests after starting to take lithium').

What painkillers can I take with lithium?

If you do need a pain reliever while taking lithium, acetaminophen (Tylenol®) is a safe alternative. Sulindac (Clinoril®), a prescription pain reliever, can also be used as an alternative. Also, too much caffeine can decrease the effectiveness of lithium and possibly increase your symptoms.

Can lithium make you worse?

There are cases when suicidal thoughts or bipolar tendencies become temporarily, or permanently, worse when you start taking lithium. If you feel that your symptoms are worsening, call the doctor who prescribed lithium to you and discuss your options.

Is lithium worth taking?

The special usefulness of lithium lies in long-term prevention of recurrences of mania and bipolar depression and in reducing risk of suicidal behavior. Lithium also may be beneficial in recurrent unipolar depression and is an effective adjunct for treatment-resistant depression.

Is 300mg of lithium a lot?

The right dosage of lithium varies from person to person, but most people are prescribed between 900 milligrams (mg) to 1,200 mg per day, in divided doses. Some people take more than 1,200 mg per day, especially during acute episodes. Others may be more sensitive to lower doses.