What are the long term side effects of radioactive iodine?

Possible long term side effects include:
  • Ability to have children (fertility) Some women may have irregular periods after radioactive iodine treatment. ...
  • Inflammation of the salivary glands (where spit is made) ...
  • Tiredness. ...
  • Dry or watery eyes. ...
  • Lower levels of blood cells. ...
  • Lung problems. ...
  • Second cancers.
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Are there long term effects of radioactive iodine treatment?

NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism. New study findings show an association between the dose of a common treatment for hyperthyroidism and risk of death from solid cancers.
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Does radioactive iodine shorten life?

Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery.
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What are the risks of radioactive iodine treatment?

People who have had RAI therapy may have a slightly increased risk of developing leukemia, stomach cancer, and salivary gland cancer in the future.
...
Short-term side effects of RAI treatment may include:
  • Neck tenderness and swelling.
  • Nausea and vomiting.
  • Swelling and tenderness of the salivary glands.
  • Dry mouth.
  • Taste changes.
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Can radioactive iodine cause other cancers?

Patients treated with radioactive iodine also have an increased risk of acute lymphocytic leukemia (ALL), stomach cancer, and salivary gland cancer.
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The risks of radioactive iodine treatment in thyroid cancer



Can thyroid grow back after radioactive iodine treatment?

Once hypothyroidism has been achieved, it is usually irreversible with the patient requiring lifelong thyroid replacement. Early recurrences are reported in 20–54% of cases within 3–6 months, which can be due to inadequate RAI treatment or early Marine Lenhart syndrome.
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Does thyroid removal shorten life expectancy?

We have also shown that treatment per se (thyroidectomy, high-dose radioactive iodine and thyroid hormone medication) is safe and does not shorten life expectancy.
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Will I gain weight after radioactive iodine treatment?

Treatment of hyperthyroidism with RAI or anti-thyroid medications is associated with an increased risk of gaining weight and even developing obesity. This risk is slightly higher with RAI therapy compared to medications.
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Is there an alternative to radioactive iodine?

These alternative therapies include two major categories: redifferentiation therapy and recent molecular target therapy. Several clinical trials have investigated these therapies. They demonstrated potential effects of the therapies, although the results have been somewhat limited so far.
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Is radioactive iodine serious?

Radioactive iodine (RAI) is treatment for overactive thyroid (hyperthyroidism) and certain types of thyroid cancer. The term “radioactive” may sound frightening, but it is a safe, generally well-tolerated, and reliable treatment that targets thyroid cells so there is little exposure to the rest of your body's cells.
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Does radioactive iodine affect teeth?

High-dose radioiodine treatment can impair the long-term dental health, depending on the intensity of treatment and individual radioiodine uptake within the salivary glands. Patients should be made aware of salivary gland damage before high-dose radioiodine treatment.
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Can radioactive iodine cause kidney problems?

The renal cast formation and tubular damage are evaluated by a pathologist in a blinded manner. Results: Ablative radioiodine-131 therapy induced renal tubular damage was significantly higher in the radioactive iodine fifth day group (RI-5) when compared with the Sham group (p=0.01) and Amifostine group (p=0.01).
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How many times can you have radioactive iodine treatment?

You may only need to have this treatment once. But it can be repeated every 3 months if needed, until there is no sign of any thyroid cancer on your scans.
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How long do side effects from radioactive iodine last?

You may have short term changes to your taste and smell. This may not start until you get home. It usually gets better within 4 to 8 weeks. It can help to drink plenty of fluids after your treatment.
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What happens to your thyroid after radioactive iodine?

Radioactive iodine is taken up by the thyroid, and destroys the cells in the thyroid gland. This has the effect of reducing the amount of thyroxine made by the thyroid gland and may also reduce the size of the gland.
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Which is better thyroid surgery or radioactive iodine?

Surgery for hyperthyroidism was associated with a lower risk of all-cause and cardiovascular death as compared to radioactive iodine therapy during long-term follow-up, particularly in men.
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Can you refuse radioactive iodine treatment?

When patients refuse RAI therapy, the harm associated with no treatment (as in thyroid cancer) also must be weighed and communicated to the patients. In many cases of GD, for example, the use of antithyroid medications or surgical subtotal thyroidectomy may provide appropriate therapy without the use of RAI.
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Can you drink alcohol after radioactive iodine?

Continue the low iodine diet for 3 days. Avoid alcoholic beverages for 3 days.
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What happens if radioactive iodine does not work?

Thyroid cancer that no longer responds to radioactive iodine may become sensitive after starting anti-cancer drugs.
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What are the symptoms if your thyroid medication is too high?

Symptoms of severe overtreatment include:
  • Anxiety.
  • Mood swings.
  • Hand tremors.
  • Diarrhea.
  • Muscle weakness, mainly in the thighs and shoulders.
  • Weight loss.
  • Inability to sleep and/or focus.
  • Abnormally increased heart rate, even at rest.
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How do you wash clothes after radioactive iodine treatment?

Personal clothing, sheets, bedding, washcloths, and towels should be collected and washed separately for the first 48 hours. After washing, run the washing machine through an extra wash cycle to clear out any residual radioiodine before using it for others.
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How can I not gain weight after thyroidectomy?

Upping your fiber intake: Getting a good amount of fiber is one of the basic tactics you can employ as a thyroid patient if you want to lose weight. It can come from high-fiber foods, supplements, or both. Limiting simple carbohydrates and sugar: Try following a low-glycemic diet to avoid high blood sugar.
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Can you survive without a thyroid and no medication?

Aside from having your thyroid levels tested regularly and taking medication daily to give your body the thyroid hormone it needs, people without a thyroid live an otherwise normal life. Adjusting to life without your thyroid means taking medication and checking in with your doctor. Most people adjust easily.
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How many years can a thyroid patient live?

Conclusions and Relevance At the age of 50 years, participants with low-normal thyroid function live up to 3.5 years longer overall and up to 3.1 years longer without CVD than participants with high-normal thyroid function.
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Can a removed thyroid grow back?

A recurrent goiter is the regrowth of thyroid tissues after thyroidectomy. This may occur after surgery for benign disease or malignancy of thyroid. While recurrence after surgery for benign disease should be preventable, recurrence after malignant disease depends on many factors.
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