What are the long term side effects of cabergoline?

Cabergoline can cause heart and lung problems, particularly in people who need to take it over a long period of time. In order for your doctor to check for this, you may need to have an ECG, lung function tests, blood tests and an X-ray from time to time if you are taking cabergoline long-term.

What does cabergoline do to the brain?

It works by stopping the brain from making and releasing the prolactin hormone from the pituitary gland. Cabergoline use is usually stopped when prolactin levels are normal for 6 months. It may be given again if symptoms of too much prolactin occur again. This medicine is available only with your doctor's prescription.

Do you have to take cabergoline for life?

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Can cabergoline cause liver damage?

Cabergoline has been reported to cause liver failure, which can cause death. This medication may also cause a decrease in liver function.

What is the side effect of cabergoline?

Nausea, vomiting, stomach upset, constipation, dizziness, lightheadedness, or tiredness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What are the side effects of Cabergoline?

Can cabergoline cause heart problems?

Cabergoline, a dopamine receptor-2 agonist used to treat prolactinomas and Parkinson's disease, is associated with increased risk of cardiac valve disease due to increased frequencies of valvular thickening, calcifications,fibrosis and increased mitral tenting area.

Does cabergoline shrink pituitary tumors?

Cabergoline (CAB) is a dopamine agonist widely used clinically for the treatment of pituitary adenomas and Parkinson disease (1, 2). It is the first choice for the treatment of prolactinomas because it effectively reduces prolactin (PRL) secretion and shrinks tumors in most patients (2, 3).

Can you take cabergoline long term?

Cabergoline can cause heart and lung problems, particularly in people who need to take it over a long period of time. In order for your doctor to check for this, you may need to have an ECG, lung function tests, blood tests and an X-ray from time to time if you are taking cabergoline long-term.

How long can I take cabergoline?

Use the medicine exactly as directed. Cabergoline is usually taken twice each week for at least 6 months. Do not take this medicine every day unless your doctor tells you to.

Does cabergoline make you happy?

In the first two weeks, I noticed a boost in my mood and energy levels. It was as if a fog of depression had been lifted from me. I had mild headaches and a slight loss of appetite. Longer-term, the headaches and nausea subsided and my mood leveled out.

What happens when you stop cabergoline?

Although not specifically reported in this meta-analysis, a further reassuring factor that should convince clinicians to make at least one attempt to stop cabergoline is that, when withdrawal is not successful, serum prolactin increase occurs before any visible increase in tumor size by MRI [6, 12].

Can cabergoline cure prolactinoma?

Treatment of invasive giant prolactinoma using cabergoline has been observed to provide excellent outcomes in treating an extensive prolactinoma with locoregional spread and visual field compromise, starting with 0.25 mg/week and increased to 1 mg/week, with serum prolactin decreasing to 192 ng/mL at 8 months from an ...

What happens if you take too much cabergoline?

What happens if I overdose on Cabergoline (Dostinex)? Overdose symptoms may include stuffy nose, hallucinations, or fainting.

Can cabergoline affect memory?

We found a significant improvement in the speed of processing, working memory, visual learning and reasoning and problem-solving domains after cabergoline treatment. Improvements in speed of processing and reasoning and problem solving were greater in patients with baseline prolactin levels above the median.

What are the benefits of cabergoline?

What is the benefit of taking cabergoline? The benefit of taking cabergoline is that it can reduce the level of prolactin in your blood and reduce the symptoms you have been experi- encing. It works by increasing a chemical in the brain called dopamine, which reduces the amount of prolactin that is produced.

Can cabergoline cause mood swings?

While generally well tolerated, these agents can cause psychiatric adverse side effects including depression, somnolence, anorexia, anxiety, insomnia, impaired concentration, nervousness, hallucinations, nightmares, psychosis, and mania.

What is the best drug for high prolactin?

Cabergoline – Cabergoline is taken once or twice a week and is much less likely to cause nausea compared with other dopamine agonists. It may be effective for treating prolactinomas that are resistant to bromocriptine. For all these reasons, cabergoline is the best first choice.

How long does it take for cabergoline to lower prolactin levels?

Cabergoline induced a marked fall in serum PRL which began within 3 h and continued for 7 days. The maximal decrease ranged between -49.2% and -55.2% and occurred after 2-5 days. This maximal effect was only slightly less than that 6 h after bromocriptine treatment (-63.8%).

Does cabergoline make you gain weight?

Conclusion: Cabergoline is unlikely to be considered as a useful weight loss agent, but in this study it was associated with weight stability compared to the weight gain that occurred amongst individuals who did not start dopamine agonist treatment.

How fast does cabergoline shrink tumor?

Tumor shrinkage was significant (86% reduction) within 6 months although a further decrease (97%) in tumor size was observed after >12 months of cabergoline treatment.

Does cabergoline reduce estrogen?

Intermittent administration of cabergoline (0.6 mg/kg p.o. every 3 days), starting from the first day of estrogen treatment, completely counteracted the development of the prolactinoma, as judged by the weight of the pituitary and the stimulating effect of estrogens on plasma prolactin and mitotic rate and DNA ...

Can you live a normal life with a pituitary tumor?

In general, when a pituitary tumor is not cured, people live out their lives but may have to deal with problems caused by the tumor or its treatment, such as vision problems or hormone levels that are too high or too low.

What is the survival rate for pituitary tumor?

The 5-year survival rate tells you what percent of people live at least 5 years after the tumor is found. Percent means how many out of 100. The 5-year survival rate for people with a pituitary gland tumor is 97%. Survival rates depend on the type of tumor, the person's age, and other factors.

Can pituitary tumors be cured?

Most pituitary tumors are curable. If a pituitary tumor is diagnosed early, the outlook for recovery is usually excellent. However, if tumors grow large enough, or grow rapidly, they are more likely to cause problems and will be more difficult to treat.