What are the long-term side effects of antidepressants?

Can antidepressants cause long-term damage?

Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.

Can antidepressants permanently change your brain?

Some research has suggested this type of drug aids in neuroplasticity. In other words, these drugs can affect how our minds organize and form synaptic connections. Other researchers believe this type of medication has no long-term effects on our brains once the individual stops using the drug.

How long is too long to be on antidepressants?

It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.

Do antidepressants affect life expectancy?

The analysis found that in the general population, those taking antidepressants had a 33 percent higher risk of dying prematurely than people who were not taking the drugs. Additionally, antidepressant users were 14 percent more likely to have an adverse cardiovascular event, such as a stroke or a heart attack.

The 'extreme' side-effects of antidepressants - BBC News

Is it okay to be on antidepressants for years?

Long-term—even indefinite—use of antidepressants may be the best treatment for someone with multiple past episodes of depression, especially if they have a history of suicide attempts or have residual symptoms, like sleep problems, says Dr. Potash.

Do antidepressants damage your brain?

We know that antipsychotics shrink the brain in a dose-dependent manner (4) and benzodiazepines, antidepressants and ADHD drugs also seem to cause permanent brain damage (5).

What are the benefits of coming off antidepressants?

Besides easing the transition, tapering the dose decreases the risk that depression will recur. In a Harvard Medical School study, nearly 400 patients (two-thirds of them women) were followed for more than a year after they stopped taking antidepressants prescribed for mood and anxiety disorders.

Do antidepressants cause dementia?

Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer's Society and published today in the British Medical Journal.

Is there an alternative to antidepressants?

Exercise. Research suggests that regular exercise may be a more effective treatment for mild depression than antidepressants. Exercise helps boost levels of chemicals called serotonin and dopamine in the brain, which can lift your mood.

Do antidepressants affect intelligence?

Serretti et al. showed that using SSRIs even in healthy individuals leads to cognitive impairment [25]. The memory loss caused by SSRIs has not yet been convincingly explained; however, serotonin appears to play an important role in learning and memory [26].

Do antidepressants affect memory?

Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.

What happens to your brain when you stop taking antidepressants?

Quitting an antidepressant suddenly may cause symptoms within a day or two, such as: Anxiety. Insomnia or vivid dreams. Headaches.

Do antidepressants heal the brain?

Scientists have long known that SSRIs rapidly increase the available amount of the neurotransmitter serotonin, leading to changes that go well beyond brain chemistry: Research suggests the drugs help reverse the neurological damage associated with depression by boosting the brain's innate ability to repair and remodel ...

What is the truth about antidepressants?

In general, antidepressants work really well, especially when used along with psychotherapy. This combination may give you better results than using either treatment alone. Most people on antidepressants say they have eventual improvements in symptoms such as sadness, loss of interest, and hopelessness.

Are antidepressants harmful?

Antidepressants can cause dizziness and unsteadiness, increasing the risk of falls and bone fractures, especially in older people. Interactions with other medications can increase this risk. A very small number of people have had heart problems, epileptic fits or liver damage while taking antidepressants.

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Does brain fog from antidepressants go away?

These symptoms of brain fog may be short-term or ongoing as you take these medications. While antidepressants are generally intended to help with brain fog, some can cause brain fog as a side effect, depending on the medication and your unique response to it.

What is Sundowning behavior?

Late afternoon and early evening can be difficult for some people with Alzheimer's disease. They may experience sundowning—restlessness, agitation, irritability, or confusion that can begin or worsen as daylight begins to fade—often just when tired caregivers need a break.

How do you know when to come off antidepressants?

The longer you have taken your medication, the slower you might want to cut down. Current recommendations for reducing the dose of an antidepressant are: If treatment has lasted less than eight weeks, stop over 1-2 weeks. If a treatment has lasted 6-8 months, cut down over 6-8 weeks.

Can antidepressants make you mean or angry?

SSRIs are the first line of therapy for anxiety and depressive disorders and for many other clinical diagnoses. One of the most disturbing side effects that is observed is a tendency towards aggressiveness among patients receiving medications from this group, mainly during the first month of therapy.

What happens if you stop antidepressants cold turkey?

Abruptly discontinuing antidepressants can lead to rebound depression, or symptoms returning even stronger than before. Rebound depression is a symptom of withdrawal and eventually fades away. Not everyone experiences rebound depression.

Do antidepressants shrink brain?

Depression changes the brain. Imaging studies have reported thinning of the cortex, while structures such as the hippocampus show a loss of gray matter possibly associated with the loss of neurons and fewer neuronal connections.

Can antidepressants cause Parkinson's?

Our study shows that the risk of PD increases during the first two years of use of antidepressants, whether they are tricyclic antidepressants or SSRIs. The increased PD risk that follows initiation of antidepressants was greater among individuals with recent history of depression than among the others.

How do you know if your antidepressant is too high?