What are the long-term effects of taking omeprazole for years?

Long-term side effects
Taking omeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
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Can you take omeprazole for 20 years?

You shouldn't take OTC omeprazole for longer than 14 days without a healthcare provider's OK. Prescription omeprazole is often taken for 4 to 8 weeks, depending on what you're treating. For some conditions, it's taken for even longer. Taking omeprazole for too long can lead to serious side effects.
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What is the longest you should take omeprazole?

If you bought the medicine yourself from a pharmacy or supermarket, you can take it for up to 14 days. If you feel no better after taking omeprazole for 14 days, tell your doctor. They may want to do tests to find out what's causing your symptoms or change you to a different medicine.
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What can I take instead of omeprazole long term?

  • Famotidine.
  • Protonix.
  • Prilosec.
  • Dexilant.
  • Prilosec OTC.
  • Aciphex.
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Can long term use of omeprazole cause stomach problems?

Taking omeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk. If you use omeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency.
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How and When to take Omeprazole (Prilosec / Losec) | Side Effects All Patients Need to Know



What are symptoms of too much omeprazole?

Serious stomach conditions may occur while taking this medicine alone or together with antibiotics. Check with your doctor immediately if you or your child has stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness.
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What are the most severe adverse effect of omeprazole?

Omeprazole may help your stomach symptoms related to acid, but you could still have serious stomach problems. This medication may increase your risk of severe diarrhea. This diarrhea may be caused by an infection (Clostridium difficile) in your intestines.
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How do I get off omeprazole naturally?

Slowly taper off the PPI over 2-4 weeks (the higher the dose, the longer the taper). While the taper is being completed, use the following for bridge therapy to reduce the symptoms of rebound hyperacidity. Encourage regular aerobic exercise. Encourage a relaxation technique such as deep breathing.
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Is there a better drug than omeprazole?

Another analysis of several studies found that esomeprazole 40 mg was more effective than omeprazole at treating esophagitis (inflammation of the esophagus) due to GERD after 8 weeks of treatment.
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What is the safest antacid for long term use?

Results of numerous clinical trials indicate that oral pantoprazole is safe and well tolerated for short-term treatment of GERD and for longer term maintenance therapy in patients with healed erosive esophagitis.
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What can you take everyday for acid reflux?

Proton pump inhibitors (PPIs)
  • Prevacid 24HR (lansoprazole)
  • Nexium 24HR (esomeprazole)
  • Prilosec OTC (omeprazole magnesium)
  • Zegerid OTC (omeprazole and sodium bicarbonate)
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What does omeprazole do to your body?

Omeprazole reduces the amount of acid your stomach makes. It's widely used to treat indigestion and heartburn, and acid reflux. It's also taken to prevent and treat stomach ulcers. Omeprazole is a type of medicine called a proton pump inhibitor (PPI).
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Who should not take omeprazole?

Do not use omeprazole if you are also using medicines containing rilpivirine (Edurant®, Complera®). Using these medicines together may cause unwanted side effects. This medicine is sometimes given together with other medicines to treat ulcers.
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Why do I have to take omeprazole for life?

Keep in mind that omeprazole is only intended for short-term treatment of heartburn, GERD, and other gastrointestinal conditions. Long-term use is only advised for people with rare medical conditions that cause hypersecretion of stomach acid.
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Is it hard to stop taking omeprazole?

A. Stopping powerful acid-suppressing drugs like omeprazole (Prilosec), esomeprazole (Nexium) or lansoprazole (Prevacid) can be tough. (We have written about this problem before.) In one study, even people who had never had heartburn before developed it when they abruptly stopped taking omeprazole (Reimer C, et al.
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Does omeprazole raise blood pressure?

Treatment with omeprazole causes endothelial dysfunction without significantly increasing arterial blood pressure.
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Is Nexium better than omeprazole?

Effectiveness. When comparing Nexium to Prilosec, clinical trials found that Nexium tended to outperform Prilosec and other PPIs. Nexium was able to offer the best acid control as well as faster symptom relief. Even so, both medicines are effective and one may work better for another based on individual health factors.
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Why was omeprazole recalled?

Exact lot numbers of the recalled drugs can be found on the FDA's website. The FDA said the medicines may contain "unacceptable" amounts of N-Nitrosodimethylamine (NDMA), a substance the World Health Organization has classified as a "probable human carcinogen."
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How do you feel after stopping omeprazole?

Rebound acid secretion when stopping

When omeprazole is stopped, a common side effect is rebound acid secretion, where the acid secretion in your stomach increases significantly. This should return to normal within 2 weeks.
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How do I wean off omeprazole 20 mg a day?

How To Wean Off PPIs
  1. Step 1: Begin alternating between 1 PPI/day and 2 PPIs/day. On days with 1 PPI, take the PPI with your largest meal. ...
  2. Step 2: After 2 weeks of alternating, reduce intake to approximately 1 PPI/day. ...
  3. Step 3: After about 2 more weeks, you can try to transition off completely.
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Can omeprazole be stopped cold turkey?

Taper your PPI gradually

Many people's first instinct is to slowly cut back on their PPI rather than stopping cold turkey. But one study looked into this and found no difference between these strategies. People who gradually cut back over 3 weeks had just as many side effects as people who stopped suddenly.
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How long can you safely take omeprazole?

You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.
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Can omeprazole cause organ damage?

Omeprazole (Prilosec) is a proton pump inhibitor (PPI) that is used to reduce the amount of acid in your stomach and it can be bad for your kidneys. It can cause acute kidney injury and may also worsen the progression of chronic kidney disease (CKD).
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Is omeprazole a high risk medication?

Long-term omeprazole may be linked to heart problems

There's some research linking long-term PPI use to a greater risk of heart attacks. For example, one review of almost 3 million people with GERD found that long-term PPI use may lead to a greater risk of heart attack.
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