What are the long-term effects of aspartame?

Long-term aspartame administration resulted in many degenerative changes affecting mainly the myelin sheath, in the form of focal and extensive demyelination; disruption and splitting of myelin lamellae with loss of compact lamellar structure; and excessive enfolding with irregular thickening of myelin sheaths.
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Does aspartame cause health problems?

Aspartame hasn't been linked conclusively to any specific health problems, other than for people with phenylketonuria (PKU). This is a rare genetic disorder (present at birth) in which the body can't break down phenylalanine, an amino acid found in many foods (and in aspartame).
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What are the symptoms of too much aspartame?

Breathlessness, elevated blood pressure and skipped or racing heartbeat are all symptoms of aspartame toxicity. Gastrointestinal Symptoms. People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.
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What aspartame does to your brain?

The consumption of aspartame, unlike dietary protein, can elevate the levels of phenylalanine and aspartic acid in the brain. These compounds can inhibit the synthesis and release of neurotransmitters, dopamine, norepinephrine, and serotonin, which are known regulators of neurophysiological activity.
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What kind of cancer does aspartame cause?

No, artificial sweeteners such as aspartame don't cause cancer. You might have seen stories about artificial sweeteners and cancer on social media or the news. But the best evidence in humans does not show a link. The European Food Safety Authority (EFSA) has also reviewed the evidence.
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About Aspartame Side Effect Studies



Is aspartame worse than sugar?

None of the sugars and sweeteners in the study had any negative effect on people with a healthy weight, though. These studies suggest that regular intake of aspartame could increase the risk of glucose intolerance, particularly in people who may already be overweight.
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How much aspartame per day is safe?

The acceptable daily intake of aspartame is 50 mg/kg of body weight per day; this new study suggests that this number may be too high and should be more in the area of 20 mg/kg of body weight. Acceptable Daily Intake: 50 milligrams for each kilogram of body weight.
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Does aspartame Alzheimer's?

These studies found no scientific evidence of a link between aspartame and memory loss. Aspartame was approved by the U.S. Food and Drug Administration (FDA) in 1996 for use in all foods and beverages.
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Does aspartame destroy brain cells?

Aspartame is an excitotoxin and carcinogenic substance. In other words it can cause brain cells to die and can cause cancer. It is metabolized into three distinct components in a human body.
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Does aspartame cause Parkinson's?

According to Mehl-Madrona (2005) aspartame changes the dopamine level in the brain, affecting people suffering from Parkinson's disease. Bowen and Evangelista (2002) noted a substantial increase in the levels of plasma phenylalanine and aspartic acid after ingestion of aspartame.
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How does the body get rid of aspartame?

Aspartame is fully broken down in our gut to aspartic acid and phenylalanine, which are absorbed and enter our body. In addition, the methyl group from the modified phenylalanine is released in the gut to form methanol. Methanol is also absorbed by the body and most of it used to produce energy.
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Does aspartame accumulate in the body?

If the person consumes this substance, the body doesn't digest it properly, and it can accumulate. High levels may result in brain damage. The FDA urges people with this condition to monitor their intake of phenylalanine from aspartame and other sources.
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Is aspartame an inflammatory?

Additives & Artificial Sweeteners

Your body cannot process artificial ingredients well, so substances such as aspartame and mono-sodium glutamate may trigger an immune response. Aspartame is a neurotoxin that the body frequently “attacks” therefore causing inflammation.
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Does aspartame make you gain weight?

Some research indicates that even acceptable daily intakes of aspartame, as regulated by the United States Food and Drug Administration (FDA), might make you hungrier and lead to weight gain.
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Is stevia better than aspartame?

“Stevia leaf extract is safer than many other sugar substitutes, especially aspartame and sucralose,” Lefferts says. Research has linked sucralose, aspartame, and saccharin with cancers. That said, there is still a need for more research around stevia.
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What is the safest artificial sweetener to use?

Aspartame — "safe"

One of the most common sugar substitutes, aspartame is approved for use in more than 90 countries around the world and is used in 6,000 different products, including soft drinks, cereals, breath mints, chewing gum, hard candies.
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Does aspartame cause neuropathy?

It has also been shown that aspartame metabolites induced amino acid imbalance within the neuron microenvironment, thus producing nerve damage [36], [37].
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Can aspartame cause brain fog?

Aspartame. Popular artificial sweetener, a.k.a. Equal® or NutraSweet®. Aspartame is harmful for your brain. Reported side effects include brain fog, migraines, dizziness, memory lapses, anxiety, depression and amplified symptoms of ADHD.
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Does artificial sweetener cause dementia?

Sugar- and artificially-sweetened beverage intake have been linked to cardiometabolic risk factors, which increase the risk of cerebrovascular disease and dementia.
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Can aspartame affect memory?

Aspartame users reported more memory problems than nonusers, especially forgetting that a task was completed until it was started again, forgetting to perform a task at a certain time, or forgetting a regular routine.
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Does aspartame cause cognitive decline?

In another 2017 report published in Nutritional Neuroscience, aspartame was found to be linked to various behavioral and cognitive problems, including learning difficulties, seizures, headaches and migraines, anxiety, depression and insomnia.
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Is aspartame worse than Splenda?

They are both considered generally safe for use within their stated safe limits. Sucralose is a better choice if you have phenylketonuria (PKU), a rare genetic condition, as aspartame contains the amino acid phenylalanine.
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Is aspartame made from poop?

Apparently the E. coli are grown in tanks and, as they defecate, their fecal matter is harvested because it contains aspartic acid-phenylalanine amino acid –the protein needed to make the aspartame. These fecal proteins are then treated with methanol to produce the artificial sweetener.
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Is Coke Zero worse than Coke?

There are very few differences between Diet Coke and Coke Zero. As such, there is no concrete, measurable reason to suggest that one is superior to the other. Nutritionally, there are no significant differences. Their ingredient and caffeine contents are similar as well, so neither is healthier than the other.
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Does Coke Zero have aspartame?

Yes. We sweeten Coke Zero Sugar in our bottles and cans with a blend of aspartame and acesulfame potassium (or Ace-K). Together, they create a great taste with zero sugar and zero calories.
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