What are the common symptoms of Multisystem Inflammatory Syndrome (MIS-C)?

MIS-C can be serious, even deadly, but most children who were diagnosed with this condition have gotten better with medical care.
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Ongoing fever PLUS more than one of the following:
  • Stomach pain.
  • Bloodshot eyes.
  • Diarrhea.
  • Dizziness or lightheadedness (signs of low blood pressure)
  • Skin rash.
  • Vomiting.
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What is multisystem inflammatory syndrome in children (MIS-C)?

Multisystem inflammatory syndrome in children (MIS-C) is a serious condition associated with COVID-19 where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.
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What is the treatment for Multisystem Inflammatory Syndrome in Adults (MIS-A) from COVID-19 in adults?


For now, steroids, IVIG, and supportive care treatments have been suggested in the literature for MIS-A (Ahmad, May 2021; Davogustto, May 2021). Based on current knowledge, CDC recommends COVID-19 vaccination as the best protection from MIS-A.

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Can COVID-19 cause pediatric multisystem inflammatory syndrome (PMIS) in children?

Some children and teens who are in the hospital with the disease have an inflammatory syndrome that may be linked to the new coronavirus. Doctors call it pediatric multisystem inflammatory syndrome (PMIS). Symptoms include a fever, a rash, belly pain, vomiting, diarrhea, and heart problems.
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When was COVID-19 Multisystem inflammatory syndrome in children (MIS-C) first diagnosed?

Multisystem inflammatory syndrome in children (MIS-C) was first identified in April 2020 by doctors at children's hospitals in the United States and the United Kingdom. The condition has also been called pediatric inflammatory multisystem syndrome (PIMS).

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What is multisystem inflammatory syndrome in children in the context of COVID-19?

Multisystem inflammatory syndrome (MIS) is a rare but serious condition associated with COVID-19 in which different body parts become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. MIS can affect children (MIS-C) and adults (MIS-A).
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When was the Omicron variant of COVID-19 detected in the U.S.?


The B.1.1.529 (Omicron) variant, first detected in November 2021, was responsible for a surge in U.S. infections with SARS-CoV-2, the virus that causes COVID-19, during December 2021–January 2022 (1).

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Is multisystem inflammatory syndrome (MIS) associated with COVID-19?

Multisystem inflammatory syndrome (MIS) can affect children (MIS-C) and adults (MIS-A). MIS is a rare but serious condition associated with COVID-19 in which different body parts become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.
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Does having an autoimmune disease make me more susceptible to COVID-19?

However, depending on the autoimmune disorder and the immunosuppressive medication you are taking, you may be more likely to get seriously ill from COVID-19.
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What are the most common reactions to the COVID-19 vaccine in children?


Reactions were reported most frequently on the day after vaccination for both doses. The most frequently reported reactions after either dose were injection site pain, fatigue, and headache. Fever was more frequently reported after dose 2 (4,001; 13.4%) than dose 1 (3,350; 7.9%).

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How long after being infected with COVID-19 can multisystem inflammatory syndrome in adults (MIS-A) occur?

This new and serious syndrome, called multisystem inflammatory syndrome in adults (MIS-A), occurs in adults who were previously infected with the COVID-19 virus and many didn't even know it. MIS-A seems to occur weeks after COVID-19 infection, though some people have a current infection.
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Is there a monoclonal antibody therapy for post COVID-19 exposure?



FDA authorizes bamlanivimab and etesevimab monoclonal antibody therapy for post-exposure prophylaxis (prevention) for COVID-19 | FDA.

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Do nonsteroidal anti-inflammatory drugs (NSAIDs) worsen the course of disease for people with COVID-19?

CDC is currently not aware of scientific evidence establishing a link between NSAIDs (e.g., ibuprofen, naproxen) and worsening of COVID‐19.

FDA, the European Medicines Agency, the World Health Organization, and CDC are continuing to monitor the situation and will review new information on the effects of NSAIDs and COVID-19 disease as it becomes available.

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How do you get Paxlovid?

“Paxlovid is now available at many pharmacies and is government funded during the public health crisis,” Cutler said. “With a prescription from your doctor, Paxlovid is now fairly easily accessible.”
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What conditions put children at higher risk for COVID-19?


Like adults, children with obesity, diabetes, asthma or chronic lung disease, sickle cell disease, or who are immunocompromised can also be at increased risk for getting very sick from COVID-19.

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What are some of the Long-term effects of COVID-19 on children?


Pain, headaches, fatigue, anxiety, depression, fever, cough and sleep problems have all been reported,” said Lawrence Kleinman, a professor and vice chair of the Department of Pediatrics at RWJMS and a professor of global public health at the Rutgers School of Public Health and lead investigator for the Collaborative

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Should you get the Covid vaccine if you have an autoimmune disease?

The American College of Rheumatology COVID-19 Vaccine Clinical Guidance recommends that people with autoimmune and inflammatory rheumatic disease (which includes lupus) get the vaccine unless they have an allergy to an ingredient in the vaccine.
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Which groups of people are at increased risks of severe illness from COVID-19?

Among adults, the risk for severe illness from COVID-19 increases with age, with older adults at highest risk. Severe illness means that the person with COVID-19 may require hospitalization, intensive care, or a ventilator to help them breathe, or they may even die. People of any age with certain underlying medical conditions are also at increased risk for severe illness from SARS-CoV-2 infection.
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Are you at risk of experiencing an autoimmune disease flare-up from COVID-19 vaccine?

There is a risk that flare-ups may occur. That being said, it has been observed that people living with autoimmune and inflammatory conditions are at higher risk of experiencing severe symptoms from a COVID-19 infection.
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What other illnesses are caused by coronaviruses?

Coronavirus is a family of viruses that can cause respiratory illnesses such as the common cold, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).
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Which organ system is most often affected by COVID-19?

COVID-19 is a disease caused by SARS-CoV-2 that can trigger what doctors call a respiratory tract infection. It can affect your upper respiratory tract (sinuses, nose, and throat) or lower respiratory tract (windpipe and lungs).
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Can COVID-19 cause other neurological disorders?

In some people, response to the coronavirus has been shown to increase the risk of stroke, dementia, muscle and nerve damage, encephalitis, and vascular disorders. Some researchers think the unbalanced immune system caused by reacting to the coronavirus may lead to autoimmune diseases, but it's too early to tell.
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Does the Omicron COVID-19 variant cause more severe disease?


Omicron infection generally causes less severe disease than infection with prior variants. Preliminary data suggest that Omicron may cause more mild disease, although some people may still have severe disease, need hospitalization, and could die from the infection with this variant.

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Is there a difference in spread between the Omicron and Delta COVID-19 variant?


The Omicron variant spreads more easily than earlier variants of the virus that cause COVID-19, including the Delta variant. CDC expects that anyone with Omicron infection, regardless of vaccination status or whether or not they have symptoms, can spread the virus to others.

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Where was the COVID-19 IHU variant discovered?


The IHU variant, officially known as B.1.640.2, was named by researchers who discovered it in a male patient at the Méditerranée Infection University Hospital Institute (IHU) in France.

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