What are long-term effects of taking gabapentin?

According to researchers, long-term use of gabapentin — a nonopioid pain medication — among older adults may cause altered mental status, dizziness, drowsiness and renal dysfunction, and it could also lead to polypharmacy, which in itself can lead to adverse events and hospital stays.
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How long can I safely take gabapentin?

According to the World Health Organization (WHO), “the efficacy and safety of gabapentin have not been examined in clinical studies for treatment periods longer than five months.” However, gabapentin can be taken longer than five months, should a treating physician deem it necessary, provided the patient does not ...
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Can you be on gabapentin for years?

There was no evidence to suggest dosing difficulties due to tolerance over the 3-year period. Sedation, dizziness, and forgetfulness were the most common side effects. Conclusions: Gabapentin may be an effective treatment of pain after spinal cord injury among those able to tolerate initial and long-term side effects.
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Can you stay on gabapentin for life?

It might last for a full week, if not longer, and the person's symptoms will likely require the most time and care to endure. Due to this, people should not attempt to discontinue gabapentin without proper medical supervision.
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What are the dangers of using gabapentin?

Gabapentin may cause vision changes, clumsiness, unsteadiness, dizziness, drowsiness, sleepiness, or trouble with thinking. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well.
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Gabapentin Side Effects - What You Need To Know Now



Can you take gabapentin long-term for nerve pain?

Gabapentin is used to manage long-term (chronic) pain, not to be taken for pain as needed. Chronic pain can interfere with sleep and work, and lead to depression. Studies show that pain relief may start within one week and reach a maximum effect in about 4 weeks.
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Does gabapentin damage the brain?

This study found that not only can Gabapentin cause memory loss when abused, but it can also lead to other cognitive problems that can contribute to memory impairment. Also, Gabapentin's long-term use side effects present other dangers, such as weakened muscles, fatal toxicity, and respiratory failure.
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Does gabapentin damage the kidneys?

Gabapentin does not directly influence or damage the kidney. You should check with your physician about the dose of Gabapentin that you are taking.
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Will gabapentin make you gain weight?

Although they're not common side effects, gabapentin has been reported to potentially cause weight gain and fluid buildup in the legs (edema). If you're taking gabapentin or another medication that you think may have led to gaining a few extra pounds, talk to your healthcare provider.
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Does gabapentin make you lose your memory?

Gabapentin may cause other long-term effects, including memory loss, weakened muscles, and respiratory failure.
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What drugs Cannot be taken with gabapentin?

Cautions with other medicines
  • strong painkillers, such as morphine – these can make you very tired and dizzy when you start taking gabapentin.
  • antidepressants, such as amitriptyline or fluoxetine.
  • antipsychotic medicines for mental health problems like schizophrenia or bipolar disorder.
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How do you get off of gabapentin?

Tapering or slowly reducing your dose is the recommended way to stop taking gabapentin. Tapering off will help you avoid side effects. The timeline to reduce gabapentin depends on the individual and the current dose of the medication. Your doctor will develop a plan to slowly take you off the medication.
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Does gabapentin cause heart problems?

Background: Gabapentin is a commonly used medication used as an anti-convulsant or analgesic. The well-known side-effects of gabapentin are dizziness, drowsiness and fatigue. In rare cases, it can lead to development of new onset congestive heart failure (CHF) or decompensation of pre-existing CHF.
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Is 300mg of gabapentin a lot?

Adults and children 12 years of age and older—At first, 300 milligrams (mg) three times per day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 1800 mg per day (600 mg three times per day).
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Does gabapentin help with arthritis pain?

Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis.
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Is it better to take gabapentin at night?

You can take gabapentin with or without food, but it's best to do the same each day. Try to space your doses evenly through the day. For example, you could take it first thing in the morning, early afternoon and at bedtime.
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Does gabapentin affect your liver?

Gabapentin, a gamma-aminobutyric acid (GABA) analogue, has infrequently been reported to cause liver injury; however, the causality in the previous reports is contested. Herein, we report a gabapentin-induced hepatocellular injury in a patient without another identifiable cause for acute liver injury.
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Does gabapentin cause belly fat?

Official answer. Gabapentin may cause weight gain, but it is a rare side effect. Studies have shown that a small number of people taking gabapentin, a drug used to treat epilepsy and postherpetic neuralgia, experienced weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use.
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Can you drink coffee when taking gabapentin?

Coffee doesn't directly interact with gabapentin (Neurontin), so if you're taking the medication for nerve pain it's ok to drink coffee (the medication itself should be taken with water).
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Can gabapentin cause organ damage?

In summary, we can conclude that although it happens infrequently, gabapentin may cause myotoxicity, rhabdomyolysis and renal failure even in patients whose renal function was previously normal.
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Can you stop gabapentin cold turkey?

If the drug is suddenly stopped “cold turkey” rather than tapering off it, withdrawal symptoms can result. Stopping neurontin suddenly may cause an increase in seizure activity in those who have seizure disorders. Other potential symptoms of gabapentin withdrawal may include: Sweating.
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What are the benefits of gabapentin?

Gabapentin is in a class of medications called anticonvulsants. Gabapentin treats seizures by decreasing abnormal excitement in the brain. Gabapentin relieves the pain of PHN by changing the way the body senses pain.
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Can gabapentin affect you mentally?

For older patients initiated on gabapentin, the overall risk of being hospitalized with altered mental status was found to be low, according to a study published in PLOS One. While effective in treating chronic neuropathic pain, gabapentin may be associated with dizziness, drowsiness, and confusion in some adults.
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Does gabapentin affect your bowels?

Conclusion: Our results show that gabapentin reduces rectal sensory thresholds through attenuating rectal sensitivity to distension and enhancing rectal compliance in diarrhoea-predominant irritable bowel syndrome patients. The clinical efficacy of this drug in irritable bowel syndrome patients warrants investigation.
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Can gabapentin cause neurological problems?

A loss of balance found to be associated with Gabapentin can be dangerous as it could easily lead to other injuries. Patients and physicians need to be aware of the unusual neurologic side effects with the use of Gabapentin.
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