Should you take vitamin B12 when taking metformin?

Should you take a supplement? Messer says taking a supplement can treat the deficiency and prevent further nerve damage while still taking metformin as prescribed. A normal B12 level is considered anywhere between 190 and 900 nanograms per milliliter (ng/mL), but Messer suggests treating any level below 300 ng/mL.

Should I take vitamin B12 with metformin?

Low levels of vitamin B12 can cause serious and sometimes permanent neurological damage, as well as bone marrow production issues with subsequent anemia. This is why levels of this nutrient must be monitored in anyone taking metformin.

How does vitamin B12 affect metformin?

In another study, metformin dose had a negative relationship with vitamin B12 levels, and an increase of 1 mg in the daily metformin dose was associated with a 0.042 pg/mL decrease in vitamin B12 levels, but the duration of metformin use did not show significant effects.

How much B12 should a diabetic take a day?

In the US, it is currently believed that adults with type 2 diabetes that are over 50 should take 2.4 µg of synthetic vitamin B12 daily either in supplement form or in fortified food.

Does metformin cause vitamin B12 deficiency?

Years of metformin use were associated with increased risk of B12 deficiency (odds ratio, B12 deficiency/year metformin use, 1.13; 95% confidence interval, 1.06–1.20). Anemia prevalence was higher in MET, but did not differ by B12 status. Neuropathy prevalence was higher in MET with low B12 levels.

Metformin and Vitamin B12 Deficiency

Should a diabetic take vitamin B12?

A B12 supplement can be helpful if you have type 2 diabetes and are deficient in the vitamin. People who take metformin for type 2 diabetes have lower levels of vitamin B12.

What vitamins should I take with metformin?

Metformin therapy has been shown to deplete vitamin B12, and sometimes, but not always, folic acid as well. People taking metformin should supplement vitamin B12 and folic acid or ask their doctor to monitor folic acid and vitamin B12 levels.

Can vitamin B12 affect blood sugar?

With B12 supplementation homocysteine level can be reduced . Type 2 diabetes as a metabolic syndrome may show improvement in glycaemic control with Vitamin B12 therapy as there is correction of hyperhomocysteinemia.

What are the symptoms of low B12?

What medications should not be taken with B12?

Certain medications can decrease the absorption of vitamin B12, including: colchicine, metformin, extended-release potassium products, antibiotics (such as gentamicin, neomycin, tobramycin), anti-seizure medications (such as phenobarbital, phenytoin, primidone), medications to treat heartburn (such as H2 blockers ...

Is 1000 mg of B12 too much daily?

Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population.

What are the best vitamins for diabetics?

Can you take vitamin D with metformin?

No interactions were found between metformin and Vitamin D3.

How much B12 do I need with metformin?

All individuals age 14 or higher need 2.4 mcg B12 daily. Women who are pregnant or nursing will need slightly more. Mandatory supplementation with B12 has now been proposed for those taking metformin. Taking a daily multivitamin containing 100% of the daily value (DV) for vitamin B12 will do the trick.

Is it good to take vitamin B12 tablets?

Vitamin B12 is a water-soluble vitamin that you must obtain through diet or supplements. It's responsible for many bodily functions and may benefit your health in various ways, such as by preventing major birth defects, supporting bone health, improving mood and maintaining healthy skin and hair.

Can you take too much vitamin B12?

Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population.

Is B12 deficiency related to diabetes?

There are other ways to develop a deficiency. For example, having diabetes mellitus can increase your risk of having a B-12 deficiency because it may be a side effect of metformin, a common treatment for type 2 diabetes mellitus. A 2009 study found that 22 percent of people with type 2 diabetes were low in B-12.

Does vitamin B12 increase blood pressure?

We found that a higher intake of vitamin B12 was associated with lower systolic and diastolic blood pressure and a higher intake of folic acid was associated with lower systolic blood pressure in children.

Which vitamins reduce blood sugar?

What should I avoid while taking metformin?

Other things to avoid while on metformin

diuretics, such as acetazolamide. corticosteroids, such as prednisone. blood pressure medication, such as amlodipine (Norvasc) anticonvulsants, such as topiramate (Topamax) and zonisamide (Zonegran)

What can you not mix with metformin?

Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran).

Can I take a multivitamin while on metformin?

No interactions were found between Daily Multi-Vitamins with Minerals and metformin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

What does vitamin B12 do for diabetics?

Vitamin B12 replacement has been shown to cause symptomatic improvement among patients with severe diabetic neuropathy. One meta-analysis showed that if used either alone or in combination with vitamin B complex, there was a significant improvement in the somatic symptoms like pain and paraesthesias.

What supplements are good for diabetes type 2?