Should I be worried about granuloma annulare?

Because granuloma annulare usually causes no symptoms and clears up by itself, you may not need treatment (except for cosmetic reasons). It is not contagious. If you do receive treatment, it may include corticosteroids (cream, tape, or injections).
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Is granuloma annulare life threatening?

Granuloma annulare is a benign (not cancer), often chronic (long-lasting) skin disorder in which inflammation in the skin causes a raised, discolored rash or lumps under the skin. In most cases, rashes form on the hands, feet and forearms.
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Is granuloma annulare harmless?

Granuloma annulare is a harmless type of skin rash. The rash is most often discolored and raised, and roughly in the shape of a ring. The rash may be on just one part of the body. Or it may appear on more than one area of the body and become widespread (generalized).
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Is granuloma annulare a rare condition?

The disorder can affect people of any age, but occurs most frequently in children and young adults. The prevalence of granuloma annulare in the general population is unknown. Localized granuloma annulare occurs more often than the others forms.
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What cancers cause granuloma annulare?

Which malignancies have been associated with granuloma annulare?
  • Non-Hodgkin lymphoma.
  • Hodgkin lymphoma.
  • Acute myelogenous leukemia.
  • Chronic lymphocytic leukemia.
  • Myelomonocytic leukemia.
  • Large granular lymphocytic leukemia.
  • Myelodysplastic syndrome.
  • T-cell lymphoma.
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Granuloma annulare: treatments and causes: dermatologist Dr Dray



What can be mistaken for granuloma annulare?

Granuloma annulare can be mistaken for other common annular skin conditions such as tinea corporis, pityriasis rosea, nummular eczema, psoriasis, or erythema migrans of Lyme disease. The lack of any surface changes to the skin is the key feature that distinguishes granuloma annulare from these other skin conditions.
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Are granulomas tumors?

Are granulomas cancerous? Although granulomas may appear cancerous, they are not — they are benign. Occasionally, however, granulomas are found in people who also have particular cancers, such as skin lymphomas.
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Does stress cause granuloma annulare?

Some reports associate chronic stress with granuloma annulare as a trigger of the disease. Granuloma annulare also has some predilection for the sun-exposed areas and photodamaged skin.
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What autoimmune disease causes granuloma annulare?

Granuloma annulare is occasionally associated with diabetes or thyroid disease, most often when lesions are numerous or widespread. It may, rarely, be related to cancer, especially in older people whose granuloma annulare is severe, doesn't respond to treatment or returns after cancer treatment.
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What are the side effects of granuloma?

Granulomas themselves don't usually have noticeable symptoms. But the conditions that cause them, such as sarcoidosis, tuberculosis, histoplasmosis, and others, may create symptoms.
...
Some of these include:
  • Shortness of breath.
  • Wheezing.
  • Chest pain.
  • Fever.
  • Dry cough that won't go away.
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How do you stop granuloma annulare from spreading?

Treatment options include:
  1. Corticosteroid creams or ointments. Prescription-strength products may help improve the appearance of the bumps and help them disappear faster. ...
  2. Corticosteroid injections. ...
  3. Freezing. ...
  4. Light therapy. ...
  5. Oral medications.
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How do you calm granuloma annulare?

Light therapy: Exposing the skin with granuloma annulare to ultraviolet (UV) light in a controlled way can be helpful. Some people receive a type of light therapy called PUVA. This involves taking a medication called psoralen and then treating the skin with UVA light.
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What drugs may cause granuloma annulare?

Various drugs which have been implicated in etiology of granuloma annulare include amlodipine, gold, allopurinol, diclofenac, quinidine and intranasal calcitonin.
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Does granuloma annulare come and go?

Most granuloma annulare rashes resolve without treatment within 2 years. However, it is not uncommon to have new rings appear years later.
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How serious is granuloma?

People with chronic granulomatous disease experience serious bacterial or fungal infection every few years. An infection in the lungs, including pneumonia, is common. People with CGD may develop a serious type of fungal pneumonia after being exposed to dead leaves, mulch or hay.
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Can a granuloma become cancerous?

Calcified granulomas are almost always benign. However, less commonly, they can become surrounded by a cancer tumor.
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Can granulation tissue cancerous?

It may also occur in the chest, breast, esophagus, stomach, or other internal organ. Most granular cell tumors are benign (not cancer), but some may be malignant (cancer) and spread quickly to nearby tissue. They usually occur in middle-aged adults. Also called Abrikossoff tumor.
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Is granuloma annulare genetic?

Granuloma annulare--a genetic disorder that sustain an incomplete foreign-body granuloma reaction.
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Is granuloma annulare an autoimmune disorder?

This association certainly supports the theory that granuloma annulare is within the spectrum of autoimmune diseases. It turns out that both disorders share the histocompatibility HLA-Bw35 antigen in some patients.
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Can diet help granuloma annulare?

A diagnosis of generalized erythematous granuloma annulare was established based on the clinical and histopathological findings, especially with the distribution on more than one anatomic site. A lipid-lowering diet for three months resulted in major improvement of hyperlipidemia and remission of the skin lesions.
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Can granuloma annulare be cancerous?

Generalized granuloma annulare can be associated with breast cancer. Atypical granuloma annulare especially in older patients should alert physicians to the possibility of an occult malignancy.
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Is granuloma annulare related to diabetes?

Granuloma annulare (GA) is usually a self-limited, benign granulomatous disease of the dermis and subcutaneous tissue. It's generalized or disseminated form is associated with underlying diabetes mellitus and at times it precedes the sign and symptoms of diabetes mellitus.
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Is granuloma annulare a fungal infection?

Granuloma Annulare-like Skin Lesion due to Fusarium roseum: Therapy With Ketoconazole. To the Editor. — Species of Fusarium are important plant pathogens and common soil fungi and are usually considered opportunistic fungi in humans.
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What viral infections cause granuloma annulare?

Granuloma annulare has been hypothesized to be associated with tuberculosis, insect bites, trauma, sun exposure, thyroiditis, vaccinations, and viral infections, including HIV, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, and herpes zoster virus.
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Are granulomas permanent?

In most cases, skin granulomas will go away on their own without treatment. Sometimes, though, they might come back. Underlying health conditions can also cause granulomas. When this is the case, doctors will focus on treating the underlying cause of the lumps.
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