Should CIN 2 be treated?

CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated. Treatment for CIN 2 may include cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue. CIN 2 is sometimes called high-grade or moderate dysplasia.

Does CIN 2 always need treatment?

Right now, CIN2 is typically treated. But some studies have suggested that CIN2 lesions often regress completely without treatment and should therefore be simply monitored instead.

What are the chances of CIN 2 turning into cancer?

Approximately 60% of CIN 1 lesions regress without treatment and less than 1% progress to cancer. However, it is estimated that 5% of CIN 2 and 12% of CIN 3 cases will progress to invasive cancer if untreated.

Will CIN 2 Go Away?

CIN 2 lesions often clear up on their own, but can also progress to CIN 3 lesions. CIN 3 is the most severe. It's a very slow-growing disease, though: fewer than half of CIN 3 lesions will have become cancer within 30 years.

What is the best treatment for CIN 2?

laser or loop electrosurgical excision procedure (leeP) are the preferred treatment methods for recurrent CIN 2 and CIN 3 (sor: B, based on clinical trials without randomization).

What is CIN

Does CIN 2 mean I have HPV?

CIN 2 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated.

Does HPV always cause CIN 2?

No, HPV (human papillomavirus) causes an infection that can lead to CIN, but they are not the same.

How long does it take for CIN 2 to regress?

Conclusion: CIN2 lesions regress without treatment in one year, although an ablative procedure is more effective.

How long does it take for CIN 2 to go away?

In a meta-analysis of 36 studies (both randomized trials and observational studies) including 3160 patients with CIN 2, at 24 months, lesions regressed in 50 percent of patients, persisted in 32 percent, and progressed to CIN 3+ in 18 percent [14].

What type of HPV causes CIN 2?

Results: HPV was detected in 92.9% of women with CIN 2-3 and high-risk HPV (HR-HPV) was detected in 85.8% of them. In women with cervical cancer, HPV was positive in 96.5%, HR-HPV detected in 93%.

How can I get rid of cervical dysplasia naturally?

How long does it take for abnormal cervical cells to turn into cancer?

Cervical cancer develops very slowly. It can take years or even decades for the abnormal changes in the cervix to become invasive cancer cells. Cervical cancer might develop faster in people with weaker immune systems, but it will still likely take at least 5 years.

Can you still get cervical cancer after LEEP procedure?

LEEP does not completely eradicate HPV infection. HPV persistence rate after LEEP is higher in infections with type 16 and in women older than 36.5 years.

Should I get a hysterectomy if I have precancerous cells?

If the precancerous disease is more extensive or involves adenocarcinoma in situ (AIS), and the woman has completed childbearing, a total hysterectomy may be recommended. 1 During a total hysterectomy, the entire uterus (including the cervix) is removed.

Can you get pregnant on CIN 2?

The results suggest that treatment for CIN does not adversely affect the chances of a successful conception, although treatment is associated with an increased risk of miscarriage in the second trimester.

How serious are precancerous cells?

Often, precancerous lesions are not invasive and a person will not develop cancer. In some cases these precancerous cells, if left alone, may go on to become “invasive” cancer cells. Sometimes, it may take these cells a few years, or even decades to progress.

Can HPV come back after LEEP?

Results. In our study, the rate of persistent infection from HPV 16, after LEEP, was 15.9% (29/182) with 94% (17/18) of the recurring disease occurring within 18 months of follow up.

What happens if CIN 2 is left untreated?

High-Grade Abnormalities CIN-2 & CIN-3

These cells are more likely to become cancerous and invade deeper layers of the cervix if left untreated. If high-grade abnormalities are detected on a Pap smear, the woman is advised to have a colposcopy and biopsy.

How long does it take HPV to turn into CIN 2?

CIN2/3 incidence

The time from HPV infection to CIN2/3 development was assumed to follow an exponential distribution and to be independent of age at infection. Its mean value was also determined using the POBASCAM data and was estimated at 3.0 years (see Supplementary Data).

Why do I need a second LEEP procedure?

In some instances, you may need a repeat procedure to remove all the cells completely. You may also need an additional LEEP if abnormal cells return. You're at a greater risk of recurrence if you're infected with a high-risk strain of the human papillomavirus, or HPV.

Do I need a colposcopy if I have HPV?

If you test positive for HPV 16/18, you will need to have a colposcopy. If you test positive for HPV (but did not have genotyping performed or had genotyping and tested negative for 16/18), you will likely have a colposcopy.

Will removing the cervix cure HPV?

Surgically treating genital warts doesn't cure a human papillomavirus (HPV) infection, however, and warts can return after surgery if the immune system does not eliminate the infection. Surgery may be used to treat moderate to severe cervical dysplasia by removing abnormal cells on the cervix.

Is CGIN worse than CIN?

CGIN is usually classified as low grade (mild) or high grade (severe). High grade CGIN is the equivalent of CIN3. CGIN can be multi-focal – this means that more than one area is affected at one time, with normal tissue lying between them.

What percentage of LEEP procedure shows cancer?

Results. The colposcopic guided LEEP accurately determined 100% of the cervical cancer cases and 84.8 % of the high-grade squamous intraepithelial lesion cases. Involvement of the ectocervical or endocervical margin regions was found to be 5% and 10% respectively, in this study.

What is the next step after a LEEP procedure?

The most common next step after a LEEP procedure is to get a pap smear in six months. It is Really Important to get a follow-up pap smear, after the LEEP procedure.