Should a statin and CoQ10 be taken together?

Some researchers have suggested that low levels of coenzyme Q10 can lead to the muscle aches that can be associated with statin use. With that in mind, coenzyme Q10 supplements have sometimes been recommended for people who take statins.
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How much CoQ10 should I take with statins?

For people taking statin medications, the typical dosage recommendation for CoQ10 is 30–200 mg per day ( 13 ).
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When should I take CoQ10 morning or night?

CoQ10 is fat soluble, so it should be taken with a meal containing fat so your body can absorb it. Also, taking CoQ10 at night may help with the body's ability to use it.
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Can you take atorvastatin and CoQ10 together?

No interactions were found between atorvastatin and CoQ10. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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What medications should not be taken with statins?

Some drugs that may interact with statins and increase your risk of side effects include:
  • Amiodarone (Cordarone, Pacerone), a medication for irregular heart rhythms.
  • Gemfibrozil (Lopid), another variety of cholesterol drug.
  • HIV treatments called protease inhibitors such as saquinavir (Invirase) and ritonavir (Norvir)
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Does Coenzyme Q10 Supplementation Reduce Statin Side Effects?



Can you take vitamin D and statins together?

Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
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What can I take instead of statins to lower cholesterol?

7 cholesterol-lowering alternatives to statins
  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis. ...
  • Plant stanols and sterols. ...
  • Cholestyramine and other bile acid-binding resins. ...
  • Niacin. ...
  • Policosanol. ...
  • Red yeast rice extract (RYRE) ...
  • Natural products.
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What medications should not be taken with CoQ10?

Coenzyme Q10 has no known severe, serious, or moderate interactions with other drugs.
...
What Other Drugs Interact with Coenzyme Q10?
  • atorvastatin.
  • fluvastatin.
  • glyburide.
  • insulin aspart.
  • insulin detemir.
  • insulin glargine.
  • insulin glulisine.
  • insulin lispro.
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Who should not take CoQ10?

They include diarrhea, nausea, and heartburn. Risks. People with chronic diseases such as heart failure, liver problems, or diabetes should be wary of using this supplement. CoQ10 may lower blood sugar levels and blood pressure.
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Which statins must be taken at bedtime?

To maximize the effects of statins with a short half-life, fluvastatin, lovastatin, and simvastatin should be dosed at bedtime allowing the greatest drug concentration to be present during peak endogenous cholesterol synthesis.
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Can I take CoQ10 with vitamin D?

Interactions between your drugs

No interactions were found between CoQ10 and Vitamin D3.
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Can CoQ10 lower cholesterol?

Although more studies are needed, some research suggests that CoQ10 may help reduce low-density lipoprotein (LDL) cholesterol and total cholesterol levels in people with diabetes, lowering their risk of heart disease.
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What supplements to take with statins?

CoQ10 Supplements

Coenzyme Q10 (CoQ10), a nutrient produced by the body and used for cellular energy, is often touted as being vital if you're taking statin drugs to lower cholesterol.
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Why do statins have to be taken at night?

So, why do people take statins at night? Many statins work more effectively when they are taken at night. This is because the enzyme which makes the cholesterol is more active at night. Also, the half-life, or the amount of time it takes for half the dose to leave your body, of some statins is short.
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What does Dr Oz say about CoQ10?

Heart Disease

Since the 1970s, clinical studies have shown that the oral administration of CoQ10 improves the health of patients suffering from heart problems. An analysis of heart muscle tissue collected from patients with heart disease revealed a marked decrease in the tissue CoQ10 concentration.
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Do doctors recommend CoQ10?

However, “there are currently doctors recommending CoQ10 supplements in addition to established treatments such as statins, as the supplements are generally recognized as safe, and potentially beneficial,” Peart says.
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Which is better for heart CoQ10 or fish oil?

Both fish oil and CoQ10 are best known for their heart-healthy benefits. Fish oil naturally regulates the level of inflammation in your body, and it may help fight high levels of inflammation that are linked to cardiovascular disease.
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What are the symptoms of low CoQ10?

Other neurological abnormalities that can occur in primary coenzyme Q10 deficiency include seizures, intellectual disability, poor muscle tone (hypotonia), involuntary muscle contractions (dystonia), progressive muscle stiffness (spasticity), abnormal eye movements (nystagmus), vision loss caused by degeneration ( ...
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Are there side effects to taking CoQ10?

While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can cause allergic skin rashes in some people. It also might lower blood pressure, so check your blood pressure carefully if you have very low blood pressure.
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Does CoQ10 interfere with blood pressure meds?

Medications for high blood pressure (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination. Talk with your health provider. Coenzyme Q-10 seems to decrease blood pressure. Taking coenzyme Q-10 along with medications for high blood pressure might cause your blood pressure to go too low.
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Why does CoQ10 make me feel weird?

Supplement Interactions

CoQ10 may increase vitamin A levels, which may increase the likelihood of vitamin A side effects, such as fatigue or irritability.
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Does CoQ10 cause heart palpitations?

Research indicates that supplementing with CoQ10 or magnesium may provide palpitation relief in some individuals. One study investigating the effects of CoQ10 on heart failure found that 50 mg/day for 4 weeks led to a reduction in heart palpitations in participants.
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Why do doctors push statins?

Statins are the go-to treatment option for lowering cholesterol levels and risk of cardiovascular complications, like heart attack and stroke. Statins work by slowing down cholesterol production and enabling the liver to remove low-density lipoproteins (LDL), or “bad cholesterol,” from the bloodstream.
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What is better than a statin?

Statins are a group of medications that lower a specific type of cholesterol level in your blood. The best alternatives to statins are PCSK9 inhibitors, fibric acid derivatives or fibrates, bile acid sequestrants, selective absorption inhibitors, nicotinic acid or niacin, and omega-3 fatty acids and fatty-acid esters.
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Do statins shorten your life?

A controversial new study found that high cholesterol does not shorten life span and that statins are essentially a “waste of time,” according to one of the researchers. Previous studies have linked statins with an increased risk of diabetes.
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