Is weight gain a side effect of omeprazole?

Significant weight gain has been linked with years-long use of omeprazole and other PPIs (proton pump inhibitors) to treat heartburn or GERD symptoms. The reasons are unclear but are thought to possibly be due to increased food consumption when symptoms are better controlled.
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Does omeprazole cause bloating and weight gain?

PPIs have been reported to cause weight gain. That being said, weight gain isn't a common side effect. It also seems to be more likely when you take PPIs long term. One study found that long-term use of omeprazole, rabeprazole, or lansoprazole was associated with weight gain.
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Do acid reducers cause weight gain?

Yes, Nexium and other heartburn drugs may cause weight gain — as can other drugs, such as certain antidepressants, beta-blockers, and antihistamines. You should talk to your doctor or pharmacist before starting any medication so you understand all the potential side effects of any drug you take.
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Can you lose weight while taking omeprazole?

Since omeprazole treats conditions that cause digestive symptoms, you may have a reduced appetite. This could lead to weight loss. So if your condition improves with omeprazole treatment, your appetite may increase. This could lead to weight gain.
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What is most common side effect of omeprazole?

The most common omeprazole side effect is headache. But it can also cause stomach-related side effects, such as nausea, vomiting, or diarrhea. Taking omeprazole at high dosages, or for longer than a year, raises the risk of more serious side effects. These can include bone breaks and pneumonia (a lung infection).
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Is There a Connection between Omeprazole and Weight Gain



What happens when you stop taking omeprazole?

Stopping omeprazole

But if you've been taking omeprazole for a long time, speak to your doctor before you stop taking it. Stopping suddenly could make your stomach produce a lot more acid, and make your symptoms come back. Reducing the dose gradually before stopping completely will prevent this happening.
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What is considered long term use of omeprazole?

In a clinical context, use of PPI for more than 8 weeks could be a reasonable definition of long-term use in patients with reflux symptoms and more than 4 weeks in patients with dyspepsia or peptic ulcer.
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Do proton pump inhibitors cause weight gain?

Undesired body weight gain was observed in GERD patients on long-term PPI treatment. Reflux patients treated with a daily maintenance therapy of PPI should be strongly encouraged to manage their body weight through lifestyle modifications such as proper diet and avoidance of overeating.
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What are the long-term effects of taking omeprazole daily?

Long-term side effects

Taking omeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
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What foods to avoid while taking omeprazole?

Food Tips when taking Omeprazole:

Greasy or fatty foods like french fries, pizza, deep fried chicken slow the digestive system down and often causes indigestion, heartburn and nausea. Onions, garlic, chocolate, coffee, peppermint and some spices can also cause an increase in gastric symptoms.
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Why am I gaining weight on my stomach?

If you eat too much and exercise too little, you're likely to carry excess weight — including belly fat. Also, your muscle mass might diminish slightly with age, while fat increases.
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How long can you safely take omeprazole?

You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.
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Can long term use of omeprazole cause stomach problems?

Taking omeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk. If you use omeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency.
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Does omeprazole make you poop more?

While most people do just fine on the medication, diarrhea is one of the most common side effects of omeprazole, Ravella says. Loose stools are never fun, but they should clear up on their own. If you're constantly tethered to the toilet, or if you see blood in your stool, it's time to give your doctor a call.
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What is the longest you should take omeprazole?

You shouldn't take OTC omeprazole for longer than 14 days without a healthcare provider's OK. Prescription omeprazole is often taken for 4 to 8 weeks, depending on what you're treating. For some conditions, it's taken for even longer. Taking omeprazole for too long can lead to serious side effects.
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Can you take omeprazole everyday for years?

Although most clinical studies on long-term treatment with omeprazole or other proton pump inhibitors do not report serious adverse effects, the issue of prolonged hypergastrinemia and tissue growth is unsettled, and many clinicians are reluctant to recommend long-term use of omeprazole or of other proton pump ...
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How do I wean off 40 mg omeprazole?

How To Wean Off PPIs
  1. Step 1: Begin alternating between 1 PPI/day and 2 PPIs/day. On days with 1 PPI, take the PPI with your largest meal. ...
  2. Step 2: After 2 weeks of alternating, reduce intake to approximately 1 PPI/day. ...
  3. Step 3: After about 2 more weeks, you can try to transition off completely.
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Does GERD cause weight gain?

GERD (gastroesophageal reflux disease) has been directly linked to even small gains in body weight, without the person having to be overweight, say researchers in a report published in the New England Journal of Medicine, June 1 issue. One of the symptoms of GERD is heartburn.
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What are 2 side effects of using prescribed proton pump inhibitors?

Patients have experienced few minor side effects of short-term PPI use, such as headache, rash, dizziness, and gastrointestinal symptoms including nausea, abdominal pain, flatulence, constipation, and diarrhea.
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Do proton pump inhibitors cause fluid retention?

Proton-pump inhibitors (PPIs) that treat acid reflux and heartburn may increase the risk for loss of brain function and fluid buildup in the abdomen, a study found.
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Why do I have to take omeprazole for life?

Keep in mind that omeprazole is only intended for short-term treatment of heartburn, GERD, and other gastrointestinal conditions. Long-term use is only advised for people with rare medical conditions that cause hypersecretion of stomach acid.
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How long can you take omeprazole 20 mg for?

To treat gastroesophageal reflux disease (GERD) for erosive esophagitis: Adults—20 milligrams (mg) once a day for 4 to 8 weeks. Children—Use and dose must be determined by your doctor.
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Can you quit omeprazole cold turkey?

Taper your PPI gradually

Many people's first instinct is to slowly cut back on their PPI rather than stopping cold turkey. But one study looked into this and found no difference between these strategies. People who gradually cut back over 3 weeks had just as many side effects as people who stopped suddenly.
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