Is vitamin D3 toxic?

Vitamin D supplements are considered very safe, and toxicity is uncommon. This is because a healthy person would need to take extremely large doses of vitamin D over time in order to reach toxic or dangerous levels in the body ( 5 ). However, vitamin D toxicity

vitamin D toxicity

Vitamin D toxicity, or hypervitaminosis D is the toxic state of an excess of vitamin D. The normal range for blood concentration is 20 to 50 nanograms per milliliter (ng/mL). However, the toxic state is known to be a value of 100 ng/ml or more in a clinical setting. Vitamin D toxicity.

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Vitamin D toxicity - Wikipedia

is more common in people with certain medical conditions.

How much vitamin D3 is considered toxic?

Taking 60,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the U.S. Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day.

What are the negative effects of vitamin D3?

How much vitamin D3 can you safely take daily?

Unless your doctor recommends it, avoid taking more than 4,000 IU per day, which is considered the safe upper limit.

Can I take 5000 IU of vitamin D3 everyday?

In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe.

Vitamin D Toxicity (Hypervitaminosis D) | Causes, Pathophysiology, Symptoms, Diagnosis, Treatment

What happens if you take too much vitamin D3?

Symptoms and treatment of vitamin D toxicity

Early symptoms of hypercalcemia include nausea, vomiting, diarrhea, constipation, and weakness ( 27 ). Excessive thirst, an altered level of consciousness, high blood pressure, calcification in the kidney tubes, kidney failure, or hearing loss may also develop ( 4 , 28 ).

Who should not take vitamin D3?

Can vitamin D3 cause kidney stones?

Increased vitamin D levels may prevent a wide range of diseases, according to recent studies.

Is 10000 IU of D3 too much?

The Endocrine Society Practice Guidelines recommend that up to 10,000 IUs daily was safe for adults. This is in contrast to the recommended UL at 4,000 IU/d from the IOM.

How do you know if your vitamin D is toxic?

Confusion, apathy, recurrent vomiting, abdominal pain, polyuria, polydipsia, and dehydration are the most often noted clinical symptoms of vitamin D toxicity (VDT; also called vitamin D intoxication or hypervitaminosis D).

How often should I take 5000 IU of vitamin D3?

In patients with vitamin D levels less than 20 ng/mL, start with 50,000 IUs of vitamin D3 once a week for 6 to 8 weeks. After that, a dose of 800 to 2000 IU per day should be taken to maintain vitamin D levels above 30 ng/mL.

How common is vitamin D toxicity?

Although vitamin D toxicity is a very rare condition, recent increases in supplement use may lead to an increase in reported cases. A daily intake ranging from 40,000–100,000 IU (1,000–2,500 mcg), for 1 to several months, has been shown to cause toxicity in humans ( 15 , 19 , 20 , 21 , 22 ).

Is it OK to take 1000 IU vitamin D3 daily?

However, 1,000 to 2,000 IU per day of vitamin D from a supplement is generally safe, should help people achieve an adequate blood level of vitamin D, and may have additional health benefits.

What is the difference between vitamin D and vitamin D3?

There are two possible forms of vitamin D in the human body: vitamin D2 and vitamin D3. Both D2 and D3 are simply called “vitamin D,” so there's no meaningful difference between vitamin D3 and just vitamin D.

Can I take 4000 IU vitamin D3?

The recommended dietary allowance for vitamin D is 600 IU/d for adults 70 years or younger and 800 IU/d for those older than 70 years. The tolerable upper limit is 4000 IU/d; beyond this level risk of toxic effects increases.

How do you flush vitamin D out of your system?

But how do you flush vitamin D out of your system – and can you even do that? Yes, by ensuring you consume plenty of water. This will encourage urination, allowing your body to shed the excess vitamin D and calcium more quickly. Prescription diuretics like furosemide can also be helpful.

What vitamins can be hard on the kidneys?

You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K. These vitamins are more likely to build up in your body and can cause harm if you have too much. Over time, they can cause dizziness, nausea, and even death.

Can vitamin D make your joints hurt?

Another study predicted that adults with a vitamin D deficiency who are older than 50 are more likely to develop pain in their hip and knee joints. The study also noted that the pain is more likely to get worse if the deficiency isn't treated.

Can vitamin D3 cause calcification of arteries?

Experimental studies have shown that excessive vitamin D activities can induce vascular calcification, and such vascular pathology can be reversed by reducing vitamin D activities. The human relevance of these experimental studies is not clear, as vitamin D toxicity is relatively rare in the general population.

Will vitamin D3 raise blood pressure?

Conclusion: Oral vitamin D ₃ has no significant effect on blood pressure in people with vitamin D deficiency. It reduces systolic blood pressure in people with vitamin D deficiency that was older than 50 years old or obese.

What drugs should not be taken with vitamin D?

Is it better to take vitamin D every day or once a week?

Conclusion. Daily vitamin D was more effective than weekly, and monthly administration was the least effective.

Is 50000 units of vitamin D alot?

Conclusions: Vitamin D3 therapy (50,000-100,000 IU/week) was safe and effective when given for 12 months to reverse statin intolerance in patients with vitamin D deficiency. Serum vitamin D rarely exceeded 100 ng/mL, never reached toxic levels, and there were no significant change in serum calcium or eGFR.

How much vitamin D3 should a 50 year old woman take?

A: The upper tolerable limit is 4,000 international units (IU) daily, and the recommended amount for women 14 to 70 is 600 IU per day. Women 71 and older should aim for 800 IU per day.

Why do doctors prescribe vitamin D2 instead of D3?

You may wonder why doctors prescribe vitamin D2 instead of D3, if vitamin D3 appears to be more potent than vitamin D2. The vitamin D prescription you get from your doctor is typically for 50,000 units of vitamin D2. Vitamin D2 is indicated to treat calcium disorders and parathyroid disorders.