Is the Johnson and Johnson vaccine mRNA?

The Moderna and Pfizer vaccines use mRNA technology, and the Johnson & Johnson vaccine uses the more traditional virus-based technology. mRNA is essentially a little piece of code that the vaccine delivers to your cells.
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Are mRNA vaccines preferred over Johnson and Johnson vaccine for COVID-19?


The mRNA vaccines are preferred over Johnson & Johnson's Janssen COVID-19 vaccine (a viral vector vaccine) in most circumstances. Although mRNA vaccines are preferred, the J&J/Janssen COVID-19 vaccine may be considered in some situations.

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Is it safe to take the Johnson and Johnson COVID-19 vaccine?


For many people, the benefits of the Johnson & Johnson vaccine outweigh the risks. It's effective at preventing severe illness, hospitalization, and death from COVID-19, and it's the only single-dose option available. However, you'll still need to get a booster shot 2 months later.

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How does the Johnson and Johnson COVID-19 vaccine work?


The J&J/Janssen COVID-19 vaccine also contains a piece of a modified virus that is not the virus that causes COVID-19. This modified virus is called the vector virus. The vector virus cannot reproduce itself, so it is harmless. This vector virus gives instructions to cells in the body to create an immune response.

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Is the Johnson and Johnson COVID-19 vaccine a viral vector vaccine?


The Johnson & Johnson Janssen vaccine, a viral vector vaccine, is among the COVID-19 vaccines authorized for emergency use in the United States.

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How the Johnson



What are the ingredients in the Janssen COVID-19 vaccine?

The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl-β-cyclodextrin (HBCD), polysorbate-80, sodium chloride.
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Is there a live virus in the mRNA COVID-19 vaccines?

The mRNA vaccines do not contain any live virus. Instead, they work by teaching our cells to make a harmless piece of a “spike protein,” which is found on the surface of the virus that causes COVID-19. After making the protein piece, cells display it on their surface.
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Does the Single-shot Janssen/Johnson & Johnson COVID-19 vaccine produce a strong immune response?

•The immune response to the single-shot Janssen/Johnson & Johnson COVID-19 vaccine remained robust against variants of SARS-CoV-2.
•Although the vaccine produced fewer neutralizing antibodies against the variants than the original virus, the overall immune response suggests strong protection.

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Are egg products used in COVID-19 vaccines?

The COVID-19 vaccines currently authorized by the FDA are not manufactured using egg products or egg culture. See COVID-19 vaccines for more information.
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What is the Novavax COVID-19 vaccine?


Novavax's offering is a protein subunit vaccine, similar to those used to protect against flu, and for routine childhood immunisations against pertussis (whooping cough), and meningococcal infection.

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Who is at higher risk of getting blood clots from the Johnson & Johnson COVID-19 vaccine?


They are also more likely to occur in women who are pregnant or on oral contraceptives, or in people who have hereditary disorders that predispose them to blood clotting. As mentioned above, the clotting condition associated with the J&J vaccine is called thrombosis with thrombocytopenia (TTS).

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What are the common side effects of the Johnson and Johnson COVID-19 vaccine?


Side effects that have been reported with the Janssen COVID-19 Vaccine include: Injection site reactions: pain, redness of the skin, and swelling. General side effects: headache, feeling very tired, muscle aches, nausea, fever. Swollen lymph nodes.

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Is it safe to take the Moderna, Pfizer-BioNTech, or J&J COVID-19 vaccine during pregnancy?

No safety concerns were found in animal studies: Studies in animals receiving a Moderna, Pfizer-BioNTech, or Johnson & Johnson (J&J)/Janssen COVID-19 vaccine before or during pregnancy found no safety concerns in pregnant animals or their babies.
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Why did the CDC among other reasons recommend the mRNA COVID-19 vaccines over the Johnson & Johnson vaccine?


In December, the CDC recommended a preference for the two mRNA vaccines over J&J in response to concerns that had been building over a small, but growing number of cases of a rare, but serious clotting disorder in people who'd gotten the shot.

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What is the best vaccine for COVID-19?


In most situations, mRNA COVID-19 vaccines (Pfizer-BioNTech or Moderna) are preferred over the J&J/Janssen COVID-19 vaccine for primary and booster vaccination due to the risk of serious adverse events.

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Are severe reactions to mRNA COVID-19 vaccines common?


We found that reported reactions to mRNA vaccination were mostly mild in severity and transient in duration, and most reports were non-serious. Reactions and health impacts were reported more frequently in female than in male recipients, and in individuals younger than 65 years than in older individuals.

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Does Johnson and Johnson COVID-19 vaccine have egg by product in it?


No food proteins like eggs or egg products, gluten, peanuts, tree nuts, nut products, or any nut byproducts (COVID-19 vaccines are not manufactured in facilities that produce food products).

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What is the most important ingredient in both Pfizer and Moderna COVID-19 vaccines?


The most important ingredient in both the Pfizer and Moderna vaccines is mRNA. The mRNA tells your cells how to make a protein from the coronavirus. Once your body knows how to make the protein, it can recognize COVID-19 and fight it. Learn more about how mRNA vaccines work.

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Can you get the mRNA COVID-19 vaccine if you are allergic to the ingredient in the vaccine?

If you are allergic to an ingredient in a COVID-19 vaccine
If you have had a severe allergic reaction or an immediate allergic reaction—even if it was not severe—to any ingredient in an mRNA COVID-19 vaccine, you should not get either of the currently available mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna).

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How does the COVID-19 vaccine boost your immune system?

Vaccines work by stimulating your immune system to produce antibodies, exactly like it would if you were exposed to the disease. After getting vaccinated, you develop immunity to that disease, without having to get the disease first.
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How effective was single-shot of the Johnson and Johnson COVID-19 vaccine?


The Johnson & Johnson COVID-19 vaccine demonstrated a profile that showed durability of effectiveness up to 6 months for hospitalizations and ICU admissions across the study period, with a modest increase in breakthrough infections starting in month 4.

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Does the COVID-19 vaccine give you immunity?


Getting fully vaccinated also gives you months of immunity -- without making you sick from the coronavirus. The vaccines are safe and effective. Even though they become less effective over time, they can still help protect you from getting severely ill from a breakthrough infection.

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Can the Moderna COVID-19 vaccine cause allergic reactions?

There is a remote chance that the Moderna COVID-19 Vaccine could cause a severe allergic
reaction. A severe allergic reaction would usually occur within a few minutes to one hour after
getting a dose of the Moderna COVID-19 Vaccine. For this reason, your vaccination provider
may ask you to stay at the place where you received your vaccine for monitoring after
vaccination. Signs of a severe allergic reaction can include:
• Difficulty breathing
• Swelling of your face and throat
• A fast heartbeat
• A bad rash all over your body
• Dizziness and weakness

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Are there any safety concerns concerning mRNA technology of the Pfizer-BioNTech COVID-19 Vaccine?

FDA does not have specific safety concerns with a vaccine that utilizes this technology.

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Can you get the COVID-19 vaccine if you have an allergic reaction?


If you have had an immediate allergic reaction (a reaction that started within 4 hours) to any vaccine other than a COVID-19 vaccine or any injectable therapy, you may still be able to get a COVID-19 vaccine. However, your doctor may refer you to an allergy and immunology specialist for additional care or advice.

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