Is Plaquenil a high risk medication?

Hydroxychloroquine treatment appears to have no increased risk in the short term among patients with rheumatoid arthritis, but in the long term it appears to be associated with excess cardiovascular mortality.
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What medications are considered high risk medications?

High risk medications
  • A – Antimicrobials.
  • P – Potassium and other electrolytes, psychotropic medications.
  • I – Insulin.
  • N – Narcotics, opioids and sedatives.
  • C – Chemotherapeutic agents.
  • H – Heparin and other anticoagulants.
  • S – Safer systems (e.g. safe administration of liquid medications using oral syringes)
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What is the most serious side effect of hydroxychloroquine sulfate Plaquenil )?

Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/irregular heartbeat, seizures. This medication may cause serious eye/vision problems.
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Does taking hydroxychloroquine make you immunocompromised?

Please note that hydroxychloroquine (Plaquenil) does NOT suppress your immune system and does not increase any risk for a more serious illness from COVID-19.
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What is the downside of taking hydroxychloroquine?

muscle weakness. unusual bleeding or bruising. bleaching or loss of hair. mood or mental changes.
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07 High Risk Medication



Should I stop taking immunosuppressants if I have Covid?

Q: Should I stop my medication as a precaution? You should continue taking your medicines, including steroids, unless instructed otherwise by your clinician. If you stop taking your medicine, it could cause a flare-up of your condition which could increase your risk of complications if you get coronavirus.
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What is the safest drug for rheumatoid arthritis?

Methotrexate is widely regarded as one of the safest of all arthritis drugs, though it carries some potential downsides. Gastrointestinal symptoms such as nausea and vomiting are its most frequent side effects.
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What is the difference between Plaquenil and hydroxychloroquine?

Hydroxychloroquine is used in the treatment of arthritis to help relieve inflammation, swelling, stiffness, and joint pain and also to help control the symptoms of lupus erythematosus (lupus; SLE). A common brand name for hydroxychloroquine is Plaquenil®.
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What can hydroxychloroquine do to your heart?

Hydroxychloroquine and chloroquine can cause abnormal heart rhythms such as QT interval prolongation and a dangerously rapid heart rate called ventricular tachycardia.
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What are the top 5 high-alert medications?

The top five high-alert medications identified by the ISMP study are insulin; opiates and narcotics; injectable potassium chloride (or phosphate) concentrate (See Sentinel Event Alert, Issue 1); intravenous anticoagulants (heparin); and sodium chloride solutions above 0.9 percent.
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Which medications fall within the high-alert category?

Classes/categories of high-alert medications
  • adrenergic agonists, IV (e.g., EPINEPHrine, phenylephrine, norepinephrine)
  • adrenergic antagonists, IV (e.g., propranolol, metoprolol, labetalol)
  • anesthetic agents, general, inhaled and IV (e.g., propofol, ketamine)
  • antiarrhythmics, IV (e.g., lidocaine, amiodarone)
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Which of the following is considered a high-alert medication?

*All forms of insulin, subcutaneous and IV, are considered a class of high-alert medications. Insulin U-500 has been singled out for special emphasis to bring attention to the need for distinct strategies to prevent the types of errors that occur with this concentrated form of insulin.
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How long does Plaquenil stay in your system after stopping it?

The half-life of Plaquenil is about 40 to 50 days. In other words, it takes about 40 to 50 days for your body to get rid of half of a dose of Plaquenil. It typically takes about five half-lives for a drug to leave your body completely. This means that Plaquenil stays in your system for about 200 to 250 days.
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How common is blindness from hydroxychloroquine?

Hydroxychloroquine-related eye problems were once considered rare, but better detection methods now show that they occur in about 7 percent of patients.
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How often do you need eye exams on Plaquenil?

Patients starting treatment with Plaquenil should have a baseline eye examination within the first year of taking this medication and then regular screenings thereafter; every six months or yearly as advised by your eye doctor.
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What can be taken instead of Plaquenil?

Types of antimalarials

Hydroxychloroquine (Plaquenil) is the most common antimalarial for lupus. If you can't take hydroxychloroquine, your doctor may recommend chloroquine (Aralen®).
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What are the long term side effects of Plaquenil?

Long-term use and high doses of hydroxychloroquine are risk factors for the development of cardiomyopathy. Cardiac failure, conduction disorders (including QT prolongation and Torsades de Pointes) and sudden cardiac death are consequences of the cardiomyopathy.
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Can Plaquenil cause high blood pressure?

Hydroxychloroquine can cause a serious heart problem.

Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
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Is Plaquenil better than methotrexate?

Methotrexate has an average rating of 6.6 out of 10 from a total of 264 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 24% reported a negative effect. Plaquenil has an average rating of 6.6 out of 10 from a total of 112 ratings on Drugs.com.
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Can you have the Covid vaccine if you have rheumatoid arthritis?

Don't Worry About Minor Side Effects. Studies have provided reassurance about side effects of the COVID-19 vaccines for people with RA. According to a report published in JAMA in February 2022, data from more than 5,000 people in 30 countries with rheumatic disease has indicated minimal problems after getting the shots ...
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Is hydroxychloroquine safe to take for rheumatoid arthritis?

Hydroxychloroquine. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis.
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Are people with autoimmune diseases immunocompromised?

The term “immunocompromised” typically implies that your immune system is weaker than it should be. People with autoimmune disease aren't typically considered immunocompromised, unless they take certain medications that slow down their immune system.
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Is rheumatoid arthritis a risk for Covid?

If you have rheumatoid arthritis (RA), you're more likely to get certain infections. That means you may have a higher chance of getting COVID-19. If you do get sick, your symptoms could be more serious than someone who doesn't have RA. Some medicines you take might also make infections more likely.
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Do immunosuppressants make you more susceptible to Covid?

They found that the COVID-19 patients who were immunosuppressed prior to their COVID-19 hospitalization did not, on average, have worse COVID-19 outcomes—such as longer length of stay in the hospital, death in hospital, or use of a ventilator—compared to their counterparts who were not immunosuppressed.
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