Is melanoma in situ serious?

In situ melanomas don't spread to other parts of the body or cause death, but if the tumor has an opportunity to grow even one millimeter deep into the skin, it can lead to more involved treatment and greater danger. If left untreated, it can metastasize and even become life-threatening.
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How long does melanoma in situ take to spread?

The lesion can grow slowly for 5 to 15 years in the in situ form before becoming invasive. The exact percentage of lentigo maligna lesions that progress to invasive lentigo maligna melanoma is unknown but is estimated to be less than 30% to 50%.
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Can melanoma stay in situ forever?

Prognosis: Stage 0 melanoma, or melanoma in situ, is highly curable. There is very little risk for recurrence or metastasis. The 5-year survival rate as of 2018 for local melanoma, including Stage 0, is 98.4%.
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Is melanoma in situ really melanoma?

Melanoma in situ is also called stage 0 melanoma. It means there are cancer cells in the top layer of skin (the epidermis). The melanoma cells are all contained in the area in which they started to develop and have not grown into deeper layers of the skin. Some doctors call in situ cancers pre cancer.
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How is in situ melanoma treated?

Stage 0 melanoma (melanoma in situ) has not grown deeper than the top layer of the skin (the epidermis). It is usually treated by surgery (wide excision) to remove the melanoma and a small margin of normal skin around it. The removed sample is then sent to a lab to be looked at with a microscope.
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The 4 Stages of Melanoma: The Deadliest Form of Skin Cancer - Mayo Clinic



How quickly should melanoma in situ be removed?

Hypothesis-based, informal guidelines recommend treatment within 4–6 weeks. In this study, median surgical intervals varied significantly between clinics and departments, but nearly all were within a 6-week frame. Key words: melanoma, surgical interval, treatment time, melanoma survival, time factors.
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What does it mean to have melanoma in situ?

Listen to pronunciation. (MEH-luh-NOH-muh in SY-too) Abnormal melanocytes (cells that make melanin, the pigment that gives skin its natural color) are found in the epidermis (outer layer of the skin). These abnormal melanocytes may become cancer and spread into nearby normal tissue.
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Should I be worried about in situ melanoma?

In situ melanomas don't spread to other parts of the body or cause death, but if the tumor has an opportunity to grow even one millimeter deep into the skin, it can lead to more involved treatment and greater danger. If left untreated, it can metastasize and even become life-threatening.
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Is Stage 1 melanoma serious?

Stage 1 is considered a 'thin melanoma'. If your melanoma is caught before it is too thick the prognosis is very good. Nearly 19 in 20 people who have a stage 1 melanoma are alive at least five years after being diagnosed. Stage 1 is the least serious type of melanoma.
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How often does melanoma in situ recur?

Location of primary melanoma in situ. The average histological excision margin was 3.7 mm (range, 0.2–14 mm). The rate of recurrence was 2.2% (9/410), with a mean time to recurrence of 29.6 months (range, 8–47 months). This is comparable to recent international studies (Table 1).
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How thick is melanoma in situ?

This stage is also known as melanoma in situ. The tumor is more than 1 mm thick (T2b or T3) and may be thicker than 4 mm (T4). It might or might not be ulcerated. The cancer has not spread to nearby lymph nodes (N0) or to distant parts of the body (M0).
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Can you live 20 years with melanoma?

Survival for all stages of melanoma

Generally for people with melanoma in England: almost all people (almost 100%) will survive their melanoma for 1 year or more after they are diagnosed. around 90 out of every 100 people (around 90%) will survive their melanoma for 5 years or more after diagnosis.
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What does Stage 1 melanoma look like?

Stage IA Melanoma: The melanoma tumor is less than 1.0 millimeter thick (less than the size of a sharpened pencil point) with or without ulceration (broken skin) when viewed under the microscope. Stage IB Melanoma: The melanoma tumor is more than 1.0 millimeter and less than 2.0 millimeters thick without ulceration.
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Is early evolving melanoma in situ reportable?

Early/evolving melanoma in situ (8720/2) and early/evolving melanoma invasive (8720/3) are reportable for cases diagnosed 1/1/2021 and later.
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Can you survive melanoma if caught early?

There are five stages of melanoma ranging from stage 0 to stage 4. Survival rates are just estimates and don't ultimately determine an individual's specific prognosis. Early diagnosis greatly increases survival rates.
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Is melanoma a death sentence?

Metastatic melanoma was once almost a death sentence, with a median survival of less than a year. Now, some patients are living for years, with a few out at more than 10 years.
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Can Stage 1 melanoma make you tired?

Extreme fatigue that doesn't get better with rest can be an early sign of cancer. Cancer uses your body's nutrients to grow and advance, so those nutrients are no longer replenishing your body. This “nutrient theft” can make you feel extremely tired.
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What are the early warning signs of melanoma?

The most important warning sign of melanoma is a new spot on the skin or a spot that is changing in size, shape, or color. Another important sign is a spot that looks different from all of the other spots on your skin (known as the ugly duckling sign).
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Does Stage 0 melanoma spread?

In Stage 0 melanoma, there is no evidence the cancer has spread to the lymph nodes or to distant sites (metastasis). Stage 0 is local melanoma, meaning it has not spread beyond the primary tumor.
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How common is a melanoma in situ UK?

About 7,000 people in the UK are diagnosed with melanoma each year. It is more common in women than men. It is a rare cancer in children, but it is the second most common cancer in people aged 15 to 34.
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What are the chances of stage 1 melanoma returning?

Conclusions and Relevance These findings suggest that 13.4% of patients with a high-risk primary melanoma will experience disease recurrence within 2 years. Head or neck location of initial tumor, SLNB positivity, and signs of rapid tumor growth may be associated with primary melanoma recurrence.
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Can melanoma spread after removed?

After you finish treatment, your dermatologist (or oncologist) will still want to see you regularly. Melanoma can return or spread after treatment. If this happens, it's most likely to occur within the first 5 years.
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Which is worse melanoma or carcinoma?

While it is less common than basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), melanoma is more dangerous because of its ability to spread to other organs more rapidly if it is not treated at an early stage. Learn more about melanoma types, risk factors, causes, warning signs and treatment.
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Can melanoma be completely removed?

Treatment for early-stage melanomas usually includes surgery to remove the melanoma. A very thin melanoma may be removed entirely during the biopsy and require no further treatment. Otherwise, your surgeon will remove the cancer as well as a border of normal skin and a layer of tissue beneath the skin.
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