Is Klinefelter's a disability?

Most males with the 47,XXY karyotype have normal intelligence. Intellectual disability occurs in males with Klinefelter syndrome variants, who have a higher number of X chromosomes. About 70% of patients have minor developmental and learning disabilities.

How serious is Klinefelter syndrome?

Klinefelter syndrome is not necessarily anything serious, but treatment can help reduce some of the symptoms if necessary. In many cases, it's only detected if a man with the condition undergoes fertility tests.

Is Klinefelter mental retardation?

Abstract. Klinefelter syndrome (KS) has not typically been associated with mental retardation (MR), however, in recent years a growing body of evidence suggested that KS boys often experience language deficits and academic difficulties.

Is Klinefelter syndrome a mental disorder?

Researchers of a large cohort study found that Klinefelter syndrome was associated with diagnoses of psychoses, neuroses and personality disorders.

What limitations does a person with Klinefelter syndrome have?

When a Child or Teen has Klinefelter Syndrome - Dr. Mark Daniels

Can you have a normal life with Klinefelter?

The XXY condition that causes Klinefelter syndrome can't be changed, but medical treatment and working with therapists can help a boy's development and lessen the condition's effects. Even without treatment, most boys with Klinefelter syndrome grow up to live productive, healthy lives.

Can people with Klinefelter syndrome get an erection?

Klinefelter's syndrome is a condition that has a variable presentation. Despite having a higher likelihood of reduced sexual desire, patients may have normal erectile function comparable to age-matched individuals.

Is Klinefelter syndrome autism?

In about 10-25% of cases, it is associated with known medical conditions. Population-based studies of autism have found that Klinefelter's syndrome (KS), a common chromosome abnormality, is sometimes associated with autism.

Why are Klinefelter males tall?

From early school age, boys with Klinefelter's syndrome tend to be taller (increased leg length) because testosterone normally stops boys growing after puberty. This increase in height is maintained throughout life. Patients with Klinefelter's syndrome may have reduced coordination compared with other boys.

Is Klinefelter syndrome considered intersex?

Other intersex conditions, including the last four conditions listed above—complete androgen insensitivity, Klinefelter syndrome, Turner syndrome, and vaginal agenesis—usually do not result in ambigu- ous genitals and may not be recognized at birth.

What is the quality of life with Klinefelter syndrome?

Quality of life is significantly impaired in men with Klinefelter Syndrome, most likely due to discrimination and the presence of somatic and mental health problems. A multidisciplinary approach of healthcare providers might help to provide adequate counselling and treatment to improve quality of life.

Does Klinefelter syndrome affect teeth?

Consequently, males affected by KS have larger teeth than males with a normal chromosomal complement (19, 32, 36, 44, 47-49). The importance of the X chromosome to tooth size is directly related to the number of extra X chromosomes, and its effect on general growth patterns and enamel thickness (50).

Can a man with Klinefelter syndrome have babies naturally?

It is possible that an XXY male could get a woman pregnant naturally. Although sperm are found in more than 50% of men with KS³, low sperm production could make conception very difficult.

Can you be short with Klinefelter syndrome?

Although one of the most characteristic features of Klinefelter syndrome is tall stature, some uncommon variants are associated with short stature (49 XXXXY, isochromosome Xq) [3–5]. To the knowledge, there are few reported cases of Klinefelter syndrome and short stature secondary to growth hormone deficiency [1, 4].

What is the survival rate of Klinefelter syndrome?

The mortality among KS men was 40% higher than that among population controls (hazard ratio, 1.40; 95% CI, 1.13–1.74; P = 0.002). The median survival age among KS subjects was 71.4 yr compared with 73.5 yr in controls, a difference of 2.1 yr (95% CI, 0.3–3.9; Fig. 1).

Are all Klinefelter's infertile?

Between 95% and 99% of XXY men are infertile because they do not produce enough sperm to fertilize an egg naturally. But, sperm are found in more than 50% of men with KS.

What is interesting about Klinefelter syndrome?

Klinefelter syndrome results when a boy is born with at least 1 extra X chromosome. This is written as XXY. Klinefelter syndrome occurs in about 1 out of 500 to 1,000 baby boys. Women who get pregnant after age 35 are slightly more likely to have a boy with this syndrome than younger women.

Can people with Klinefelter syndrome grow beard?

Some males with Klinefelter syndrome have the extra X chromosome only in some of their cells (mosaic Klinefelter syndrome). Man suffering from Klinefelter syndrome has significantly lower level of testosterone, which mai lead to muscle and beard loss.

What is Mosaic Klinefelter syndrome?

Klinefelter syndrome (KS) mosaicism 46,XX/47,XXY is an extremely rare disorder of sex development characterized by the presence of both ovarian and testicular tissues in the same individual.

What are the chances of having a child with Klinefelter syndrome?

Klinefelter syndrome is one of the most common chromosome conditions in newborns. It affects between 1 in 500 and 1 in 1,000 newborn males. Variants of the disease with three, four, or more extra X chromosomes are less common. These variants affect 1 in 50,000 or fewer newborns.

What does an extra Y chromosome do?

The extra X and/or Y chromosome can affect physical, developmental, behavioral, and cognitive functioning. Common physical features may include tall stature, lack of secondary pubertal development, small testes (hypogonadism), delayed pubertal development, and breast development (gynecomastia) in late puberty.

Can Klinefelter masturbate?

Unexpectedly, he described markedly increased libido characterized by uncontrollable urges to masturbate and the need for frequent heterosexual encounters.

Does Klinefelter syndrome cause gender dysphoria?

Abstract. Introduction: An increased risk of autistic traits in Klinefelter syndrome (KS) has been reported. In addition, some studies have shown an increased incidence of gender dysphoria (GD) and paraphilia in autism spectrum disorder.

How is Klinefelter syndrome diagnosed?

Blood or urine samples can reveal abnormal hormone levels that are a sign of Klinefelter syndrome. Chromosome analysis. Also called karyotype analysis, this test is used to confirm a diagnosis of Klinefelter syndrome. A blood sample is sent to the lab to check the shape and number of chromosomes.

Is Klinefelter's dominant or recessive?

Klinefelter syndrome with fabry disease--a case of nondisjunction of the X-chromosome with sex-linked recessive mutation.