Is hairy cell leukemia a form of non Hodgkin's lymphoma?

Hairy cell leukaemia variant
Despite its name, it is classed as a form of non-Hodgkin lymphoma. It is very rare. Like classical hairy cell leukaemia, the abnormal cells in HCL-V look hairy under a microscope.
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What type of cancer is hairy cell leukemia?

Hairy cell leukemia is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). Hairy cell leukemia is a cancer of the blood and bone marrow. This rare type of leukemia gets worse slowly or does not get worse at all.
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Is leukemia and non Hodgkin's lymphoma the same thing?

Leukemia and lymphoma are both forms of blood cancer, but they affect the body in different ways. The main difference is that leukemia affects the blood and bone marrow, while lymphomas mainly affect the lymph nodes.
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What is another name for hairy cell leukemia?

Hairy cell leukemia (HCL) was originally described as histiocytic leukemia, malignant reticulosis, or lymphoid myelofibrosis in publications dating back to the 1920s.
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Is hairy cell a leukemia or lymphoma?

Hairy cell leukemia is a rare, slow-growing cancer of the blood in which your bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. These excess B cells are abnormal and look "hairy" under a microscope.
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Hairy cell leukemia



What is the life expectancy of someone with hairy cell leukemia?

Generally for people with hairy cell leukaemia: around 95 out of every 100 (around 95%) will survive their leukaemia for 5 years or more after they are diagnosed.
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What is a common finding in patients with hairy cell leukemia?

Splenomegaly is the most common physical finding in hairy cell leukemia. It is present in virtually every patient with the disease and it is massive in more than 80% of patients. Hepatomegaly with mild liver function abnormalities is found in 20% of cases, and lymphadenopathy is found in 10%.
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How serious is hairy cell leukemia?

There is an unexplained larger number of men than women afflicted with this leukemia. Hairy cell leukemia is treatable, but not curable. While the cause is not known, the treatment is usually very effective in helping patients lead a normal life.
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Is hairy cell leukemia an autoimmune disease?

Background. Case reports suggest that hairy cell leukemia (HCL) may be associated with autoimmune conditions, however no systematic investigations in this area have been undertaken.
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What is the best treatment for hairy cell leukemia?

Chemotherapy. Doctors consider chemotherapy drugs the first line of treatment for hairy cell leukemia. A great majority of people will experience complete or partial remission through the use of chemotherapy.
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What's worse leukemia or lymphoma?

Which is more aggressive: leukemia or lymphoma? The survival rate for lymphoma is higher than leukemia. According to the Leukemia and Lymphoma Society, the 5-year survival rate of all leukemias combined is 65.8 percent.
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Can non-Hodgkin's lymphoma lead to leukemia?

Compared to individuals in the general population, patients with non-Hodgkin's lymphoma are at increased risk of developing a second cancer, particularly leukemia, lung, and skin cancers.
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Which is worse Non Hodgkins or Hodgkins lymphoma?

The prognosis of Hodgkin's lymphoma is also better than that of non-Hodgkin's lymphoma since non-Hodgkin's lymphoma is often diagnosed at a more advanced stage. Both forms of blood cancer are treatable when caught early, however.
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How long is chemo for hairy cell leukemia?

Pentostatin. Pentostatin given intravenously every other week for 3 to 6 months produces a 50% to 76% complete response rate and an 80% to 87% overall response rate.
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Is hairy cell leukemia inherited?

HCL is more common in men than in women. There is no clear evidence that HCL runs in families or is caused by specific environmental factors. The disease is called hairy cell leukemia because the leukemia cells have long thin projections that look like hairs.
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Is hairy cell leukemia acute or chronic?

HCL-V and classic hairy cell leukaemia are both chronic leukaemias. They develop slowly from cells called B lymphocytes.
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What are the 4 main types of leukemia?

There are 4 main types of leukemia, based on whether they are acute or chronic, and myeloid or lymphocytic:
  • Acute myeloid (or myelogenous) leukemia (AML)
  • Chronic myeloid (or myelogenous) leukemia (CML)
  • Acute lymphocytic (or lymphoblastic) leukemia (ALL)
  • Chronic lymphocytic leukemia (CLL)
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What are the side effects of cladribine?

Cladribine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • nausea.
  • vomiting.
  • diarrhea.
  • stomach pain.
  • constipation.
  • loss of appetite.
  • skin rash.
  • headache.
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Can Roundup cause hairy cell leukemia?

Glyphosate, the main active ingredient in weed killers such as Roundup and Honcho, has been found by the International Agency for Research on Cancer to be a "probable carcinogen," mostly associated with cancers of the lymphatic system and blood. One of the rarest forms of such diseases is hairy cell leukemia (HCL).
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When was hairy cell leukemia discovered?

Discovered in 1958 by Ohio State University cancer researcher Bertha Bouroncle, MD, hairy cell leukemia, or HCL, is a rare form of cancer in the blood and bone marrow that affects white blood cells.
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Which is more treatable Hodgkins or non-Hodgkin's?

Hodgkin's lymphoma is one of the most curable cancers. It typically has a better outlook than non-Hodgkin's lymphoma.
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Which has better survival rate Hodgkin's or non-Hodgkin lymphoma?

More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. About 70 percent of patients diagnosed with non-Hodgkin lymphoma survive five years or more. There are six varieties of Hodgkin lymphoma.
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Can leukemia turn into lymphoma?

Leukemia cells usually collect in the lymph nodes, spleen and liver. The buildup of leukemia cells in these organs affects them so they don't work normally. In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma.
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How many types of non-Hodgkin's lymphoma are there?

Lymphomas develop from white blood cells called lymphocytes. There are two types of lymphocyte: B-cell lymphocytes - lymphoma that develops from an abnormal B-cell lymphocyte is called a B-cell lymphoma. T-cell lymphocytes - lymphoma that develops from an abnormal T-cell lymphocyte is called a T-cell lymphoma.
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