Is 150 mg of clopidogrel too much?

Conclusion: As compared with the currently recommended 75-mg day(-1) maintenance dosage of clopidogrel, the 150-mg day(-1) dosage can reduce major adverse cardiac and/or cerebrovascular events but may increase the risk of minor bleeding.

What happens if I take clopidogrel twice a day?

The researchers found that patients undergoing angioplasty benefited from a double dose of Plavix, with their risk of heart attack, stroke or death reduced 14%, compared with patients who were given a standard dose. Moreover, the risk of clotting in the stent was cut 46% among those receiving the double dose.

Is clopidogrel a maintenance?

Conclusion: Our data suggest that a high maintenance dosage of clopidogrel (150 mg/day) is associated with a reduced risk of definite stent thrombosis and MACE compared with a maintenance dosage of 75 mg/day.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

What is the use of clopidogrel 75 mg?

Clopidogrel is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain.

clopidogrel 75 mg uses dosage and side effects

How long can you stay on clopidogrel?

Clopidogrel and low-dose aspirin

The key question for your doctor is whether the benefits outweigh the extra risk. This combination treatment is prescribed for a limited period of time, usually up to a maximum of 12 months.

Can you overdose on clopidogrel?

Clopidogrel, a second-generation thienopyridine, is used to inhibit platelet aggregation in a variety of disease states, primarily coronary artery disease (1). Despite its relatively wide spectrum of clinical applications, clopidogrel overdose have been very rarely reported in the literature (2).

When is the best time to take clopidogrel 75 mg?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel affect blood pressure?

You likely won't have blood pressure changes while you're taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.

What is the alternative to clopidogrel?

Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Can you take aspirin and clopidogrel together?

The combination of aspirin and clopidogrel is not recommended for routine use for any longer than 12 months after the acute phase of myocardial infarction (MI), unless there are other indications to continue dual antiplatelet therapy, and the combination is usually recommended for a shorter duration after an ST-segment ...

Which is best clopidogrel or aspirin?

Clopidogrel is another guideline‐recommended antiplatelet agent²¹ and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).

What is the difference between aspirin and clopidogrel?

Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).

Can you still have a stroke when taking clopidogrel?

If you stop taking clopidogrel, your blood will start clotting at the same rate as before you started taking it, usually within 5 days of stopping the medicine. This means you may be at increased risk of serious problems like heart attacks or strokes.

Can I drink coffee while taking clopidogrel?

These medications are used to slow blood clotting and include aspirin, clopidogrel (Plavix), ibuprofen (Advil, Motrin, and others), naproxen (Anaprox, Naprosyn, and others), enoxaparin (Lovenox), and more. Health experts advise caution when combining them with coffee, which can also slow blood clotting.

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.

How do you know if clopidogrel is working?

Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.

What foods should I avoid when taking clopidogrel?

Can clopidogrel cause anxiety?

headache, fever, weakness, feeling tired; little or no urination; a seizure; low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or.

Does clopidogrel affect sleep?

The organic nitrates (isosorbide) and the antiplatelet agents (acetylsalicylic acid, clopidogrel) are among the most prescribed drugs in cardiology and are not cited as causing insomnia or sleepiness.

Is clopidogrel 75 mg tablet a blood thinner?

Clopidogrel is an antiplatelet blood-thinning medicine that may help prevent future heart attacks, strokes, and other clot-related diseases in patients who have already had a heart attack, stroke, or have certain cardiovascular conditions.

Does clopidogrel affect blood sugar?

These results could indicate that clopidogrel has glucose lowering effect and the FSG level in placebo treated group significantly elevated after the same course of treatment.

What if I take too much Plavix?

If you take too much Plavix call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If Plavix is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur.

Can you drink alcohol if you are taking clopidogrel?

Can I drink alcohol while taking clopidogrel? ️ Yes (within the recommended limits). Alcohol doesn't affect clopidogrel itself, but just be aware that drinking alcohol can irritate your stomach lining. This could increase the risk of getting a bleeding in the stomach.

When Should clopidogrel be stopped?

While current guidelines recommend cessation of clopidogrel 5 to 7 days before an operative procedure, our data demonstrate that timing of clopidogrel cessation within 7 days of an operative procedure does not affect the prevalence of postoperative bleeding requiring transfusion or mortality.