How often does leukemia come back?

Overall, about 10 to 20 percent of people with ALL will have a relapse. This typically happens within 2 years of initial treatment. Adults with ALL are more likely (50 percent) to experience a relapse than children (10 percent).
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Can leukemia come back after being cured?

(When leukemia comes back after treatment, it is called a relapse or recurrence.) This is a very common concern in people who have had leukemia. For other people, the leukemia may not go away completely.
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What are the chances of ALL leukemia returning?

Despite an 85 to 90 percent cure rate after first treatment for children, adolescents and young adults with acute lymphoblastic leukemia (ALL), 10 to 15 percent of patients with pediatric ALL will experience relapse. ALL relapse can happen months or years following remission.
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When does leukemia usually relapse?

Relapse of ALL generally occurs within two years of initial treatment, although it may occur several months to years after the initial remission.
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Can you get leukemia a second time?

Relapse of leukemia may occur several months to years after the initial remission; however, the majority of relapses occur within 2 years of initial treatment. A variety of factors ultimately influence a patient's decision to receive treatment of cancer.
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Rate of Relapse for Acute Lymphoblastic Leukemia (ALL)



How do you know if leukemia has come back?

Your doctor will tell you that you've relapsed if the number of leukemia cells in your bone marrow has gone up and you have fewer healthy cells in your blood. AML can relapse if: The cancer didn't respond well to the first treatment you tried. Treatment didn't get rid of all the leukemia cells.
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Does leukemia usually come back?

Most often, acute myeloid leukemia (AML) will go into remission after the initial treatment. But sometimes it doesn't go away completely, or it comes back (relapses) after a period of remission.
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Can you survive a leukemia relapse?

Results. The median overall survival after relapse was 4.5 months (95% CI, 4–5 months) with a 5-year overall survival of 10% (95% CI, 8%–12%); 45% of patients receiving intensive second-line treatment achieved a second complete remission and 22% (95% CI, 14%–30%) of them remained disease free at 5 years.
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Can leukemia relapse after 5 years?

Relapse after 5 years of complete remission (CR) is uncommon in acute myeloid leukemia (AML). Among 2347 patients seen between 1980 and 2008, 1366 achieved CR; 942 relapsed. Eleven (1.16% of all relapses) relapsed after a CR of >5 years. The median age was 66 years (range, 37–79).
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What causes relapse in ALL leukemia?

Relapse happens because some leukaemia cells remain, often because they've become resistant to the drugs people are being treated with. If you do relapse you may be offered the opportunity to go on another clinical trial looking at new treatments for relapsed ALL.
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Can you be fully cured of leukemia?

As with other types of cancer, there's currently no cure for leukemia. People with leukemia sometimes experience remission, a state after diagnosis and treatment in which the cancer is no longer detected in the body. However, the cancer may recur due to cells that remain in your body.
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How long does leukemia remission last?

It depends on your treatment, age, and overall health. Remissions may last as much as 3-5 years after your first retreatment. Because future retreatments usually don't work as well as the first one, your next remissions may be shorter.
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Does leukemia shorten your life?

Today, the average five-year survival rate for all types of leukemia is 65.8%. That means about 69 of every 100 people with leukemia are likely to live at least five years after diagnosis. Many people will live much longer than five years. The survival rates are lowest for acute myeloid leukemia (AML).
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What is the deadliest leukemia?

Acute myeloid leukemia (AML) is the most fatal type of leukemia. The five-year survival rate (how many people will be alive five years after diagnosis) for AML is 29.5%.
...
Types of leukemia include:
  • B-cell prolymphocytic leukemia (B-PLL) (very rare)
  • T-cell prolymphocytic leukemia (T-PLL) (extremely rare)
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What happens when you relapse with leukemia?

You might experience chills, easy bleeding, unexplained weight loss, and fatigue. This happens because the cancer cells have started multiplying in your bone marrow again. If your ALL has relapsed, you'll usually need more chemotherapy and possibly additional treatments as well.
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Can leukemia be cured if caught early?

Leukemia is the cancer of the blood-forming tissues that includes bone marrow and lymphatic system. Adults and children are equally affected by Leukemia, which is seen as production of abnormal white blood cells by the bone marrow.
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Is leukemia permanent?

A remission may be temporary or permanent. This uncertainty causes many people to worry that the leukemia will come back. While many remissions are permanent, it is important to talk with your child's doctor about the possibility of the disease returning.
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Is leukemia a terminal?

Survival rate by age

Latest figures show that the 5-year survival rate for all subtypes of leukemia is 61.4 percent . A 5-year survival rate looks at how many people are still alive 5 years after their diagnosis. Leukemia is most common in people aged over 55, with the median age of diagnosis being 66.
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What is the survival rate of ALL leukemia?

The 5-year survival rate for people age 20 and older is 40%. The 5-year survival rate for people under age 20 is 89%. Recent advances in treatment have significantly lengthened the lives of people with ALL. However, survival rates depend on several factors, including biologic features of the disease and a person's age.
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Can you live 20 years with leukemia?

People in stages 0 to II may live for 5 to 20 years without treatment. CLL has a very high incidence rate in people older than 60 years. CLL affects men more than women. If the disease has affected the B cells, the person's life expectancy can range from 10 to 20 years.
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Can you live a full life with leukemia?

Chronic lymphocytic leukemia (CLL) can rarely be cured. Still, most people live with the disease for many years. Some people with CLL can live for years without treatment, but over time, most will need to be treated.
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Does having chemo shorten your lifespan?

During the 3 decades, the proportion of survivors treated with chemotherapy alone increased from 18% in 1970-1979 to 54% in 1990-1999, and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).
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Is there hope for leukemia patients?

When you hear the word leukemia, your mind automatically goes to the past, when there was little hope of survival. Today, things have changed for many leukemia patients. Leukemia, a type of blood cancer defined by too many white blood cells, is different for each patient.
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How successful is chemotherapy for leukemia?

The cure rates and survival outcomes for patients with ALL have improved over the past few decades. Today, nearly 90 percent of adults diagnosed with ALL achieve a complete remission, which means that leukemia cells can no longer be seen in the bone marrow with a microscope.
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