How much is an injection of XIAFLEX?

Pain, swelling and bruising can develop in the injection area. Xiaflex costs $3,300 an injection, so a full course of eight injections would cost about $26,000, in addition to a doctor's fee. Doctors already use less expensive drugs off-label to treat Peyronies, including injections of a generic blood pressure drug.

How much is the injection for Peyronie's disease?

In 2013, CCH injections became the first FDA-approved drug treatment for Peyronie's, indicated for men with palpable plaque and curvature of at least 30 degrees. The treatment costs around $4,000 per injection, with a standard therapeutic course involving eight total injections.

Are XIAFLEX injections covered by insurance?

The XIAFLEX Copay Assistance Program can cover up to $1200 of your out-of-pocket costs for each injection of XIAFLEX (collagenase clostridium histolyticum). How much you pay for XIAFLEX depends on your health benefits or insurance coverage.

What is the success rate of XIAFLEX?

Studies have shown 34% improvement in penile curvature in men who underwent treatment with Xiaflex injection compared to 18% improvement in men treated with saline injection.

How many XIAFLEX injections do I need?

No more than 3 injections, each 4 weeks apart, should be given in the same area. If you are using this medication to treat Peyronie's disease, the medication is injected into the plaque in the penis by your healthcare provider.

Collagenase injections (Xiaflex) for Peyronie's disease | UroChannel

Is there a pill to cure Peyronie's disease?

The U.S. Food and Drug Administration today approved a new use for Xiaflex (collagenase clostridium histolyticum) as the first FDA-approved medicine to treat men with bothersome curvature of the penis, a condition known as Peyronie's disease.

How painful are XIAFLEX injections?

Pain. Although Xiaflex is not uncomfortable to receive, some patients have significant pain for up to 48 hours after the injection, with rare patients having discomfort beyond this period. Verapamil is more painful to receive, likely due to the volume of fluid, but is not significantly painful thereafter.

Why was XIAFLEX discontinued?

Pfizer ditches Xiaflex after poor sales, but Peyronie's label could improve growth. Pfizer's decision to hand its European rights to the Dupuytren's contracture drug Xiaflex back to Auxilium Pharmaceuticals indicates a lack of confidence that uptake of the drug, a slow-burn so far, will accelerate.

What vitamins help with Peyronie's disease?

More recently, a 2014 study reported treatment outcomes of patients with PD using 50 mg sildenafil daily or 400 IU vitamin E for 3 months. After 12 weeks, both groups showed similar reduction in plaque volume and penile curvature that was statistically significant.

How often is XIAFLEX given?

Xiaflex is usually given in a treatment cycle of 1 to 3 injections given 4 weeks apart.

How do I pay my XIAFLEX injection?

Bill as 2 units OR 2 separate lines of 1 unit

If you have questions about XIAFLEX ^® coding, please contact Endo Advantage^™ at 1-877-XIAFLEX (1-877-942-3539) or the payor's Provider Service Representative. Application of finger splint should be used only when the procedure is performed in a physician's office.

How long does it take for XIAFLEX to work?

After the second injection of each treatment cycle, you should wait at least 4 weeks before having sex or other sexual activity. Only engage in sexual activity if any pain or swelling in your penis has gone away.

Is there a generic for XIAFLEX?

Xiaflex is available in a generic form as collagenase Clostridium histolyticum.

Can I fix Peyronie's disease myself?

Peyronie disease often happens in a mild form that heals on its own in 6 to 15 months. There is no cure for Peyronie disease.

How do you fix Peyronie's disease at home?

Does insurance cover Peyronie's disease?

Medicare and most insurance plans cover the procedure in most cases. Billing specialists in the physician's office can help confirm your coverage.

How do you break up Peyronie's scar tissue?

Your doctor might suggest injecting a drug into the penis to break up the scar tissue. Some doctors use a drug called verapamil. Studies show it can decrease the curve and pain in many men. Collagenase clostridium histolyticum (Xiaflex) is another injected drug for treating Peyronie's.

Is Cialis good for Peyronies?

Medications prescribed for erectile dysfunction (Viagra, Levitra, Cialis) are sometimes beneficial for patients in the early stages of Peyronie's disease.

Does vitamin D Help Peyronie's?

Transforming growth factor beta-1 (TGF-β1) plays a major role in the pathogenesis of Peyronie's disease (PD). Vitamin D modulates the profibrotic effects of TGF-β1, as shown in recent studies. Therefore, vitamin D deficiency might be a contributing factor in the pathogenesis of PD.

How do I get XIAFLEX?

XIAFLEX for the treatment of Peyronie's disease is only available through a restricted program called the XIAFLEX Risk Evaluation and Mitigation Strategy (REMS) Program. Hypersensitivity reactions, including anaphylaxis.

How long is XIAFLEX treatment?

Treatment with Xiaflex® is a 3-day process that includes the injection of the solution, finger extension, and fabrication of a night-time splint.

How long does it take to recover from XIAFLEX?

“It took me several weeks to recover from the incisions followed by thirty physical therapy sessions after each surgery. With Xiaflex, the recuperative process took only two weeks, and I was back to normal.”

Can you drive after XIAFLEX injection?

You will be able to drive yourself home after the appointment. You may use ice as needed for 15-20 minutes to reduce swelling. You may take Tylenol or Ibuprofen as needed for pain.

Where do you inject XIAFLEX?

The dose of XIAFLEX® is 0.58 mg per injection into a palpable cord with a contracture of a metacarpophalangeal (MP) joint or a proximal interphalangeal (PIP) joint.