How much CoQ10 should I take with statins?

For people taking statin medications, the typical dosage recommendation for CoQ10 is 30–200 mg per day ( 13 ).
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Do I need CoQ10 if I take a statin?

Every cell in the body needs coenzyme Q10 to help generate energy. When you take a statin medication to lower your cholesterol, it may lower the amount of coenzyme Q10 in your cells and in your bloodstream, too. That's because the mechanism in your body that makes cholesterol also makes coenzyme Q10.
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Can statins and CoQ10 be taken together?

For heart health

CoQ10 supplementation may also function as a natural aid in lowering cholesterol and improving heart health. While there aren't enough studies to confirm how well it works to do this, it may be possible to combine CoQ10 with statins for better results.
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What medications should not be taken with CoQ10?

What Other Drugs Interact with Coenzyme Q10?
  • atorvastatin.
  • fluvastatin.
  • glyburide.
  • insulin aspart.
  • insulin detemir.
  • insulin glargine.
  • insulin glulisine.
  • insulin lispro.
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Should you take CoQ10 at night?

CoQ10 is fat soluble, so it should be taken with a meal containing fat so your body can absorb it. Also, taking CoQ10 at night may help with the body's ability to use it.
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Does Coenzyme Q10 Supplementation Reduce Statin Side Effects?



Is 400 mg CoQ10 too much?

Typically, 90–200 mg of CoQ10 per day are recommended, though some conditions may require higher dosages of 300–600 mg. CoQ10 is a relatively well-tolerated and safe supplement that may benefit a wide variety of people looking for a natural way to boost health.
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How much CoQ10 should I take for high cholesterol?

There is no established ideal dose of CoQ10. Studies have used doses of CoQ10 ranging from 50 milligrams to 1,200 milligrams in adults, sometimes split into several doses over the course of a day. A typical daily dose is 100 milligrams to 200 milligrams.
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How much is too much CoQ10?

Standard daily doses of CoQ10 range from 60 milligrams (mg) to 500 mg. The highest recommended dose is 1,200 mg. However, clinical trials have used dosages as high as 3,000 mg per day. Different types of CoQ10 supplements may also require different dosages.
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What are the side effects of too much CoQ10?

CoQ10 supplements appear to be safe and to produce few side effects when taken as directed. Mild side effects might include digestive problems such as: Upper abdominal pain. Loss of appetite.
...
Other possible side effects may include:
  • Headaches and dizziness.
  • Insomnia.
  • Fatigue.
  • Skin itching or rashes.
  • Irritability or agitation.
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What are the symptoms of low CoQ10?

What are the symptoms of CoQ10 deficiency? Whilst everyone is different, people who have a deficiency in CoQ10 levels often experience physical fatigue and muscle weakness, even while undertaking relatively non-strenuous physical activities such as walking.
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What vitamins should not be taken with statins?

Niacin, vitamin B3, is a supplement and prescription medication that can interact with atorvastatin. The interaction can increase the chance of myopathy and rhabdomyolysis. The risk of an interaction is typically with higher doses of niacin (> 1 gram per day).
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What does Dr Oz say about CoQ10?

As such, we recommend anyone taking these medications should consider adding supplemental CoQ10 in the form of ubiquinol to their daily regimen. Double-blind clinic research studies report that supplementation with forms of CoQ10 can help significantly decrease blood pressure in people who have hypertension.
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Do doctors recommend CoQ10?

However, “there are currently doctors recommending CoQ10 supplements in addition to established treatments such as statins, as the supplements are generally recognized as safe, and potentially beneficial,” Peart says.
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Can you take vitamin D and statins together?

Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
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What supplements should you take with statins?

CoQ10 Supplements

Coenzyme Q10 (CoQ10), a nutrient produced by the body and used for cellular energy, is often touted as being vital if you're taking statin drugs to lower cholesterol.
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Can CoQ10 lower cholesterol?

The findings of current systematic review and meta-analysis showed that CoQ10 supplementation significantly improved lipid profiles by decreasing total cholesterol and increasing HDL-cholesterol levels, though did not affect triglycerides, LDL-cholesterol and Lp(a) levels in patients with CAD.
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Which is better for heart CoQ10 or fish oil?

Both fish oil and CoQ10 are best known for their heart-healthy benefits. Fish oil naturally regulates the level of inflammation in your body, and it may help fight high levels of inflammation that are linked to cardiovascular disease.
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What is the best brand of CoQ10 to take?

Summary of Recommendations
  • Best overall: Garden of Life Raw CoQ10.
  • Best budget pick: Kirkland Maximum Potency.
  • Best high dose: Puritan's Pride Q-Sorb 600mg.
  • Best vegan option: Garden of Life Raw CoQ10.
  • Best for gut support: Garden of Life Raw CoQ10.
  • Best powder form: Nootropics Depot.
  • Easiest to take: Qunol Liquid CoQ10.
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What is CoQ10 200mg used for?

Coenzyme Q10 is most commonly used for conditions that affect the heart such as heart failure and fluid build up in the body (congestive heart failure or CHF), chest pain (angina), and high blood pressure. It is also used for preventing migraine headache, Parkinson disease, and many other conditions.
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How long does it take for coenzyme Q10 to work?

Results. Plasma CoQ10 levels were significantly increased following 2 weeks of CoQ10 supplementation (p < 0.001); while a trend for higher muscle CoQ10 levels was observed after acute CoQ10 ingestion (p = 0.098).
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Can CoQ10 cause heart problems?

Researchers report that CoQ10 may have significant benefits for people with cardiovascular disease (CVD), from reducing risk for repeat heart attacks and improving outcomes in patients with heart failure to lowering blood pressure and helping combat side effects of cholesterol-lowering statins.
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What foods are high in CoQ10?

Food Sources of CoQ10
  • Organ meats: Heart, liver and kidney.
  • Some muscle meats: Pork, beef and chicken.
  • Fatty fish: Trout, herring, mackerel and sardine.
  • Vegetables: Spinach, cauliflower and broccoli.
  • Fruit: Oranges and strawberries.
  • Legumes: Soybeans, lentils and peanuts.
  • Nuts and seeds: Sesame seeds and pistachios.
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Is ubiquinol better than CoQ10?

Ubiquinol has 2x greater bioavailability and increases levels about 4x, where CoQ10 only increases 2x. This means you can take ½ the dose when you use Ubiquinol. If we want 100mg of CoQ10, you can use 50mg of Ubiquinol.
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Does CoQ10 clean arteries?

Afterwards researchers tested how well blood flowed through the arteries of people in the study. The results were encouraging. The CoQ10 supplement improved blood vessel health by about 42%, so the researchers thought this meant that the risk of heart disease was lowered by 13%.
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Does CoQ10 help with statin muscle pain?

Coenzyme Q10 supplementation ameliorated statin‐associated muscle symptoms, such as muscle pain, muscle weakness, muscle cramps, and muscle tiredness, demonstrated by the present meta‐analysis.
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