How long is it safe to take glucosamine and chondroitin?

What the Science Says About Safety and Side Effects. No serious side effects have been reported in large, well-conducted studies of people taking glucosamine, chondroitin, or both for up to 3 years.

How long should you take glucosamine chondroitin?

Most studies have shown that glucosamine needs to be taken for two to four months before its full benefits are realized, although some will experience improvement sooner. Potential side effects of glucosamine-chondroitin include: Nausea.

Is glucosamine good for long term?

Often used to treat bone and joint disorders

Multiple studies indicate that taking daily glucosamine sulfate supplements may offer effective, long-term treatment for OA by significantly reducing pain, helping maintain joint space, and slowing disease progression ( 9 , 10 , 11 , 12 ).

How long can I take chondroitin?

How much chondroitin should you take? Since chondroitin is not an established treatment, the ideal dosage is uncertain. For osteoarthritis, some studies have used 800 milligrams up to 1200 milligrams in single or divided doses for up to 3 years.

What are the risks of taking glucosamine chondroitin?

In general, glucosamine and chondroitin sulfate nutritional supplements appear to be quite safe. The most common side effects occur that have been reported are gastrointestinal in nature, such as upset stomach, nausea, heartburn, and diarrhea.

Can I stop taking glucosamine?

The Australian Rheumatology Association has issued a similar warning: stop taking glucosamine. “Glucosamine is not helpful, and can be harmful,” said Professor David Hunter, a spokesman for the association and chairman of the Institute of Bone and Joint Research at the University of Sydney.

Who should not take glucosamine chondroitin?

Glucosamine is extracted from a substance in shellfish. The effects of these supplements on a growing child or developing baby are not yet known. For that reason, glucosamine and chondroitin are not recommended for children, women who are pregnant, women who are nursing, and women who could become pregnant.

Can glucosamine cause liver damage?

Glucosamine has been implicated in isolated case reports in causing clinically apparent liver injury, but the role of glucosamine as opposed to other herbal components or contaminants has not been shown, and liver injury due to glucosamine or chondroitin must be very rare if it occurs at all.

Can you take too much chondroitin?

When taken by mouth: Chondroitin sulfate is likely safe when used for up to 6 years. It can cause some mild stomach pain and nausea. Other possible side effects include bloating, diarrhea, and constipation.

Does chondroitin rebuild cartilage?

So far studies have not shown conclusively that chondroitin helps repair or grow new cartilage, or stops cartilage from being further damaged. Chondroitin is often taken with glucosamine, another supplement that has been studied along with chondroitin for OA. Like chondroitin, glucosamine also has conflicting results.

Why you shouldn't take glucosamine?

Because glucosamine products might be derived from the shells of shellfish, there is concern that the supplement could cause an allergic reaction in people with shellfish allergies. Glucosamine might worsen asthma. There's some concern that glucosamine might raise eye pressure.

Does glucosamine hurt your kidneys?

Reintroduction of glucosamine resulted in loss of kidney function after 3 weeks, with GFR reduced from 60 to 53 mL/ min. Thus, glucosamine was shown to cause renal toxicity. Referring to other reported cases, we conclude that toxicity is rare but may also be underreported.

Does glucosamine chondroitin make you gain weight?

Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet. Metabolism. 2015 Mar;64(3):368-79. doi: 10.1016/j.

Can you take too much glucosamine and chondroitin?

Some glucosamine products also contain manganese. Taking too much of this combination can cause a manganese overdose. Do not take more than directed on the medicine label.

Does glucosamine rebuild cartilage?

Glucosamine sulphate and glucosamine hydrochloride are nutritional supplements. Animal studies have found that glucosamine can both delay the breakdown of and repair damaged cartilage. The results for the use of glucosamine for osteoarthritis are mixed and the size of the effect is modest.

What is the best vitamin for stiff joints?

Vitamin D is important for keeping bones strong and preventing injuries from falls. Research shows that people with low levels of vitamin D may have more joint pain.

How long can I take glucosamine sulfate?

When taken by mouth: Glucosamine sulfate is likely safe in most adults when used for up to 3 years. Glucosamine hydrochloride is possibly safe for most adults when used for up to 2 years.

Does chondroitin raise blood pressure?

Based on several human cases, temporary increases in blood pressure and heart rate, as well as palpitations, may occur in those taking glucosamine/chondroitin products.

What should you not take with glucosamine?

How can I get glucosamine naturally?

Glucosamine is a natural sugar that exists in the fluid around the joints, as well as in animal bones, bone marrow, shellfish, and fungi. The glucosamine in supplements usually comes from the shells of shellfish, though there is also a synthetic form.

Does glucosamine raise cholesterol?

Glucosamine is a component of the hexosamine pathway, which has been implicated in the development of insulin resistance. Anecdotal reports suggest that glucosamine consumption can increase circulating cholesterol concentrations.

Can glucosamine be toxic?

Glucosamine has been shown to be safe and well-tolerated. Common side effects are nausea, vomiting, abdominal pain, and diarrhea. There is a risk for severe and life-threatening allergic reactions to glucosamine in people with shellfish allergy or those with asthma.

What can you take to lubricate your joints?

Does glucosamine really help joints?

Glucosamine and chondroitin protect cells called chondrocytes, which help maintain cartilage structure. In theory, these supplements have the potential to slow cartilage deterioration in the joints, and to reduce pain in the process.

Is glucosamine worth taking?

A 2022 analysis of eight studies that included nearly 4,000 people with knee osteoarthritis found no convincing evidence that glucosamine and chondroitin provided major benefit. The case for these supplements protecting joint health or preventing arthritis from worsening is similarly weak.