How long does it take for HPV to become CIN1?

77.77% (91/117) of these women developed CIN1 within an estimated interval of 24 months from the recorded onset of persistent HR-HPV infection, while 22.23% (26/117) were estimated to have developed CIN1 after persistent HR-HPV infection exceeding 24 months.
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How quickly can CIN develop?

In general, it takes 10 to 20 years for CIN to progress to cancer, allowing a significant time period for detection and treatment. Progression from CIN to cancer requires persistent HPV infection.
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How long does it take for HPV to cause CIN 2?

Whereas CIN2/3 typically develops within a few years of infection with HPV (4–6), progression to invasive carcinoma is generally thought to require much more time.
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Does HPV cause CIN1?

CIN 1 is usually caused by infection with certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 1 is not cancer and usually goes away on its own without treatment, but sometimes it can become cancer and spread into nearby tissue.
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Does HPV always cause CIN?

CIN2 and CIN3 are always caused by high-risk HPV infections. The typical treatment procedure for CIN2 or CIN3 involves removing a cone-shaped piece of the cervix, called a LEEP or a cone.
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HPV



What type of HPV causes CIN1?

The results of several studies suggest that CIN1 is mainly caused by low-risk HPV infection [3–5]. However, there is also evidence that high-risk HPV is strongly associated with CIN1 [6, 7]. Differences in the risk of HPV infection and CIN1 disease outcome [8, 9] may be due to regional differences in populations.
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How often does CIN1 progress?

Overall, 82.1% of the women with CIN1 regressed within 2 years, while 1.5% progressed to a high-grade lesion within 3 years.
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Is CGIN worse than CIN?

CGIN is usually classified as low grade (mild) or high grade (severe). High grade CGIN is the equivalent of CIN3. CGIN can be multi-focal – this means that more than one area is affected at one time, with normal tissue lying between them.
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Will my CIN 1 Go Away?

With low-grade cervical dysplasia, classified as CIN 1, you likely won't need treatment. In the majority of these cases, the condition goes away on its own. Only about 1% of cases progress to cervical cancer.
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How long does it take for HPV to cause abnormal cells?

HPV-related cancers often take years to develop after getting an HPV infection. Cervical cancer usually develops over 10 or more years. There can be a long interval between being infected with HPV, the development of abnormal cells on the cervix and the development of cervical cancer.
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How effective is LEEP for CIN1?

Results: Of the 311 women who underwent LEEP, 283 reported for 1-year follow-up and 248 (87.6%) were disease free. Cure rates were 93.0% for CIN 1, 85.5% for CIN 2, and 72.7% for CIN 3. Minor adverse effects were observed in 34 women and complications were seen in 5 women.
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Can your body clear high risk HPV?

Common high-risk HPV types include HPV 16 and 18. Infection with HPV is very common. In most people, the body is able to clear the infection on its own. But sometimes, the infection doesn't go away.
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Does CIN 2 mean I have HPV?

CIN 2 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated.
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What are the stages of CIN?

Cervical intraepithelial neoplasia (CIN)
  • CIN 1 – up to one third of the thickness of the lining covering the cervix has abnormal cells.
  • CIN 2 – between one third and two thirds of the skin covering the cervix has abnormal cells.
  • CIN 3 – the full thickness of the lining covering the cervix has abnormal cells.
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Can HPV cause abnormal cells in a year?

When a high-risk HPV infection of cervical cells lasts many years, the cells can become abnormal. These changes can get worse over time and may become cervical cancer.
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What is CIN 1 on a Pap smear?

CIN 1. CIN 1 means one-third of the thickness of the cervical surface layer is affected by abnormal cells. This will often return to normal without any treatment at all. You will have further cervical smear tests or colposcopies to check the cells have improved.
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Does CIN1 affect fertility?

Treatment does not affect your fertility. If possible, check with your doctor or specialist before becoming pregnant to make sure you are up to date with your screenings. This way, you can have any necessary treatment beforehand.
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Can CGIN come back?

A doctor explains that the chances of recurrence after treatment for CIN3 / CGIN are small. If CIN3 has been completely treated, in other words the abnormality has been removed in it's entirety with a zone of normal tissue around it, then the chances of it recurring are very, very small.
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Do I need a colposcopy if I have HPV?

If you test positive for HPV 16/18, you will need to have a colposcopy. If you test positive for HPV (but did not have genotyping performed or had genotyping and tested negative for 16/18), you will likely have a colposcopy.
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What are the chances of abnormal cells returning?

After treatment for cell changes: about 9 in 10 (90%) people will not have cell changes again. fewer than 2 in 10 (between 5% and 15%) people may have cell changes that come back.
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How long does HPV high risk last?

HPV Very Rarely Becomes Cervical Cancer

For 90 percent of women with HPV, the condition will clear up on its own within two years. Only a small number of women who have one of the HPV strains that cause cervical cancer will ever actually develop the disease.
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How long does it take for HPV to turn into Lsil?

Our findings suggest that the risk of developing LSIL in young females is only present within the first 3 years after detection of HPV DNA.
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Is CIN1 benign?

1 2 Low grade squamous intraepithelial lesion (LSIL, also known as CIN1) is now recognised as a histological diagnosis of benign viral replication that should be managed conservatively, whereas CIN3 is recognised as a true pre-invasive precursor with a potential to progress to cancer.
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Can LEEP get rid of HPV?

Although LEEP does not completely eradicate HPV infection, our results indicate that most HR-HPV infections are cleared after LEEP with negative margins. The clearance rate is increasing gradually after surgery. Our persistence rate was 40.9 % at 6 months, 20 % at 12 months and 11.8 % at 18 months.
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Will removing the cervix cure HPV?

Surgically treating genital warts doesn't cure a human papillomavirus (HPV) infection, however, and warts can return after surgery if the immune system does not eliminate the infection. Surgery may be used to treat moderate to severe cervical dysplasia by removing abnormal cells on the cervix.
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