How long does clopidogrel stay in your system?

Plavix is estimated to be cleared from your body in about 33 hours. A single, oral dose of Plavix (clopidogrel) 75 mg has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for a drug to leave the body, therefore most of the Plavix should be eliminated from your system in 5.5 x 6 = 33 hours.
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How long does clopidogrel take to wear off?

How long does clopidogrel (Plavix) stay in your body? The blood-thinning effect of clopidogrel (Plavix) can last for up to 5 days after your last dose. Keep this in mind if you're going to have surgery or any kind of procedure that might cause bleeding.
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Can you stop clopidogrel suddenly?

Do not stop taking clopidogrel without first talking to your health care professional. Suddenly stopping the use of antiplatelet medicines can put you at risk for heart attacks, strokes, and blood clots. Be aware that while taking clopidogrel you may bruise more easily, and it may take longer for any bleeding to stop.
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What happens if you stop taking clopidogrel?

Do not stop taking clopidogrel without talking to your doctor. If you stop taking clopidogrel, your blood will start clotting at the same rate as before you started taking it, usually within 5 days of stopping the medicine. This means you may be at increased risk of serious problems like heart attacks or strokes.
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Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.
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How does aspirin work?



What are the most common side effects of clopidogrel?

Common side effects of clopidogrel can include:
  • headaches or dizziness.
  • nausea.
  • diarrhoea or constipation.
  • indigestion (dyspepsia)
  • stomach ache or abdominal pain.
  • nosebleeds.
  • increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.
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When is the best time to take clopidogrel 75 mg?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.
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Can clopidogrel cause anxiety?

headache, fever, weakness, feeling tired; little or no urination; a seizure; low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or.
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Does clopidogrel affect blood pressure?

You likely won't have blood pressure changes while you're taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.
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Can clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.
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What can you take instead of clopidogrel?

Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.
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Can I drink coffee with clopidogrel?

These medications are used to slow blood clotting and include aspirin, clopidogrel (Plavix), ibuprofen (Advil, Motrin, and others), naproxen (Anaprox, Naprosyn, and others), enoxaparin (Lovenox), and more. Health experts advise caution when combining them with coffee, which can also slow blood clotting.
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Which is safer aspirin or clopidogrel?

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.
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How long does it take for blood thinners to get out of your system?

This depends on the type of blood thinner, and can range from hours to days. The blood thinning effects of warfarin, aspirin, and Plavix (clopidogrel) can last for days, whereas Eliquis (apixaban) and Xarelto (rivaroxaban) wear off in about a day. Lovenox (low molecular weight heparin) wears off after about 12 hours.
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How quickly does clopidogrel work?

Some inhibition of platelet clotting is seen within two hours of taking the drug; however, it takes between three to seven days of regular clopidogrel dosing to reach its maximal effect.
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Can you stop taking blood thinners cold turkey?

One of the major risks is that blood clots may begin to form, which could lead to a stroke and a lack of oxygen to the brain. This could also potentially lead to partial paralysis or even death. Stopping a blood-thinning drug suddenly can also raise the risk for a blood clot in the brain, which is often fatal.
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Can I drink alcohol when taking clopidogrel?

Can I drink alcohol while taking clopidogrel? ️ Yes (within the recommended limits). Alcohol doesn't affect clopidogrel itself, but just be aware that drinking alcohol can irritate your stomach lining. This could increase the risk of getting a bleeding in the stomach.
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Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel.
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Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.
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Does clopidogrel affect blood sugar?

These results could indicate that clopidogrel has glucose lowering effect and the FSG level in placebo treated group significantly elevated after the same course of treatment.
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Does clopidogrel make you gain weight?

Weight changes, including weight loss, are not commonly seen with Plavix. However, Plavix has been shown to cause loss of taste in a few individuals within the first two to eight weeks of taking the medication. Patients who lose their sense of taste may also have decreased appetite, leading to weight loss.
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Can you go off Plavix cold turkey?

You should never stop taking any prescribed medication without talking to your doctor, but especially not Plavix. Patients who stop taking Plavix can develop clotting and could suffer a heart attack or stroke or other damage to their cardiovascular system.
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What should I monitor with clopidogrel?

HPR while on this drug is associated with major adverse cardiovascular events. The best assays to monitor clopidogrel therapy include VerifyNow and Multiplate ADP test.
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Does clopidogrel cause leg cramps?

It frequently occurs in the legs and often causes claudication or pain in the legs upon walking. Plavix is used to reduce the risk of heart attacks and strokes in these patients.
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How long should I take clopidogrel after a stent?

Background: American and European cardiology societies recommend six to 12 months of dual-antiplatelet therapy with aspirin and clopidogrel (Plavix) after drug-eluting stent placement to prevent late stent thrombosis.
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