How is oligodontia inherited?

Genetic Causes

If one or both of your parents experience a genetic disorder or mutation, it's not a guarantee that you will develop the same condition. Genetic causes are varied, given that oligodontia is caused by both genetic syndromes and inherited family traits.

Is oligodontia hereditary?

Oligodontia is a dental abnormality in which the patient is missing teeth. It is a hereditary disorder characterized by agenesis of more than 6 pri- mary/permanent teeth, excluding the wisdom teeth.

What causes oligodontia?

Possible causes of oligodontia include viral disease during pregnancy, genetic predisposition, metabolic imbalances, developmental abnormalities and environmental factors. Autosomal dominant mutations in PAX9 and MSX1 have been found in patients with molar non-syndromic oligodontia.

How is hypodontia passed down?

Hypodontia may be inherited in an autosomal recessive, autosomal dominant, X-linked dominant, or X-linked recessive mode. The most commonly missing permanent teeth are the third molars (20%), second premolars (3.4%), and maxillary lateral incisors (2.2%) (Simons et al. 1993).

What causes tooth agenesis?

Although dental agenesis is occasionally caused by environmental factors, such as infection (e.g. rubella), various kinds of trauma of the dental region, multi-reagent chemotherapy or radiotherapy, or disturbances in jaw innervations, in a majority of cases, hypodontia has genetic causes (1,6).

Oligodontia

Are missing teeth hereditary?

Some people are born without certain teeth, and this condition is called congenitally missing teeth. Genetic factors cause congenitally missing teeth and this condition is often seen in generations of a family. The most common missing teeth are wisdom teeth, upper lateral incisors, and second premolars/bicuspids.

Is missing permanent teeth genetic?

Congenitally missing teeth are teeth that never appear and are not trapped in the gums – they just do not exist in some people! The condition, which usually affects the lateral incisors and the second premolars, is often a harmless genetic trait passed down from parents to their children.

Is hypodontia genetic?

Hypodontia is genetic in origin and usually involves the absence of from 1 to 5 teeth. Oligodontia is genetic as well and is the term used to describe a condition in which six or more teeth are missing. Hypodontia/oligodontia/anodontia might be considered as a unique clinical entity but with increasing severity.

Which genes are associated with hypodontia?

The study of mouse genetics has uncovered a large number of candidate genes for this condition, but mutations in only three have been identified in human pedigrees with familial hypodontia or oligodontia: MSX1, PAX9 and AXIN2.

What is syndromic oligodontia?

Oligodontia is a rare genetic disorder which represents the congenital absence of more than six teeth in primary, permanent or both dentitions. It is usually a part of a syndrome and seldom occurs as an isolated entity. Genes responsible for non syndromic oligodontia are found to be MSX1 and PAX9 genes.

Is oligodontia a disability?

Conclusions: Oligodontia is a heterogeneous condition. Patients with oligodontia can be classified as having three different types according to the extent of their disability and the complexity of their prosthodontic requirements.

Are peg laterals hereditary?

Peg-shaped teeth are a hereditary dental disorder called microdontia, a condition where one or more teeth appear smaller than average (microdontia) [1]. In general, the most common teeth affected are the upper lateral incisors or sometimes third molars.

Is supernumerary teeth genetic?

Presence of supernumerary teeth is well-recognized clinical phenomenon. However, it is uncommon to find multiple supernumeraries in individuals with no other associated disease or syndrome. Presence of multiple supernumerary teeth is thought to have genetic component.

What are the commonest congenitally missing teeth?

The most common congenitally missing teeth are wisdom teeth, upper lateral incisors, and the second premolars(source).

Is having no teeth a disability?

Therefore, an individual should be considered to have a dental disability if orofacial pain, infection, or pathological condition and/or lack of functional dentition affect nutritional intake, growth and development, or participation in life activities.

How common is anodontia?

The prevalence of anodontia is unknown but it is a very rare disorder. Anodontia occurs in less than 2-8% of the general population in regards to permanent teeth and 0.1-0.7% in primary teeth.

What is the second tooth in hypodontia?

The second premolars – these are the teeth right in front of your molars. One may sometimes be removed during braces treatment, but if your child is missing this permanent tooth, chances are it's due to hypodontia.

What causes severe hypodontia?

Hypodontia is usually the result of a problem with the band of tissue under the gums (dental lamina) where the teeth form. The most common cause of these problems is heredity or family history. A mutation of one of the specific genes which help form the dental lamina properly can lead to hypodontia.

What is hypodontia vs anodontia?

Hypodontia refers to the absence of fewer than 6 teeth (not including third molars). Oligodontia refers to the absence of 6 or more teeth (not including third molars). Anodontia is the complete absence of teeth. Hypodontia is more common in the permanent dentition than in the primary dentition.

How common is missing permanent teeth?

Researchers estimate that as many as 20 percent of adults are born with at least one missing tooth, making hypodontia one of the most common developmental oral health conditions. Most individuals are missing only one or two permanent teeth, with very few missing more than six.

What do you call someone with missing teeth?

edentulous • \ee-DEN-chuh-luss\ • adjective. : having no teeth : toothless.

Can you be born with extra teeth?

Two peg-shaped teeth may form behind a child's top incisors. An entire extra mouthful of tooth buds can grow alongside a child's actual teeth. These are examples of a condition called hyperdontia. Whether the extra teeth form near deciduous or permanent teeth, they're called supernumerary teeth.

Is it rare to have an extra tooth?

Up to 3.8% of people have one or more extra (supernumerary) teeth. An extra tooth can be visible (erupted) or impacted (not broken through the gum). You may not notice hyperdontia in children.

How rare are extra wisdom teeth?

There are some extreme cases where people have even more. However, these cases are rare and you would be quite unique if you fall into this category. In fact, about one or two people in a hundred have these extra wisdom teeth. Most of the wisdom teeth I saw were twelve in one person.

Are peg lateral teeth rare?

Peg-shaped teeth are type of microdontia, a developmental disturbances of teeth mainly due to congenital reasons. Most commonly affecting single teeth, that is maxillary lateral incisors. Incidence of peg shaped tooth in maxillary laterals are usually seen and reported. But in mandibular arch it is very rare.