How effective is LEEP for CIN1?

In addition, in a study of 126 patients undergoing loop electrosurgical excisional procedure (LEEP) for persistent CIN 1 (diagnosed on two consecutive colposcopic biopsies), 87 percent had CIN 1 or NILM on the excised specimen versus 13 percent with CIN 2+ [20]. These data support a conservative approach to management.

Will HPV 16 go away after LEEP?

Although LEEP does not completely eradicate HPV infection, our results indicate that most HR-HPV infections are cleared after LEEP with negative margins. Moreover, HPV type 16 and age over 36.5 years are factors that favor infection persistence.

Can CIN come back after LEEP?

About 23% of patients develop CIN2+ after LEEP treatment due to residual or recurrent lesions. The majority of patients with HPV infection were HPV negative before treatment, but 16,4% were still HPV 16 positive after treatment, indicating that conization do not necessarily clear HPV infection rapidly.

What is the success rate of LEEP procedure?

Loop electrosurgical excision procedure (LEEP) is a common treatment for cervical intraepithelial neoplasia (CIN), with success rates of 60 to 95 percent reported.

Is LEEP recommended for CIN1?

The clinical management of women with CIN 1 lesions may take one of the following courses: (i) immediate treatment or (ii) follow the woman and then treat if the lesion is persistent or progressive after 18 to 24 months. All women with CIN 2 and CIN 3 lesions should be treated with cryotherapy or LEEP.

What is CIN

What is the best treatment for CIN 1?

The two main management approaches to CIN are observation (with human papillomavirus [HPV] testing, cervical cytology, and/or colposcopy) or treatment with excision or ablation of the cervical transformation zone; the choice between treatment options is discussed in detail elsewhere.

How do you make CIN 1 Go Away?

There is no cure or treatment for it. BUT your body can clear it and have it go dormant, and cell changes can be treated. CIN1 is the least serious form of cell abnormality and it may well clear on its own with no intervention, just monitoring more regularly.

Do abnormal cells come back after LEEP?

LEEP works very well to treat abnormal cell changes on the cervix. If all of the abnormal tissue is removed, you won't need more surgery. In some studies, doctors were able to remove all the abnormal cells in almost every case. But abnormal cells may come back in the future.

What will LEEP results show?

The purpose of a LEEP is to extract abnormal cells for further testing. The results will inform a doctor about whether a person has an underlying illness and what steps they should take next. A LEEP can help distinguish between precancerous cells and other abnormal cell types, such as polyps.

What is the next step after LEEP procedure?

The most common next step after a LEEP procedure is to get a pap smear in six months. It is Really Important to get a follow-up pap smear, after the LEEP procedure.

How long does it take to clear HPV 16?

Progression depends on the type of HPV strain and on the unique characteristics of the individual who is infected. The longer the virus is present, the higher the potential for a cancer to develop. The good news is that more than 90% of HPV 16 and 18 infections go away within 6 to18 months of initial exposure.

How do I get rid of persistent HPV 16?

How common is a second LEEP procedure?

3.2% (7 patients) were diagnosed with HSIL and underwent a second LEEP. This study found that 14.0% of patients (n = 31) required further follow up based on findings at the second colposcopy follow up visit.

How long does cin1 take to develop?

Fifth, the estimated infection duration from onset to CIN development ranged between 4 and 70 months, with 73.65% of women being diagnosed with CIN within 24 months from baseline. A number of advances have been made in CC screening over the years.

Can you be reinfected with HPV 16?

The results also show that men who are infected once with HPV16, the type responsible for most HPV-related cancers, are at 20 times higher risk of reinfection after one year, and 14 times higher after two years.

How many times can LEEP be performed?

If the margins are positive, you may need a repeat procedure. In addition, six months following a LEEP, you'll have a follow-up appointment that includes Pap and HPV tests. In some cases, abnormal cells are found again. If this happens, you may require another LEEP.

Can you have CIN 1 without HPV?

HPV infection is necessary but not sufficient to develop CIN. More than 90% of infections are spontaneously cleared by the immune system within one year without treatment.

What happens if the LEEP procedure doesn't work?

If LEEP doesn't remove all of the abnormal cells, you may have to have LEEP again, or your doctor or nurse may recommend more tests or a different treatment.

How does the cervix heal after LEEP?

Don't place anything inside your vagina (such as tampons or douches) or have vaginal intercourse for at least 4 weeks after your procedure. It usually takes about this long for your cervix to heal. During your follow-up appointment, your doctor will examine you and see if your cervix has healed.

Can CIN return after treatment?

Definitely. A few women we spoke interviewed did have a recurrence of abnormal cells after treatment for CIN3, and this was often found at a follow-up appointment. Most were treated again by LLETZ.

Why does HPV keep coming back?

There's no guarantee that genital warts won't grow back again because HPV changes the cells of your body in a way that makes them likely to grow. If you have high-risk HPV that sticks around or goes dormant and keeps coming back, that's when it becomes cancer causing (or what doctors call oncogenic).

How effective is the LEEP procedure for CIN 3?

Factors influencing cure rates were evaluated by chi(2) tests. Results: Of the 311 women who underwent LEEP, 283 reported for 1-year follow-up and 248 (87.6%) were disease free. Cure rates were 93.0% for CIN 1, 85.5% for CIN 2, and 72.7% for CIN 3.

Did your CIN 1 Go Away?

CIN 1 cervical dysplasia rarely becomes cancer and often goes away on its own.

How serious is CIN1?

CIN 1 is not cancer and usually goes away on its own without treatment, but sometimes it can become cancer and spread into nearby tissue. CIN 1 is sometimes called low-grade or mild dysplasia. Also called cervical squamous intraepithelial neoplasia 1.

Is CGIN worse than CIN?

CGIN is usually classified as low grade (mild) or high grade (severe). High grade CGIN is the equivalent of CIN3. CGIN can be multi-focal – this means that more than one area is affected at one time, with normal tissue lying between them.