How does Vitamin D3 interact with statins?

Interactions between your drugs
No interactions were found between simvastatin and Vitamin D3. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Can you take Vitamin D3 with a statin?

Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
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What medications should not be taken with Vitamin D3?

Possible interactions include:
  • Aluminum. ...
  • Anticonvulsants. ...
  • Atorvastatin (Lipitor). ...
  • Calcipotriene (Dovonex, Sorilux). ...
  • Cholestyramine (Prevalite). ...
  • Cytochrome P-450 3A4 (CYP3A4) substrates. ...
  • Digoxin (Lanoxin). ...
  • Diltiazem (Cardizem, Tiazac, others).
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What supplements should not be taken with statins?

A magnesium- and aluminum-containing antacid was reported to interfere with atorvastatin absorption. People can avoid this interaction by taking atorvastatin two hours before or after any aluminum/magnesium-containing antacids. Some magnesium supplements such as magnesium hydroxide are also antacids.
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Can you take vitamin D and cholesterol together?

In fact, the researchers found that the supplements were actually associated with an increase in LDL. However, 2014 research found that taking calcium and vitamin D supplements together improved cholesterol levels in postmenopausal, overweight, or obese women.
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Does Vitamin D3 raise cholesterol?

Higher vitamin D levels appear to be associated with higher total cholesterol levels and higher HDL cholesterol levels, according to a new study presented at the American College of Cardiology's (ACC) 65th Annual Scientific Sessions.
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Do statins deplete vitamin D?

Cholesterol is converted into 7-dehydrocholesterol, which is then converted to the active form of vitamin D in the presence of sunlight. Taking the above into consideration, since statins reduce cholesterol levels, they could interfere with the formation of vitamin D and therefore cause vitamin D deficiency.
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Can I take vitamin D and Lipitor?

No interactions were found between calcium / vitamin d and Lipitor. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Is it OK to take multivitamins with statins?

No interactions were found between Daily Multi-Vitamins with Minerals and simvastatin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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Why do statins make your legs ache?

The researchers suggest that in most people, muscle cells can tolerate this calcium leak. However, in people already susceptible due to their genes or lifestyle, the leak caused by statins may overwhelm the muscle cells, giving rise to muscle pain and weakness.
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What medications does vitamin D3 interfere with?

Most frequently checked interactions
  • amlodipine.
  • aspirin.
  • Aspirin Low Strength (aspirin)
  • atorvastatin.
  • CoQ10 (ubiquinone)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • folic acid.
  • gabapentin.
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Can vitamin D3 cause heart problems?

The dose of the vitamin D supplements given also varied greatly, as did the length of the studies. Barbarawi said the researchers were surprised to see that vitamin D supplements didn't appear to have any effect on major heart problems, stroke or death.
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Does vitamin D3 interfere with other medications?

Critical vitamin D3-drug interactions

Several commonly prescribed medications have a negative impact on vitamin D status. Medications most likely to affect the status or actions of vitamin D3 include those used to manage hyperlipidemia, arthritis, diabetes, depression, asthma, and COPD5.
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How does vitamin D affect atorvastatin?

The conclusion of the study is that vitamin D supplementation lowers atorvastatin and active metabolite concentrations yet has synergistic effects on cholesterol concentrations.
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How much Vitamin D3 should I take daily?

The current recommendations suggest consuming 400–800 IU (10–20 mcg) of vitamin D per day. However, people who need more vitamin D can safely consume 1,000–4,000 IU (25–100 mcg) daily. Consuming more than this is not advised, as it is not linked to any extra health benefits.
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Does vitamin D interfere with blood pressure medication?

After comparing both individual patient data and the overall findings for each study, researchers found that vitamin D supplements had no significant effect on blood pressure. In other words, patients taking vitamin D supplements had similar changes in blood pressure as those taking an inactive placebo drug.
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Can I drink coffee while taking statin?

Caffeine is a nonspecific adenosine receptor blocker, and thus drinking CC may block the myocardial protective effects of statins.
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Should CoQ10 be taken at the same time with statins?

Some researchers have suggested that low levels of coenzyme Q10 can lead to the muscle aches that can be associated with statin use. With that in mind, coenzyme Q10 supplements have sometimes been recommended for people who take statins.
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What should you not take with atorvastatin?

While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.
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Can you take D3 with Lipitor?

Interactions between your drugs

No interactions were found between Lipitor and Vitamin D3.
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What vitamins can be taken with atorvastatin?

No interactions were found between atorvastatin and Vitamins. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
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What vitamin deficiency is caused by statins?

Introduction. Statin-associated muscle symptoms are common side effects of statin therapy. These symptoms include myopathy, myalgia, and rhabdomyolysis. Vitamin D has been associated with musculoskeletal health; thus, its deficiency may produce detrimental effects in this tissue.
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Does vitamin D clog arteries?

People with diabetes often develop clogged arteries that cause heart disease, and new research at Washington University School of Medicine in St. Louis suggests that low vitamin D levels are to blame. In a study published Nov.
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What can I take instead of statins to lower cholesterol?

7 cholesterol-lowering alternatives to statins
  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis. ...
  • Plant stanols and sterols. ...
  • Cholestyramine and other bile acid-binding resins. ...
  • Niacin. ...
  • Policosanol. ...
  • Red yeast rice extract (RYRE) ...
  • Natural products.
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What is the best vitamin to take to lower cholesterol?

Niacin. This B vitamin can boost HDL “good" cholesterol and lower LDL “bad” cholesterol and triglycerides -- but only use it if your doctor advises you to. Only prescription-level doses impact cholesterol and triglycerides.
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