How does melanoma start inside the body?

Melanoma is a type of skin cancer that develops when melanocytes (the cells that give the skin its tan or brown color) start to grow out of control. Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer, and can then spread to other areas of the body.
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How does internal melanoma start?

It's likely that a combination of factors, including environmental and genetic factors, causes melanoma. Still, doctors believe exposure to ultraviolet (UV) radiation from the sun and from tanning lamps and beds is the leading cause of melanoma.
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How do you know if melanoma has spread internally?

Symptoms of metastatic melanoma other than a mole

Lungs – A persistent cough or shortness of breath. Brain – Headaches or seizures. Lymph nodes – Swelling of the lymph nodes. Liver – Loss of appetite or unexplained weight loss.
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How does melanoma enter the body?

Melanoma begins when healthy melanocytes change and grow out of control, forming a cancerous tumor. A cancerous tumor is malignant, meaning it can grow and spread to other parts of the body. Sometimes, melanoma develops from a normal mole that a person already has on their skin.
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What does melanoma look like inside the body?

Color that is uneven: Shades of black, brown, and tan may be present. Areas of white, gray, red, pink, or blue may also be seen. Diameter: There is a change in size, usually an increase. Melanomas can be tiny, but most are larger than the size of a pea (larger than 6 millimeters or about 1/4 inch).
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What are the stages of melanoma?



Can melanoma occur internally?

Although melanoma usually grows on the skin, it can also grow in mucosal membranes. This moist tissue lines cavities inside the body, such as the mouth, nose, sinuses and pelvic organs. About half of mucosal melanomas start in the head and neck, such as: Nose or sinuses.
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Can melanoma spread inside your body?

Melanoma cells can spread from the primary tumor through the bloodstream and lymphatic system to form new tumors. Melanoma, the most aggressive form of skin cancer, is often incurable once the cancer has spread from the original site of the tumor to distant organs and tissues.
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What are the warning signs of melanoma?

Spread of pigment from the border of a spot into surrounding skin. Redness or a new swelling beyond the border of the mole. Change in sensation, such as itchiness, tenderness, or pain. Change in the surface of a mole – scaliness, oozing, bleeding, or the appearance of a lump or bump.
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What organs are affected by melanoma?

Melanoma can spread to almost anywhere in the body but the most common places for it to spread are the:
  • lymph nodes.
  • lungs.
  • liver.
  • bones.
  • brain.
  • tummy (abdomen)
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What are symptoms of stage 1 melanoma?

Symptoms of stage 1 skin cancers can look like changes in skin lesions or moles, or the development of new moles that are characterized by asymmetry, irregular edges, having multiple colors, and size greater than ¼ inch.
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Can internal melanoma be cured?

Stage IV melanoma is difficult to cure as it has already spread to other parts of the body. However, a growing number of people respond well to treatment, achieve No Evidence of Disease (NED), and survive for many years.
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Is internal melanoma curable?

Melanoma is the most invasive skin cancer with the highest risk of death. While it's a serious skin cancer, it's highly curable if caught early. Prevention and early treatment are critical, especially if you have fair skin, blonde or red hair and blue eyes.
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How fast does melanoma spread to organs?

How fast does melanoma spread and grow to local lymph nodes and other organs? “Melanoma can grow extremely quickly and can become life-threatening in as little as six weeks,” noted Dr. Duncanson.
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How long can you have melanoma before knowing?

How long can you have melanoma and not know it? It depends on the type of melanoma. For example, nodular melanoma grows rapidly over a matter of weeks, while a radial melanoma can slowly spread over the span of a decade. Like a cavity, a melanoma may grow for years before producing any significant symptoms.
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What feeds melanoma?

The major cause of skin cancer is ultraviolet (UV) rays from the sun or from tanning machines. About 90 percent of nonmelanoma skin cancers and 86 percent of melanomas are associated with solar UV, and more than 419,000 cases of skin cancer in the U.S. each year are linked to indoor tanning.
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How is internal melanoma treated?

Metastases that cause symptoms but cannot be removed may be treated with radiation, immunotherapy, targeted therapy, or chemotherapy. The treatment of widespread melanomas has changed in recent years as newer forms of immunotherapy and targeted drugs have been shown to be more effective than chemotherapy.
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Who is at greatest risk for melanoma?

People with fair complexion, blond or red hair, blue eyes, and freckles are at increased risk for developing melanoma. This risk is also higher for people whose skin has a tendency to burn rather than tan. Family history. About 10% of people with melanoma have a family history of the disease.
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Who is mostly affected by melanoma?

The risk of melanoma increases as people age. The average age of people when it is diagnosed is 65. But melanoma is not uncommon even among those younger than 30. In fact, it's one of the most common cancers in young adults (especially young women).
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When is melanoma too late?

What are the signs of late-stage skin cancer? Melanoma is considered stage 4 when it has metastasized to lymph nodes in a part of the body far from the original tumor or if it has metastasized to internal organs like the lungs, liver, brain, bone or gastrointestinal tract.
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Do blood tests detect melanoma?

Blood tests aren't used to diagnose melanoma, but some tests may be done before or during treatment, especially for more advanced melanomas. Doctors often test blood for levels of a substance called lactate dehydrogenase (LDH) before treatment.
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What does pre melanoma look like?

Discoloration, often appearing brown, pink, gray, red, yellow, or white. Flat or slightly raised. Hard or wart-like surface. Roughness or scaly skin.
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At what age does melanoma usually occur?

[1-4] In contrast to most cancer types, melanoma skin cancer also occurs relatively frequently at younger ages. Age-specific incidence rates increase steadily from around age 20-24 and more steeply in males from around age 55-59. The highest rates are in in the 85 to 89 age group for females and males.
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How long can you live with melanoma untreated?

In the very early stages the 5-year survival rate is 99%. Once melanoma has spread to the lymph nodes the 5-year survival rate is 63%. If melanoma spreads to other parts of the body, the 5-year survival drops to just 20%.
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Where does melanoma start?

Melanomas can develop anywhere on the skin, but they are more likely to start on the trunk (chest and back) in men and on the legs in women. The neck and face are other common sites.
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How do you stop melanoma from spreading?

The most common treatment for most superficial spreading melanoma is to have it removed surgically. This may or may not include having surgery to remove affected lymph nodes as well. Even for melanoma that has spread to distant parts of the body, surgery may be able to remove cancer from those sites.
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